A review of Vicieae lectins studies: End of the book or a story in the writing?

Purification and characterization of a highly thermostable GlcNAc-binding lectin from Collaea speciosa seeds

“…After addition of Ca 2+ or Mn 2+ ions, a partial restoration of the activity was observed, while full activity was recovered only after the addition of both divalent cations. These results show that CsL, similar to most Diocleinae lectins, is dependent on metal ions, such as Ca 2+ and Mn 2+ (Figure 3CD and Table 3) [7,51]. Judging from the absence of PAS staining CsL, does not have any covalently attached glycan in its structure in contrast to the positive control lectin (VML) (Figure 4) [52,53].…”

“…For instance, some plant lectins bind to porphyrins and phthalocyanines, which are photosensitizers used in clinical imaging for cancer cell detection with particular application in photodynamic therapy (PDT) [5,6]. Studies with lectins from the Diocleinae subtribe reported that they possess a hydrophobic site capable of interacting with hydrophobic molecules, such as 2-ptoluidinonaphthalene-6-sulfonate, hydrophobic sugar derivatives, phytohormones and auxin (e.g., indole-3-acetic acid or IAA, a naturally occurring auxin) [7].…”

Recent advances in the use of legume lectins for the diagnosis and treatment of breast cancer

“…Other BCa cell lines have been used to test the cytotoxicity of lectins (Table 1). Some review papers demonstrate the diversity of plant lectins with their potential biological activities and the purification processes and structural characterization [155][156][157][158][159].…”