A Review of: “Users' Guides to the Medical Literature: A Manual for Evidence-Based Clinical Practice. 2nd Ed. Guyatt, Gordon; Rennie Drummond; Meade, Maureen; and Cook, Deborah eds.”

Hasman, L

doi:10.1080/02763860902817238

Cited by 7 publications

(10 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The absolute risk is defined as the probability that an event will occur [1,2,6]. We commonly refer to the risk of the adverse outcome in the control group as the baseline risk.…”

Section: Measure Of Absolute Effect Absolute Riskmentioning

confidence: 99%

“…The risk difference (RD), also known as the absolute risk reduction (ARR) [1,2], allows trialists to describe the difference in outcome rates using absolute terms (i.e., absolute risk in control group (timolol)absolute risk in treatment group (laser)). Accordingly, the RD in our working example is 0.69-0.39 = 0.3.…”

Section: Risk Differencementioning

confidence: 99%

“…Randomized clinical trials are the gold standard for informing the effectiveness of therapeutic interventions, and often report a variety of effect measures that readers should consider [1]. Commonly used measures for dichotomous outcomes in randomized controlled trials include absolute risk, risk difference, relative risk, relative risk reduction, and odds ratio [1,2]. These measures can be broadly categorized as conveying either absolute or relative effects and, depending on the choice of measure(s) used by authors, treatment effects may appear larger or smaller despite being based on the same data [1,2].…”

Section: Introductionmentioning

confidence: 99%

“…Commonly used measures for dichotomous outcomes in randomized controlled trials include absolute risk, risk difference, relative risk, relative risk reduction, and odds ratio [1,2]. These measures can be broadly categorized as conveying either absolute or relative effects and, depending on the choice of measure(s) used by authors, treatment effects may appear larger or smaller despite being based on the same data [1,2]. This may lead clinicians to make different treatment decisions depending on how the results are presented [2][3][4].…”

Section: Introductionmentioning

confidence: 99%

“…These measures can be broadly categorized as conveying either absolute or relative effects and, depending on the choice of measure(s) used by authors, treatment effects may appear larger or smaller despite being based on the same data [1,2]. This may lead clinicians to make different treatment decisions depending on how the results are presented [2][3][4]. Thus, it is imperative that clinicians understand how to interpret trial data, independently of the narrative of the sponsoring group, and be able to convey this information to patients to optimize shared decision-making.…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Interpreting results from randomized controlled trials: What measures to focus on in clinical practice

Darzi

Busse

Phillips

et al. 2023

Eye

View full text Add to dashboard Cite

“…The absolute risk is defined as the probability that an event will occur [1,2,6]. We commonly refer to the risk of the adverse outcome in the control group as the baseline risk.…”

Section: Measure Of Absolute Effect Absolute Riskmentioning

confidence: 99%

Section: Risk Differencementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Interpreting results from randomized controlled trials: What measures to focus on in clinical practice

Darzi

Busse

Phillips

et al. 2023

Eye

View full text Add to dashboard Cite

How to Interpret and Use a Clinical Practice Guideline or Recommendation

Brignardello‐Petersen

Carrasco-Labra

Guyatt

2021

JAMA

View full text Add to dashboard Cite

IMPORTANCEClinicians may rely on recommendations from clinical practice guidelines for management of patients.OBSERVATIONS A clinical practice guideline is a published statement that includes recommendations that are intended to optimize patient care. In the guideline development process, a panel of experts formulates recommendation questions that guide the retrieval of evidence that is used to inform the recommendations. Typically, methods of guideline development, a summary of the supporting evidence, and a justification of the panel's decisions accompany the recommendations. To use such guidelines optimally, clinicians must understand the implications of the recommendations, assess the trustworthiness of the development process, and evaluate the extent to which the recommendations are applicable to patients in their practice settings. Helpful recommendations are clear and actionable, and explicitly specify whether they are strong or weak, are appropriate for all patients, or depend on individual patients' circumstances and values. Rigorous guidelines and recommendations are informed by appropriately conducted, up-to-date systematic reviews that consider outcomes important to patients. Because judgments are involved in the interpretation of the evidence and the process of moving from evidence to recommendations, useful guidelines consider all relevant factors that have a bearing in a clinical decision and are not influenced by conflicts of interest. CONCLUSIONS AND RELEVANCEIn considering a guideline's recommendations, clinicians must decide whether there are important differences between the factors the guideline panel has considered in making recommendations and their own practice setting.

show abstract

Bilimde Kanıta Ulaşmak

YUVANÇ

AKALTAN

2022

Selcuk Dental Journal

View full text Add to dashboard Cite

Diş hekimliğinde uygulanacak tedaviler ve bunlar hakkındaki bilgiler çoğu zaman klinik deneyimlerden yola çıkarak öğrenilip aktarılmaktadır. Günümüz diş hekimliğinde kanıta dayalı bilginin değeri gün geçtikçe artarken kanıta ulaşmada izlenmesi gereken yollar henüz yeteri kadar bilinmemektedir. Kaynağa ulaşmak için ilk olarak öğrenilmek istenen bilgiyi doğru bir şekilde soruya çevirip araştırmak gerekmektedir. Literatürde bulunan kaynakların bilime katkıları ve kanıt düzeyleri farklıdır. Sorunun yönlendirdiği kaynakların kanıt düzeyleri bilginin nasıl elde edildiği ve hangi klinik vakalara uyarlanabilir olduklarına göre değişmektedir. Araştırmanın klinik ortamda gerçekleştirilmesi ve randomizasyonun doğru yapılması kanıt düzeyini yüksek kılmaktadır. Kaynaklar değerlendirilirken kanıt düzeyi sıralamaları göz önünde bulundurularak istenilen bilgiye ulaşılmalıdır. Kanıt değeri en yüksek olan Randomize Kontrollü Çalışmalar literatürler arasında doğru bilgiye en yakın kanıtı sunan kaynaklardır. Literatür taramalarında öncelikli olarak bu kaynakların araştırılması kanıta dayalı diş hekimliğinin yaygınlaşması için bir gerekliliktir.

show abstract

A Review of: “Users' Guides to the Medical Literature: A Manual for Evidence-Based Clinical Practice. 2nd Ed. Guyatt, Gordon; Rennie Drummond; Meade, Maureen; and Cook, Deborah eds.”

Cited by 7 publications

References 0 publications

Interpreting results from randomized controlled trials: What measures to focus on in clinical practice

Interpreting results from randomized controlled trials: What measures to focus on in clinical practice

How to Interpret and Use a Clinical Practice Guideline or Recommendation

Bilimde Kanıta Ulaşmak

Contact Info

Product

Resources

About