A review of ultrasound-assisted extraction for plant bioactive compounds: Phenolics, flavonoids, thymols, saponins and proteins

Yusoff, Ida Madiha; Taher, Zarani Mat; Rahmat, Zaidah; Chua, Lee Suan

doi:10.1016/j.foodres.2022.111268

Cited by 169 publications

(103 citation statements)

References 147 publications

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“…Phenolic compounds are considered to represent one of the most important pharmaceutical and nutraceutical markers for the further uses of plant extracts [ 11 ]. With this in mind, we determined the total concentrations of phenolics and flavonoids using colorimetric methods.…”

Section: Resultsmentioning

confidence: 99%

“Smart Extraction Chain” with Green Solvents: Extraction of Bioactive Compounds from Picea abies Bark Waste for Pharmaceutical, Nutraceutical and Cosmetic Uses

et al. 2022

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Secondary metabolites from the sawmill waste Picea abies bark were extracted using an innovative two-step extraction that includes a first step with supercritical CO2 (SCO2) and a second step using green solvents, namely ethanol, water, and water ethanol mixture. Maceration (M), ultrasound assisted extraction (UAE) and microwave assisted extraction (MAE) techniques were applied in the second step. A total of nineteen extract were obtained and yield were compared. Bark extracts were characterized by LC-DAD-MSn and classes of compounds were quantified as abietane derivatives, piceasides, flavonoids, and phenolics to compare different extractions. Obtained extracts were studied by in vitro assay to evaluate potential pharmaceutical, nutraceutical and cosmetic uses assessing the antioxidant activity as well as the inhibitory activity on target enzymes. Results show that the “smart extraction chain” is advantageous in term of yield of extraction and phytoconstituent concentration. SCO2 extract, presenting a unique composition with a large amount of abietane derivatives, exerted the best activity for amylase inhibition compared to the other extracts.

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Section: Resultsmentioning

confidence: 99%

“Smart Extraction Chain” with Green Solvents: Extraction of Bioactive Compounds from Picea abies Bark Waste for Pharmaceutical, Nutraceutical and Cosmetic Uses

et al. 2022

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“…A reduction of almost ~28% of the phenolic acids and ~49.4% of flavonoids was found in such seeds after US treatment, which indicates that this technology, applied at the described conditions, did not report an improvement in the biosynthesis of phenolic compounds, and it should be further investigated to test its benefits. As a matter of fact, the extraction parameters such as temperature, time, frequency, power, and type of solvent are essential factors to control in the extraction of bioactive compounds by applying US [ 19 ], and the origin or the cultivar also affect the phytochemical profile. In this sense, although US technology helps to recover bioactive compounds from a different food matrix, it is necessary to also control parameters such as color, pH, or particle size of suspension, which also influence the breaking of the chemical bond of bioactive compounds.…”

Section: Resultsmentioning

confidence: 99%

Ultrasounds and a Postharvest Photoperiod to Enhance the Synthesis of Sulforaphane and Antioxidants in Rocket Sprouts

2022

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Ultrasounds (US) and LED illumination are being studied to optimize yield and quality. Evaluate the effect of a pre-sowing US treatment combined with a postharvest photoperiod including LEDs on rocket sprouts’ quality and phytochemicals during shelf life. A US treatment (35 kHz; 30 min) applied to seeds and a postharvest photoperiod of 14 h fluorescent light (FL) + 10 h White (W), Blue (B), Red (R) LEDs or Darkness (D) were assayed. Antioxidants as phenolics and sulfur compounds (glucosinolates and isothiocyanates) were periodically monitored over 14 days at 5 °C. The US treatment increased the sulforaphane content by ~4-fold compared to CTRL seeds and sprouts. The phenolic acids and the flavonoid biosynthesis were enhanced by ~25%, ~30%, and ~55% under photoperiods with W, B, and R, respectively, compared to darkness. The total glucosinolate content was increased by >25% (W) and >45% (B and R) compared to darkness, which also reported increases of ~2.7-fold (W), ~3.6-fold (B), and ~8-fold (R) of the sulforaphane content as a main isothiocyanate. Postharvest lighting is an interesting tool to stimulate the secondary metabolism, while a US treatment was able to increase the sulforaphane content in seeds and sprouts, although no synergistic effect was reported.

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“…Although ethanolic solvents, with different percentages of ethanol, were mostly used (>50% of the studies included in Table 1 ), other authors selected solvents such as acetone, water, and methanol. It is essential to clarify that polar solvents (mainly water) extract more hydrophilic compounds (which only participate in reaction with oxygen–hydrogen bonds as sugars), and ethanolic solvents (which participate in reaction with oxygen–hydrogen and polar carbon–oxygen as ethanol) are more effective in extracting phenolic compounds [ 24 ]. The solvent changes depending on the target bioactive compounds; for instance vegetal oil was used as a solvent to extract carotenoids.…”

Section: Pomegranate Peel Phenolic Compounds Extraction Techniquesmentioning

confidence: 99%

From Pomegranate Byproducts Waste to Worth: A Review of Extraction Techniques and Potential Applications for Their Revalorization

Cano‐Lamadrid

Martínez-Zamora

Castillejo

et al. 2022

Foods

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The food industry is quite interested in the use of (techno)-functional bioactive compounds from byproducts to develop ‘clean label’ foods in a circular economy. The aim of this review is to evaluate the state of the knowledge and scientific evidence on the use of green extraction technologies (ultrasound-, microwave-, and enzymatic-assisted) of bioactive compounds from pomegranate peel byproducts, and their potential application via the supplementation/fortification of vegetal matrixes to improve their quality, functional properties, and safety. Most studies are mainly focused on ultrasound extraction, which has been widely developed compared to microwave or enzymatic extractions, which should be studied in depth, including their combinations. After extraction, pomegranate peel byproducts (in the form of powders, liquid extracts, and/or encapsulated, among others) have been incorporated into several food matrixes, as a good tool to preserve ‘clean label’ foods without altering their composition and improving their functional properties. Future studies must clearly evaluate the energy efficiency/consumption, the cost, and the environmental impact leading to the sustainable extraction of the key bio-compounds. Moreover, predictive models are needed to optimize the phytochemical extraction and to help in decision-making along the supply chain.

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A review of ultrasound-assisted extraction for plant bioactive compounds: Phenolics, flavonoids, thymols, saponins and proteins

Cited by 169 publications

References 147 publications

“Smart Extraction Chain” with Green Solvents: Extraction of Bioactive Compounds from Picea abies Bark Waste for Pharmaceutical, Nutraceutical and Cosmetic Uses

“Smart Extraction Chain” with Green Solvents: Extraction of Bioactive Compounds from Picea abies Bark Waste for Pharmaceutical, Nutraceutical and Cosmetic Uses

Ultrasounds and a Postharvest Photoperiod to Enhance the Synthesis of Sulforaphane and Antioxidants in Rocket Sprouts

From Pomegranate Byproducts Waste to Worth: A Review of Extraction Techniques and Potential Applications for Their Revalorization

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