A review of the utilization of fine needle aspiration in clinical practice and research in Nigeria

Malami, Sani; Ochicha, Ochicha

doi:10.4103/1742-6413.82277

Cited by 10 publications

(18 citation statements)

References 20 publications

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“…This is also consistent with most findings [9-11]. Generalized lymphadenopathy in all reports and in this study was due to lymphomas [5,8-11,14]. …”

Section: Discussionsupporting

confidence: 94%

“…Cervical group of lymph nodes showed a higher incidence of tuberculosis in children followed by axillary group (Table 3) consistent with findings of other workers [10,11]. …”

Section: Discussionsupporting

confidence: 91%

“…However, while no case of metastatic leukemic infiltrate was recorded in our centre during the period of study, other workers reported leukemic infiltrate [9-11]. This could be attributed to the fact that in our centre, leukemic patients are diagnosed by hematologists using bone marrow aspirate, and are thus usually referred to them for management even with lymphadenopathy.…”

Section: Discussionmentioning

confidence: 66%

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Role of Fine Needle Aspiration Cytology (FNAC) as a Diagnostic Tool in Paediatric Head and Neck Lymphodenopathy

et al. 2014

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A neck mass that is present for longer than a week might be pathological requiring rapid and thorough evaluation. This study aims to evaluate the positive role Fine needle aspiration cytology plays in the diagnosis of pediatric patients with lymphadenopathy in the head and neck region. Fine needle aspiration of lymph nodes was carried out, fixed and stained by cytopathologists for 56 patients at the Jos University Teaching Hospital, 43 (76.8%) were inflammatory and 13 (23.2%) malignant. Reactive hyperplasia (72.1%), acute suppurative (18.6%) and tuberculosis (9.3%) constituted the inflammatory lesions. Non Hodgkins lymphoma was the commonest malignant lesion (76.9%) followed by Hodgkins lymphoma (15.4%), the least being Rhabdomyosarcoma (7.7%). Age range 10-14 years had the highest number of cases (46.4%). Males were 36 (64.3%) while females were 20 (35.7%). All malignant cases diagnosed by FNAC had to undergo confirmation/characterization by histology and had 100% concordance. Thus there were no false positives and specificity was 100%, sensitivity 100%. Of the 43 diagnosed as inflammatory by FNAC, 12 cases which did not resolve after treatment or where patients condition worsened had to undergo surgical biopsy. Out of these only 1 (8.3%) case of fungal infection was misdiagnosed by FNAC. The lymph nodes were generalized 4 (7.1%) and localized in 52 (92.9%). Maximum number of cases 53 (94.6%) had Cervical Lymphadenopathy followed by axillary 2 (3.6%) and inguinal 1 (1.8%). Out of the cervical group of nodes, the upper anterior and upper posterior deep cervical nodes were involved in majority of cases (95%).

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“…This is also consistent with most findings [9-11]. Generalized lymphadenopathy in all reports and in this study was due to lymphomas [5,8-11,14]. …”

Section: Discussionsupporting

confidence: 94%

“…Cervical group of lymph nodes showed a higher incidence of tuberculosis in children followed by axillary group (Table 3) consistent with findings of other workers [10,11]. …”

Section: Discussionsupporting

confidence: 91%

Section: Discussionmentioning

confidence: 66%

See 1 more Smart Citation

Role of Fine Needle Aspiration Cytology (FNAC) as a Diagnostic Tool in Paediatric Head and Neck Lymphodenopathy

et al. 2014

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“…These values are comparable to those documented in similar studies (10)(11)(12)(13)(14) and much higher than >60% for specificity and > 80% for sensitivity recommended by NHSBSP of Britain (7). The high values for sensitivity, specificity and overall diagnostic accuracy obtained in this study may be due to the fact that only palpable lumps were sampled and the fact that most of the patients presented late with large lumps.…”

Section: Discussionsupporting

confidence: 77%

Sub-classification of Breast Masses by Fine Needle Aspiration Cytology

Madubogwu

Ukah

Anyanwu

et al. 2017

Eur J Breast Health

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IntroductionBreast lump is one of the commonest presentations of breast diseases. The diagnosis of breast diseases can be achieved like in other clinical conditions using: history, physical examination and investigation which include cytological or histological confirmation. Currently, several studies have advocated the use of 'Triple test' which consists of clinical examination, radiologic examination and cytopathology as more accurate means of making diagnosis of breast lesions (1-5). When all the three components are positive, diagnostic accuracy approaches 100% for malignancy (2). Fine Needle Aspiration cytology (FNAC) is widely used and accepted as a reliable method of making initial pre-operative diagnosis in breast diseases (2, 6). It has been credited with a lot of advantages such as: high accuracy, cheap, fast, out-patient procedure reducing pressure on theatre load, high patient acceptability, and low complication rate (2, 6).Fine Needle Aspiration cytology reports are classified into 5 categories based on the National Health Services Breast Screening Programme (NHSB-SP) of Britain (7). The use of these standardized diagnostic categories is necessary to enhance communication within a multi-disciplinary team and for comparing results from other Centres. The diagnostic categories and their corresponding numerical codes are: Inadequate/insufficient (C1); Benign (C2); Atypical/indeterminate (C3); Suspicious of malignancy (C4) and Malignant (C5). However, Specimen from FNAC can be used to sub-classify breast lesions (7-9). Most studies on FNAC do not make attempt at sub-classifying breast lesions into definite disease types because of the challenges usually encountered (8, 9). The aim of this study is to evaluate the accuracy of sub-classification of breast diseases using FNAC in our Centre. Eur J Breast Health 2017; 13: 194-9 DOI: 10.5152/ejbh.2017.3506 194 ABSTRACT Objective: The aim of this study is to evaluate the accuracy of sub-classification of breast diseases using Fine Needle Aspiration cytology (FNAC). Materials and methods:A one-year prospective study of 180 consecutive patients with palpable breast lesions who underwent FNAC and subsequently open surgical biopsy for histological confirmation. FNAC was used to sub-classify breast lesions and then correlated with histological diagnosis.Results: A total of 180 patients were enrolled into the study but only 110 patients with histology report were used for test validity. Seventeen (15.5%) smears were C1; while 46 (41.8%), 5 (4.5%), 4 (3.6%) and 38 (34.6%) were C2, C3, C4 and C5, respectively. FNAC achieved sensitivity of 90.0%, specificity of 95.5%, false positive rate of 5.3%, false negative rate of 8.7%, positive predictive value of 94.7%, negative predictive value of 91.3% and overall diagnostic accuracy of 92.9%. Only 86 (78.2%) of the 110 smears could be sub-classified into different disease conditions of the breast on cytology. FNAC accurately sub-classified 25(78.1%) of fibroadenoma and 28(87.5%) of invasive ductal carcinoma. Conclusion:F...

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“…The 2012 IF for CytoJournal was calculated based on citations from 2010[11121314151617181920212223242526272829303132333435363738] to 2011[3940414243444546474849505152535455565758596061] CytoJournal publications within the articles from indexed journals published in 2012. [1] Considering the trend over 5 years (2008-2012), CytoJournal's IF of 1.2 for 2012 is comparable with the other peer reviewed cytopathology journals [Table 1 and Figure 2].…”

mentioning

confidence: 99%

Announcement of first time Cytojournal impact factor for 2012 coincides with Cytojournal decade celebration (2004-2013)

Shidham

DeMay

2013

CytoJournal

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A review of the utilization of fine needle aspiration in clinical practice and research in Nigeria

Cited by 10 publications

References 20 publications

Role of Fine Needle Aspiration Cytology (FNAC) as a Diagnostic Tool in Paediatric Head and Neck Lymphodenopathy

Role of Fine Needle Aspiration Cytology (FNAC) as a Diagnostic Tool in Paediatric Head and Neck Lymphodenopathy

Sub-classification of Breast Masses by Fine Needle Aspiration Cytology

Announcement of first time Cytojournal impact factor for 2012 coincides with Cytojournal decade celebration (2004-2013)

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