A Review of the Synthesis and Biological Activity of Flavonoid Mannich Base Derivatives
Van‐Son Nguyen,
Vo Thanh Cong,
Tran Nguyen Minh An
Abstract:Over the past twenty years (1998–2023), extensive research has focused on the synthesis and biological activity of Mannich base derivatives of flavonoids (FMBD), which have demonstrated exceptional properties towards organic and bioorganic molecules. Several research groups have reported the pharmacological potential of these flavonoid derivatives, including antioxidant and antiviral activities, as well as their ability to inhibit AChE and exhibit anticancer properties. Moreover, the unique characteristic of f… Show more
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