Definition of interplanetary dust particle hypervelocity impact protection levels provided by spacecraft multilayer insulation/thermal blankets is provided for the first time. Development of a new data-anchored shock-hydrocodecomputations-derived ballistic limit equation in the 7-150 km∕s hypervelocity impact range for representative twowall Whipple shields, in which spacecraft multilayer insulation is the bumper material impacted by fused silica dust, is presented. A baseline configuration was adopted for analysis: 0.0176-cm-thick Kapton bumper (monolithic and layered), 2.54 cm standoff, and 0.0762-cm-thick titanium alloy Ti-6Al-4V rear wall. Significant efforts made to verify and validate the computational methodology with hypervelocity impact test data are also described. With a solid Kapton bumper, the critical particle diameter for causing incipient spall in the rear wall, which is chosen to be the failure criterion, is found to be in the ∼650-1100 μm range, with the largest and the smallest sizes corresponding to 30 and 150 km∕s hypervelocity impact, respectively. When the bumper is layered in a manner similar to that found in actual blankets (140 μm spacing), the critical particle diameter is indicated to be in the ∼450-600 μm range.