A review of the phytochemistry and medicinal activities of the popular African food additive: Parkia biglobosa seed

Balogun, Wasiu Gbolahan; Adebayo, Ismail Abiola; Yusuf, Usman; Seeni, Azman

doi:10.1007/s13596-018-0337-7

Cited by 7 publications

(5 citation statements)

References 34 publications

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“…The delayed healing of these lesions is mainly due to the impaired immunity and increased risk of infections associated with secondary LE, thereby the increased chronicity and difficulty in the management of filarial wounds. The crushed seeds of P. biglobosa has proven to have wound‐healing abilities toward snakebit among the Fulani tribes of northern Nigeria 45 . In LF there are several reports of sustained bacterial infection as cause of chronic wounds in LF pathologies, and this could be mitigated through treatment with P. biglobosa which has been shown to have wound healing activity 46 .…”

Section: Prospects Of Medicinal Plants Against Chronic Wounds Among F...mentioning

confidence: 99%

“…The crushed seeds of P. biglobosa has proven to have wound‐healing abilities toward snakebit among the Fulani tribes of northern Nigeria. 45 In LF there are several reports of sustained bacterial infection as cause of chronic wounds in LF pathologies, and this could be mitigated through treatment with P. biglobosa which has been shown to have wound healing activity. 46 Study has also shown that aqueous extracts of neem leaves have wound‐healing ability and this is an appropriate option, preferred for its naturality, ease of access, and is safe, with no known adverse effect.…”

Section: Prospects Of Medicinal Plants Against Chronic Wounds Among F...mentioning

confidence: 99%

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Use of medicinal plants as a remedy against lymphatic filariasis: Current status and future prospect

Fordjour,

Osei‐Poku,

Genfi

et al. 2023

Health Science Reports

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Despite the successes achieved so far with the Global Programme to Eliminate Lymphatic Filariasis, there is still an appreciable number of lymphatic filarial patients who need alternative treatment and morbidity management strategies.The unresponsiveness of some cohorts to the drugs used in the mass drug administration program is currently raising a lot of questions and this needs urgent attention. Natural medicinal plants have a long-standing history of being effective against most disease conditions. Countries such as India have been able to integrate their natural plant remedies into the treatment of lymphatic filarial conditions, and the results are overwhelmingly positive. Components of Azadirachta indica A. Juss, Parkia biglobosa, Adansonia digitata, and Ocimum spp have been shown to have anti-inflammatory, anticancerous, and antimicrobial activities in animal models. Therefore, this review calls for attention toward the use of natural plant components as an alternate treatment against lymphatic filariasis to help reduce the World Health Organization's burden of providing drugs for people in need of treatment every year.

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Section: Prospects Of Medicinal Plants Against Chronic Wounds Among F...mentioning

confidence: 99%

Section: Prospects Of Medicinal Plants Against Chronic Wounds Among F...mentioning

confidence: 99%

Use of medicinal plants as a remedy against lymphatic filariasis: Current status and future prospect

Fordjour,

Osei‐Poku,

Genfi

et al. 2023

Health Science Reports

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“…Phytochemical screening shows that it contains polyterpenes, polyphenols flavonoids, catechictannins, saponin, and sterols (Kassi et al, 2018). Oil from of Parkia biglobosa seed have been reported to contain arachidic, stearic, palmitic, behenic, and linoleic acids (Balogun et al, 2018).…”

Section: Parkia Biglobosamentioning

confidence: 99%

A review of some common African spices with antihypertensive potential

Adeoye

Joel

Igunnu

et al. 2021

Journal of Food Biochemistry

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Hypertension is the most common non-communicable disease, with about 1.28 billion hypertensive people worldwide. It is more prevalent in men than women and more common in the elderly. Hereditary, age, obesity, lifestyle, diet, alcohol, and chronic metabolic diseases are the major risk factors of hypertension. Treating hypertension is a complex process as there are several mechanisms responsible for its pathogenesis; hence, a combination of several drugs is used for managing hypertension. Drugs used in managing hypertension are expensive and often come with associated side effects; thus, there is need for alternative means of managing this life-threatening disease. These drugs do not achieve the recommended blood pressure target in most people; more so majority of people with hypertension do not follow the treatment regimen religiously. Some Africans have been reported to become normotensive as a result of dietary consumption of spices. Several spices have been used over the years in Africa to manage hypertension. The aim of this review is to evaluate the ethnomedicinal use, bioactive phytochemical composition, bioactive compounds present, and pharmacological applications of spices commonly used in Africa for managing hypertension. Most of the plants used contained polyphenols, flavonoids, tannins, anthraquinone, flavonoids, cardiac glycosides, and saponins. Dietary supplementation of Xylopia aethiopica and other spices in diet have been proven to significantly reduced plasma angiotensin-I-converting enzyme (ACE) than simvastatin (the reference drug). Toxicological, histological, and hematological evaluation revealed that acute and chronic consumption of most of these spices are safe. Studies have also revealed that some of the spices can be used as alternative therapy alongside usual antihypertensive medications. Practical implication:The prevalent rate of hypertension is on the increase in both the developed and developing countries. People often skip medication due to their busy schedule and anti-hypertensive potential side effects; however, this is not the case with food/spices as most people consumed them daily. Deliberate, right combinations and consistent incorporation of spices with proven anti-hypertensive potential into our diet may be of great benefit in normalizing blood pressure and mitigate other complications on the heart and vital organs.Hypertension or elevated blood pressure means the persistent force of blood against the artery wall leading to increase in blood pressure. According to World Health Organisation (WHO, 2021), blood pressure on two different days with both days exceeding 140/90 mmHg is classified as hypertension. The first (higher) number is the systolic, which is the blood pressure when the heart contracts, while the second (lower number) is the diastolic, which is the blood pressure when the heart relaxes (Ondimu et al., 2019). It is usually measured using upper arm cuff; however wrist devices are used for obese persons with extreme size of the arm (Nerenberg et al., 2018). Accordi...

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“…Benth or Parkiaclappertoniana (Keay) is a perennial tropical plant legume of the family Fabaceaefound ingallery forests in Benin republic, Burkina Faso, Cote d'Ivoire, Cameroun, Nigeria, and Mali. It is a tree that can go up to 30 m in height, with red globular, red globose inflorescence; pod variable, flat, and seed-bearing [1] [2]. The fruit is a slightly bent, brown indehiscent pod, 30 to 40 cm long and 2 to 3 cm wide producing up to 20 seeds [3].…”

Section: Introductionmentioning

confidence: 99%

“…The fruit is a slightly bent, brown indehiscent pod, 30 to 40 cm long and 2 to 3 cm wide producing up to 20 seeds [3]. The different parts (leaves, bark, and roots) of this plant are known for several of their biological properties: anti-inflammatory, antibacterial, diarrhea, antidiabetic, abdominal pains, Gastric and duodenal ulcer, antihypertensive activity, and hepatic deficiency [2] [3]. The seeds were known for: food condiments obtained by fermentation, such as afitin and sonru in the republic of Benin [4]; iru and dawadawa in Nigeria [5]; soumbala in Burkina Faso [6], and for their oil termiticidal properties [7].…”

Section: Introductionmentioning

confidence: 99%

<i>Parkia biglobosa</i> Fruit Husks: Phytochemistry, Antibacterial, and Free Radical Scavenging Activities

Bothon¹,

Atindehou²,

Koudoro³

et al. 2023

AJPS

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Known for their role in the manufacture of eco-materials in buildings, Parkia biglobosa fruit husks are also used in folk medicine. The present study focuses on the metabolites content and antiradical, antibacterial activities of the hydroethanolic extract of P. biglobosa husks. Secondary metabolites were identified using staining and/or precipitation tests. The mineral content is determined according to the standard NF EN 14082. The antioxidant activity performed by 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging capacity, and antibacterial activity strain against three Gram-negative and two Grampositive strains by microdilution for Minimal Inhibitory Concentration. Fruit husks contain tannins, anthocyanins, leuco-anthocyanins, anthraquinones, saponins, reducing compounds, sterols, terpenes, and 1.225% of potassium.The hydroethanolic extract of P. biglobosa fruit husks scavenges the DPPH radical with an EC50 = 64 µg/ml. The extract is more active in one Gram (Pseudomonas aeruginosa and Escherichia coli) with a minimum inhibitory concentration of 1.25 mg/mL than the three Gram + studied. This study showed that P. biglobosa fruit husks extract could be used for its antioxidant and antibacterial activities.

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A review of the phytochemistry and medicinal activities of the popular African food additive: Parkia biglobosa seed

Cited by 7 publications

References 34 publications

Use of medicinal plants as a remedy against lymphatic filariasis: Current status and future prospect

Use of medicinal plants as a remedy against lymphatic filariasis: Current status and future prospect

A review of some common African spices with antihypertensive potential

<i>Parkia biglobosa</i> Fruit Husks: Phytochemistry, Antibacterial, and Free Radical Scavenging Activities

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A review of the phytochemistry and medicinal activities of the popular African food additive: Parkia biglobosa seed

Cited by 7 publications

References 34 publications

Use of medicinal plants as a remedy against lymphatic filariasis: Current status and future prospect

Use of medicinal plants as a remedy against lymphatic filariasis: Current status and future prospect

A review of some common African spices with antihypertensive potential

&lt;i&gt;Parkia biglobosa&lt;/i&gt; Fruit Husks: Phytochemistry, Antibacterial, and Free Radical Scavenging Activities

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<i>Parkia biglobosa</i> Fruit Husks: Phytochemistry, Antibacterial, and Free Radical Scavenging Activities