A review of the flortaucipir literature for positron emission tomography imaging of tau neurofibrillary tangles
Samantha C Burnham,
Leonardo Iaccarino,
Michael J Pontecorvo
et al.
Abstract:Alzheimer’s disease is defined by the presence of β-amyloid plaques and neurofibrillary tau tangles potentially preceding clinical symptoms by many years. Previously only detectable postmortem, these pathological hallmarks are now identifiable using biomarkers, permitting an in vivo definitive diagnosis of Alzheimer’s disease. 18F-flortaucipir (previously known as 18F-T807; 18F-AV-1451) was the first tau positron emission tomography tracer to be introduced and is the only Food and Drug Administration approved … Show more
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