A Review of the Effects of Adolescent Cannabis Use on Physical Health

Tuvel, Abigail L.; Winiger, Evan A.; Ross, J. Megan

doi:10.1016/j.chc.2022.07.005

Cited by 2 publications

(3 citation statements)

References 181 publications

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“…Chronic cannabis use has been linked to an increased risk for developing airway diseases and lung cancer [130,131]. Several studies have demonstrated gastrointestinal symptoms (nausea, vomiting, and thirst) after using cannabis [124,132]. Decreased fertility, miscarriages, reduced sperm function, lowering of thyroid hormones, and increased risk of diabetes and fractures can all be caused by the effects of cannabis and cannabinoids on the endocrine system [133].…”

Section: Approved Drugs Of Natural Originmentioning

confidence: 99%

“…Biochemical and structural changes in the brain Some severe neurological symptoms [112][113][114] [ [115][116][117] Reproductive system Decreased fertility, miscarriages, reduced sperm function [133] Cardiovascular system Tachycardia and arterial hypertension [127] Respiratory system Decreased airway resistance [128][129][130][131] Gastrointestinal system Nausea, vomiting, thirst [124,132] Endocrine system…”

Section: Central Nervous Systemmentioning

confidence: 99%

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Cannabis as a Source of Approved Drugs: A New Look at an Old Problem

Gabarin,

Yarmolinsky,

Budovsky

et al. 2023

Molecules

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Cannabis plants have been used in medicine since ancient times. They are well known for their anti-diabetic, anti-inflammatory, neuroprotective, anti-cancer, anti-oxidative, anti-microbial, anti-viral, and anti-fungal activities. A growing body of evidence indicates that targeting the endocannabinoid system and various other receptors with cannabinoid compounds holds great promise for addressing multiple medical conditions. There are two distinct avenues in the development of cannabinoid-based drugs. The first involves creating treatments directly based on the components of the cannabis plant. The second involves a singular molecule strategy, in which specific phytocannabinoids or newly discovered cannabinoids with therapeutic promise are pinpointed and synthesized for future pharmaceutical development and validation. Although the therapeutic potential of cannabis is enormous, few cannabis-related approved drugs exist, and this avenue warrants further investigation. With this in mind, we review here the medicinal properties of cannabis, its phytochemicals, approved drugs of natural and synthetic origin, pitfalls on the way to the widespread clinical use of cannabis, and additional applications of cannabis-related products.

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Section: Approved Drugs Of Natural Originmentioning

confidence: 99%

Section: Central Nervous Systemmentioning

confidence: 99%

Cannabis as a Source of Approved Drugs: A New Look at an Old Problem

Gabarin,

Yarmolinsky,

Budovsky

et al. 2023

Molecules

View full text Add to dashboard Cite

show abstract

“…According to a national report, 24% of young adults aged 18 to 25 years consumed cannabis in the past month, which is the highest prevalence compared to other age groups ( SAMHSA, 2022 ). Of concern, cannabis use is associated with a range of adverse consequences including cannabis-related motor vehicle accidents ( Hammond et al, 2020 ), mental illness ( Hosseini & Oremus, 2019 ), physical health and sleep problems ( Tuvel et al, 2023 ), and cannabis use disorder ( Connor et al, 2021 ). However, a significant portion of the variance in cannabis use negative consequences is unexplained by cannabis consumption alone ( Pearson, 2019 ), which underscores the need for a broader array of risk factors to comprehensively understand the etiology of such consequences among cannabis users.…”

mentioning

confidence: 99%

The Interaction of Cannabis Consumption with Heavy Episodic Drinking and Alcohol-Induced Blackouts in Relation to Cannabis Use Consequences Among Recent Undergraduate College Cannabis Users

Guo,

Dai,

Ward

et al. 2023

Cannabis

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Introduction: Risky alcohol use patterns, characterized by heavy episodic drinking (HED) and alcohol- induced blackout, are prevalent in college students. However, it is not clear if experiencing HED and blackout among college-attending cannabis users heightens risk for adverse cannabis use consequences. The purpose of this study was to examine whether heavy episodic drinking and blackout episodes moderate the relationship between cannabis consumption and cannabis use consequences among college students. Methods: Undergraduate college students (n = 4331) were recruited from a Midwest University in 2021. This analysis used a subset of data from past 6-month cannabis users (n= 772; 17.8% of the full sample). Among cannabis users, 64.5% identified as female and 87.8% were White with an average age of 19.99 (SD=2.88). A linear regression was conducted with two two-way interactions of cannabis consumption and HED frequency as well as cannabis consumption and alcohol-induced blackout episodes. Results: Results showed a statistically significant positive association between cannabis consumption and cannabis use consequences (B=0.73, p<.001), adjusting for the other variables in the model. Blackout, but not HED, was a significant moderator (B=0.19, p=.003). Discussion: The findings of this study indicate that blackout experiences amplify the relationship between cannabis use and cannabis-related consequences among college students. This underscores that blackouts not only signal a risk of problematic drinking but also exacerbate the association between cannabis use and its negative consequences. Conclusion: Findings may inform college campus interventions targeting cannabis and alcohol concurrent-users who experience alcohol-induced blackouts to reduce their additional risk for cannabis-related consequences.

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A Review of the Effects of Adolescent Cannabis Use on Physical Health

Cited by 2 publications

References 181 publications

Cannabis as a Source of Approved Drugs: A New Look at an Old Problem

Cannabis as a Source of Approved Drugs: A New Look at an Old Problem

The Interaction of Cannabis Consumption with Heavy Episodic Drinking and Alcohol-Induced Blackouts in Relation to Cannabis Use Consequences Among Recent Undergraduate College Cannabis Users

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