A review of the effect of medicinal plant on helminthic infections

Abstract

Nowadays, parasitic worm infection is one of the most critical global health problems. Worm infections cause severe detriments to the livestock industry and also it can cause irreparable damages to immunocompromised persons. Therefore, the present study aimed to review conducted research on the treatment of worm diseases using medicinal plants’ extract. In this systematic review, seven databases including 4 English (Scopus, PubMed, ScienceDirect, Google Scholar) and 3 Persian databases (Magiran, ISC, SID) were obtained between 2008 and 2020 to evaluate conducted studies related to the aim of the current review. Most of the studies focused on the Balanites aegyptiaca and Carica papaya plant. Water was the most common solvent (38.1%) and then it was methanol. The most studied parasite was Haemonchus contortus (35.5%), followed by Aacharidia galli (10.5%). Studies showed that plant extracts could reduce effect of worm infections in the host compared to synthetic drugs. Plant extracts can produce a medicine based on natural compounds and effective on worms with fewer side effects than synthetic drugs.

Phytochemical and in vitro anthelmintic properties of mesocarp of fruit extracts from Balanites aegyptiaca (L.) Delile (Zygophyllaceae)

“…The leaves of Saba senegalensis also has vermicidal effects (97.77% of dead worms), similar to that of the pulp of B. aegyptiaca (43). The bioactive compounds present in the mesocarp of the fruit of B. aegyptiaca and secondary plant metabolites, such as saponins, triterpenes, and flavonoids, could interact on the motility of worms (44,45). Saponins can inhibit parasite development.…”

Acute Toxicity and Anthelmintic Effects of <i>Gomphrena </i><i>serrata</i> L. (Amaranthaceae) Extracts on Adult Worms and Eggs of <i>Haemonchus </i><i>c</i><i>ontortus</i>

“…Medicinal plants are a group of great socio-economic importance because they contain active components for treating various diseases [13]. This is why the middle and poor strata of Africa and the world often resort to certain plants with therapeutic virtues to treat or alleviate certain diseases [14] [15] [16].…”

Evaluation of Therapeutic Efficacy of Nanoparticles Against Secondary Cystic Hydatidiosis

“…Additionally, we looked into how well FLBZ-stacked mPEG-PCL nanoparticles worked to treat E. granulosus protoscoleces and sores (Farhadi et al 2018). Later, the use of recently organized compounds, achieved by ligand-attaching NPs to modified surfaces, as well as electromagnetically created nanodrugs, could be useful for creating modified information as an alternative to the majority of currently available medications against these ignored parasitic hydatid disease (Khamesipour et al 2021).…”