A Review of Pediatric Chronic Kidney Disease

Kaspar, Cristin; Bholah, Reshma; Bunchman, Timothy E.

doi:10.1159/000441737

Cited by 106 publications

(105 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…But the crucial difference between adult and paediatric ESRD lies in the aetiology of CKD. Adult CKD is predominately diabetic nephropathy and HTN whereas the top cause of paediatric CKD is congenital anomalies of the kidney and urinary tract (CAKUT), hereditary nephropathies and glomerulonephritis [31,32]. In the present research, age category was highly associated with blood pressure (p <0.0001).…”

Section: Discussionmentioning

confidence: 50%

Prevalence Patterns of Chronic Kidney Disease among School Children and Adolescents in a School in Varanasi, India

Kumar¹

2019

OAJUN

View full text Add to dashboard Cite

Background: Chronic kidney disease is relatively uncommon in children but can be a devastating illness with several long-term consequences. There is no consensus on the utility of screening programs of chronic kidney disease for children. Community based studies on prevalence of chronic kidney disease in children is very few. The present study aims to estimate the prevalence of chronic kidney disease in apparently healthy school children and adolescents in a screening program in a local school of Varanasi. Methods: The study subjects constituted 118 healthy school children and adolescents, screened as a part of World Kidney Day celebration. Information on age, sex, height, weight, smoking and alcohol, history of diabetes mellitus and hypertension, familial history of kidney disease was extensively interrogated and clinical investigations like, urinalysis and serum creatinine levels were recorded. Chronic kidney disease outcome was detected based on estimated glomerular filtration rate levels and albuminuria. The association of each variable with the outcome was seen using Pearson's Chi square test. Results: The overall prevalence of chronic kidney disease was 9.3%. The median age of the study participants were 10 years. There was nearly equal proportion of children in both the sexes. Hypertension and albuminuria were associated with chronic kidney disease. Conclusion: Children with chronic kidney disease comprise a very small but important portion of the total chronic kidney disease population. A regular screening process is required to study the prevalence of paediatric chronic kidney disease before one reaches to a stage of irreversible adverse outcome.

show abstract

Section: Discussionmentioning

confidence: 50%

Prevalence Patterns of Chronic Kidney Disease among School Children and Adolescents in a School in Varanasi, India

Kumar¹

2019

OAJUN

View full text Add to dashboard Cite

show abstract

“…Хвороби органів сечовидільної системи (СВС) у дітей залишаються актуальною меди-ко-соціальною проблемою як в Україні, так і в різних країнах світу, про що свідчить високий рівень захворюваності та смертності [1][2][3][4], труднощі в діагностиці [5] у зв'язку з тим, що приблизно у 50 % дітей вони проходять малосимптомно або взагалі не мають клініч-них проявів на неонатальному етапі. Значна частина нефроурологічної патології у дітей раннього та старшого віку формується ще у пренатальному періоді, коли відбувається закладка основ будови й функціонування органів СВС [6].…”

Section: вступunclassified

Immunohistochemical Characteristics of Some Mesenchymal and Epithelial Markers Expression in the Kidneys, Ureters and Bladder of Wag Rats Descendants That Developed Under Physiological Conditions

Sorokina¹,

Myroshnychenko²,

Kapustnyk³

et al. 2018

Fiziol Zh

View full text Add to dashboard Cite

Визначено особливості експресії мезенхімальних (віментину, гладеньком'язового актину, десміну) та епітеліальних (цитокератинів 18 та 19) WAG; плід; новонароджений; нирка; сечовід; сечовий міхур; віментин; гладеньком'язовий актин; десмін; цитокератини 18 та 19.

show abstract

“…The prevalence of paediatric end stage renal disease has increased over the past three decades (Kaspar et al . ). To date, use of stable isotopic methodology in children with chronic kidney disease (CKD) has been challenging due to issues related to the use and type of dialysis, which may necessitate methodological changes to the calcium protocols commonly employed among children.…”

Section: Introductionmentioning

confidence: 97%

Using stable isotope tracers to study bone metabolism in children

O’Brien

Abrams

2018

The Journal of Physiology

View full text Add to dashboard Cite

Skeletal mineralization is initiated in utero and continues throughout childhood and adolescence. During these key periods of the life cycle, calcium retention must increase significantly to provide sufficient mineral for bone deposition and skeletal growth. Stable calcium isotopes have served as a fundamental tool to non-invasively characterize the dynamic changes in calcium physiology that occur from infancy through adolescence. These approaches have helped define the dynamics of calcium absorption and utilization in healthy children and in children with chronic diseases. As data in this area have accumulated, new areas of emphasis are beginning to characterize the determinants of variability in mineral retention, the genetic determinants of bone turnover and calcium flux and the impact of the gut microbiome on whole body and niche specific calcium dynamics. Advances in these areas will help define calcium utilization in paediatric populations and provide information that may be useful in maximizing bone acquisition across this critical phase of the life cycle.

show abstract

A Review of Pediatric Chronic Kidney Disease

Cited by 106 publications

References 46 publications

Prevalence Patterns of Chronic Kidney Disease among School Children and Adolescents in a School in Varanasi, India

Prevalence Patterns of Chronic Kidney Disease among School Children and Adolescents in a School in Varanasi, India

Immunohistochemical Characteristics of Some Mesenchymal and Epithelial Markers Expression in the Kidneys, Ureters and Bladder of Wag Rats Descendants That Developed Under Physiological Conditions

Using stable isotope tracers to study bone metabolism in children

Contact Info

Product

Resources

About