A review of patient perspectives on generics substitution: what are the challenges for optimal drug use

Payers endorse generics to enhance prescribing efficiency: impact and future implications, a case history approach

“…However, there are concerns with the effectiveness and tolerability of generics compared with originator drugs [3,7,24,[31][32][33][34][35][36][37], with some originator companies questioning the quality of generics as part of their marketing strategies to reduce the erosion of sales which follow patent loss [38]. Whilst these concerns typically only apply to a minority of situations [34,36,39], as demonstrated for instance by 'dispense as written' prescriptions only accounting for 2.7% of prescriptions written by physicians in the US [30], failure by health authorities, physicians and pharmacists to adequately address these concerns will mean reduced savings in reality [3-5, 17, 40].…”

Antiepileptic Drug Nonadherence and Its Predictors among People with Epilepsy

“…Even though around 70% of people who had epilepsy supposed to be seizure-free with optimum AED treatment, many people with epilepsy did not take their antiepileptic drugs appropriately and the mortality rate in nonadherent patients was more than threefold higher than that of adherent one [17–19]. The consequence of AEDs nonadherence behavior has been associated with poor seizure control, increased morbidity and mortality along with increased time of hospitalization, worsened patient outcome, poor quality of life, and increased health care cost [20–23].…”

Impacto de intervenções para promoção do uso de medicamentos genéricos: revisão sistemática

“…A frequent problem is the polysemy of the term "generic drug" due to its different definitions according to each national legislation 11 . However, most users seem to accept replacement with generic drugs 12 . In recent years, trust and use of generics has increased, especially in developed countries, due to educational efforts, increased monitoring of good manufacturing practices, ensuring quality of medication and the greater communication of users with their caregivers 13,14 .…”