A Review of Medication Use as an Indicator of Human Health Impact in Environmentally Stressed Areas

Hollingworth, Samantha; Kim, Diane Dabok; Jagals, Paul

doi:10.1016/j.aogh.2016.01.010

Cited by 5 publications

(6 citation statements)

References 38 publications

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“…In consequence, the significant increase in the use of measured OTC medication according to the thermal environment could be a useful tool for the surveillance of gastrointestinal and respiratory diseases to identify and anticipate outbreaks. () In this context, it should be mentioned that OTC medicines play an increasing role in managing symptoms associated with mild to moderate respiratory diseases due to the growing self‐care movement …”

Section: Discussionmentioning

confidence: 99%

“…The consumption of medication, especially over‐the‐counter (OTC) drugs, may reflect a lesser degree of severity in morbidity. However, relatively few studies have used this response variable as the main variable, and most of those which have done so() used daily medical prescriptions or refundable drugs supplied to patients affiliated to the social security system/medical insurance, thereby limiting the results to severe or chronic cases within the framework of drug consumption.…”

Section: Introductionmentioning

confidence: 99%

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Short‐term effects of heat and cold on respiratory drug use. A time‐series epidemiological study in A Coruña, Spain

Royé

Figueiras

Taracido

2018

Pharmacoepidemiology and Drug

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The consumption of medication, especially over-the-counter drugs, can reflect environmental exposure with a lesser degree of severity in terms of morbidity. The non-linear effects of maximum and minimum apparent temperature on respiratory drug sales in A Coruña from 2006 to 2010 were examined using a distributed lag nonlinear model. In particular, low apparent temperatures proved to be associated with increased sales of respiratory drugs. The strongest consistent risk estimates were found for minimum apparent temperatures in respiratory drug sales with an increase of 33.4% (95% CI, 12.5%-58.0%) when the temperature changed from 2.8°C to -1.4 °C. These findings may serve to guide the planning of public health interventions to predict and manage the health effects of exposure to the thermal environment for lower degrees of morbidity. More precisely, significant increases in the use of measured over-the-counter medication could be used to identify and anticipate influenza outbreaks due to a more sensitive degree of the data source.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Short‐term effects of heat and cold on respiratory drug use. A time‐series epidemiological study in A Coruña, Spain

Royé

Figueiras

Taracido

2018

Pharmacoepidemiology and Drug

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“…Point source pollutants are still able to affect air quality even in cities that may not be heavily industrialized (Oiamo et al, 2015). Geographic location is a key contributor to ambient exposure to pollutants likely increasing the prevalence of hypertension Hollingworth et al, 2016;Poulter et al, 2015).…”

Section: Multiple Exposuresmentioning

confidence: 99%

“…Neighbourhoods of lower socioeconomic status are also associated with poorer noise and air quality and higher exposure levels to environmental stressors . Traffic-related noise and particulate matter have also been associated with increased blood pressure Hollingworth et al, 2016). Morello-Frosch et al (2007) suggest that an area that has lower socioeconomic status is the result of poor planning because they are typically situated around urban areas that are heavily polluted because of industrialized patterns.…”

Section: Rationale and Objectivesmentioning

confidence: 99%

A multiple regression analysis of cardiovascular health risks of exposure to environmental stressors in Toronto, Canada

Sadakhom¹

2021

Preprint

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This thesis examines the effects of exposure to ambient noise and air pollution and access to available greenspace on cardiovascular health in Toronto, Ontario. The study is focused around the population health approach which is used to understand the health of the whole population and to reduce health inequalities amongst population groups. The study utilizes population data from the 2012-2014 Canadian Community Health Survey (CCHS), air quality data from 2010-2014, noise exposure data from 2016, and the DMTI land use parks and recreation data to conduct a logistic regression analysis. The results from the analysis showed significant effects for noise when evaluated individually and measured cumulatively with air pollution and greenspace. Greenspace showed significant results when controlling for behavioural covariates, whereas air pollution displayed conflicting results for acute exposure. Future research on multiple environmental stressors should look to validate the importance of both ambient stressors through a longitudinal study.

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“…Medication use has been shown to be a more objective and reliable measure of health outcomes than health measures based on self-reported symptoms alone [14,15]. A review of the literature has indicated that when medication use is available, it should be considered a feasible (and perhaps preferable) indicator of environmental health [16]. A small number of studies have focused on the relationship between aircraft noise levels and medication use by airport residents, suggesting an association with the use of antihypertensive medication, and possibly psychotropic drugs or sleep medication [17][18][19][20].…”

Section: Introductionmentioning

confidence: 99%

The role of aircraft noise annoyance and noise sensitivity in the association between aircraft noise levels and medication use: results of a pooled-analysis from seven European countries

et al. 2021

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Background Few studies have considered aircraft noise annoyance and noise sensitivity in analyses of the health effects of aircraft noise, especially in relation to medication use. This study aims to investigate the moderating and mediating role of these two factors in the relationship between aircraft noise levels and medication use among 5860 residents of ten European airports included in the HYENA and DEBATS studies. Methods Information on aircraft noise annoyance, noise sensitivity, medication use, and demographic, socio-economic and lifestyle factors was collected during a face-to-face interview at home. Medication was coded according to the Anatomical Therapeutic Chemical (ATC) classification. Outdoor aircraft noise exposure was estimated by linking the participant’s home address to noise contours using Geographical Information Systems (GIS) methods. Logistic regressions with adjustment for potential confounding factors were used. In addition, Baron and Kenny’s recommendations were followed to investigate the moderating and mediating effects of aircraft noise annoyance and noise sensitivity. Results A significant association was found between aircraft noise levels at night and antihypertensive medication only in the UK (OR = 1.43, 95%CI 1.19–1.73 for a 10 dB(A)-increase in Lnight). No association was found with other medications. Aircraft noise annoyance was significantly associated with the use of antihypertensive medication (OR = 1.33, 95%CI 1.14–1.56), anxiolytics (OR = 1.48, 95%CI 1.08–2.05), hypnotics and sedatives (OR = 1.60, 95%CI 1.07–2.39), and antasthmatics (OR = 1.44, 95%CI 1.07–1.96), with no difference between countries. Noise sensitivity was significantly associated with almost all medications, with the exception of the use of antasthmatics, showing an increase in ORs with the level of noise sensitivity, with differences in ORs among countries only for the use of antihypertensive medication. The results also suggested a mediating role of aircraft noise annoyance and a modifying role of both aircraft noise annoyance and noise sensitivity in the association between aircraft noise levels and medication use. Conclusions The present study is consistent with the results of the small number of studies available to date suggesting that both aircraft noise annoyance and noise sensitivity should be taken into account in analyses of the health effects of exposure to aircraft noise.

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A Review of Medication Use as an Indicator of Human Health Impact in Environmentally Stressed Areas

Cited by 5 publications

References 38 publications

Short‐term effects of heat and cold on respiratory drug use. A time‐series epidemiological study in A Coruña, Spain

Short‐term effects of heat and cold on respiratory drug use. A time‐series epidemiological study in A Coruña, Spain

A multiple regression analysis of cardiovascular health risks of exposure to environmental stressors in Toronto, Canada

The role of aircraft noise annoyance and noise sensitivity in the association between aircraft noise levels and medication use: results of a pooled-analysis from seven European countries

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