In order to explore the research of cross-media art design, a cross-media art design research based on artificial intelligence digital service platform was put forward. Firstly, this paper analyzes the relationship between cross-media art design and artificial intelligence, and tries to find the balance point between them.Secondly, based on the information technology of cross-media art, this paper analyzes the development mode and development trend of cross-media digital culture.Finally, with the help of case analysis, it is shown that with the help of artificial intelligence digital service, artistic creative thinking can generate very specific works of art, such as painting works generated by deep learning algorithm, music composition by artificial intelligence, and poetry creation by artificial intelligence, which are all created by computer as a creative tool under the impetus of artificial intelligence digital service. It is a combination of human creativity and human writing design code.