A Review of Genetic Understanding and Amelioration of Edible<i>Allium</i>Species

Malik, Geetika; Dhatt, Ajmer Singh; Malik, Ajaz Ahmad

doi:10.1080/87559129.2019.1709202

Cited by 6 publications

(3 citation statements)

References 184 publications

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“…Specifically, shallot bulbs are used to craft functional foods with augmented therapeutic efficacies, which are attributed to the presence of flavor precursors within their cellular matrix ( Raeisi et al, 2016 ; Golubkina et al, 2019 ; Wenli et al, 2019 ). The flavor precursor substances within the cellular matrix of shallots, such as S-alk(en)yl cysteine sulfoxide compounds, catalyze enzymes such as alliinase and lachrymatory factor synthase; they also release organic sulfides in conjunction with other bioactive compounds like flavonols and phenols ( Malik et al, 2021 ), thereby imbuing shallot bulbs with distinct antioxidant and anti-inflammatory properties. The regulation of the Nrf2/HO-1 antioxidant signaling pathway by SSP, which diminishes oxidative damage to vascular endothelial cells, is facilitated by the presence of isoflavones such as daidzein and glycitein ( Jinzhou et al, 2021 ).…”

Section: Introductionmentioning

confidence: 99%

Decoction derived from Allium ascalonicum L. bulbs and Sojae Semen Praeparatum alleviates wind-cold-type common cold via Nrf2/HO-1 pathway and modulation of Lactobacillus murinus level

Jiang,

Wei,

Zhou

et al. 2024

Front. Pharmacol.

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BackgroundCong-Chi decoction (CCD) is made using Allium ascalonicum L. (shallot) bulbs and Sojae Semen Praeparatum (SSP). Shallot bulbs and SSP are both used regularly in traditional Chinese medicine; however, there are no recent pharmacological studies on their synergistic effects. Despite their roles in the treatment of the common cold for thousands of years, their pharmacological mechanisms of action against wind-cold-type common cold are yet to be explored comprehensively.MethodsA mouse model was standardized using wind-cold modeling equipment to study the anti-inflammatory, antioxidant, and antiapoptotic effects of CCD. Then, 16S rRNA sequencing was employed to analyze the association between Lactobacillus murinus and changes in body temperature. Additionally, the antipyretic effects of L. murinus were validated via animal experiments.ResultsThe results indicate that CCD improves the symptoms of wind-cold by reducing fever, levels of pro-inflammatory factors, and cellular apoptosis, as well as increasing the blood leukocyte and lymphocyte counts, thereby alleviating lung tissue damage. The effects of CCD are mediated by upregulation of pulmonary Nrf2 and HO-1 expressions, thereby reducing oxidative damage in the lungs, in addition to other anti-inflammatory mechanisms. Furthermore, CCD increases the abundance of L. murinus in the intestinal tract. The animal experiments confirm that L. murinus ameliorates fever in mice.ConclusionCCD exhibits remarkable antioxidant and anti-inflammatory properties for effectively treating wind-cold-type common cold. Furthermore, its regulatory effects on L. murinus represent a novel mechanism for product development.

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Section: Introductionmentioning

confidence: 99%

Decoction derived from Allium ascalonicum L. bulbs and Sojae Semen Praeparatum alleviates wind-cold-type common cold via Nrf2/HO-1 pathway and modulation of Lactobacillus murinus level

Jiang,

Wei,

Zhou

et al. 2024

Front. Pharmacol.

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“…Allium vegetables, including garlic, onion and shallot, are widely used as herbal supplements ( 2 ). Known as bulb crops, they make up specialized culinary ingredients owing to their characteristic aroma arising from organic sulfur compounds released from the enzymatic breakdown (by allinase and lachrymatory factor synthase) of the flavor precursors [ S -alk(en)yl cysteine sulfoxide compounds] found in their cells ( 3 ). Sulfur compounds released from their decomposition and other bioactive compounds (e.g., flavonols and other phenols) exert prophylactic and curative properties against many human ailments like microbial infections, carcinogenesis and degenerative diseases.…”

Section: Introductionmentioning

confidence: 99%

Therapeutic Uses and Pharmacological Properties of Shallot (Allium ascalonicum): A Systematic Review

et al. 2022

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BackgroundShallot (Allium ascalonicum L.) is a traditional plant species used throughout the world both for culinary purposes and as a folk remedy. To date (i.e., April 2022), there is no report on the main pharmacological activities exerted by shallot preparations and/or extracts.Scope and ApproachThe aim of this study was to comprehensively review the pharmacological activities exerted by shallot, with rigorous inclusion and exclusion criteria based on the scientific rigor of studies. Prisma guidelines were followed to perform the literature search.Key Findings and ConclusionsThe literature search yielded 2,410 articles of which 116 passed the required rigorous criteria for inclusion in this review. The extracts exert a potent antioxidant activity both in vitro and in vivo, as well as a strong inhibitory capacity on various pathogens with relevant implications for public health. Moreover, shallot can be used as adjuvant therapy in cardiovascular diseases, diabetes, cancer prevention, and other non-communicable diseases associated with inflammatory and oxidative pathways. Future studies investigating the chemical composition of this species, as well as the molecular mechanisms involved in the empirically observed pharmacological actions are required.

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“…Genetics of nutraceutical quality in onion is still not explored due to attention being focused mainly on horticultural traits including disease resistance, storability, growth yield, and bolting etc. [ 10 ]. Phenolics and flavonoids are major classes of phytochemicals which impart color, taste and texture.…”

Section: Introductionmentioning

confidence: 99%

Nutraceutical profiling of elite onion germplasm and breeding hybrids with improved nutraceutical quality

et al. 2022

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Onion (Allium cepa L) is a major reservoir of important nutraceutical ingredients. Herein, nutraceutical profiling of elite germplasm was assessed and hybrids with improved nutraceutical quality were selected. The nutraceutical components were screened through Fourier Transform Infrared Spectroscopy (FTIR) analysis (scan range 4000-400cm-1) followed by spectrophotometric/colorimetric quantification in oven dried bulb samples. Line × Tester (L×T) analysis was used to identify potential hybrids with better nutraceutical quality. Based on common functional groups obtained from FTIR analysis, as well as bulb color, the onion genotypes were categorized into six groups viz., white, yellowish brown, light brown, dark brown, brown and purplish brown. Results indicated that the purplish brown, yellowish brown and dark brown genotypes had maximum concentration of pyruvic acid, total flavonoids and total phenolic content, while vitamin C content showed weak association with color pigmentation. The onion variety ‘Onion Swat’ contained the highest level of pyruvic acid (17.18 μM) and ‘MKS8823GO’ had the highest vitamin C content (13.83mg/100mL). The L×T analysis revealed that out of 35 crosses, ‘MKS-77127 × Onion Swat’ and ‘MKS-77127 × MKS777’ were the best hybrids with improved nutraceutical quality. Further, observations for specific combining ability, general combining ability, genetic versus environmental variance, heritability and heterosis indicated that the studied parameters were genetically inherited and could be improved significantly by adopting an appropriate breeding strategy.

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A Review of Genetic Understanding and Amelioration of EdibleAlliumSpecies

Cited by 6 publications

References 184 publications

Decoction derived from Allium ascalonicum L. bulbs and Sojae Semen Praeparatum alleviates wind-cold-type common cold via Nrf2/HO-1 pathway and modulation of Lactobacillus murinus level

Decoction derived from Allium ascalonicum L. bulbs and Sojae Semen Praeparatum alleviates wind-cold-type common cold via Nrf2/HO-1 pathway and modulation of Lactobacillus murinus level

Therapeutic Uses and Pharmacological Properties of Shallot (Allium ascalonicum): A Systematic Review

Nutraceutical profiling of elite onion germplasm and breeding hybrids with improved nutraceutical quality

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