A Review of Foods of Plant Origin as Sources of Vitamins with Proven Activity in Oxidative Stress Prevention according to EFSA Scientific Evidence
María Ciudad-Mulero,
Laura Domínguez,
Patricia Morales
et al.
Abstract:Beyond their nutritional benefits, vitamins could decrease the risk of chronic diseases due to their potent antioxidant capacity. The present work is aimed at reviewing the state of the art regarding (1) the vitamins involved in oxidative stress prevention in accordance with the requirements established by the European Food Safety Authority (EFSA) and (2) the foods of plant origin that are sources of those vitamins and have potential benefits against oxidative stress in humans. According to the European regula… Show more
“…When discussing fat-soluble vitamins, we should also mention vitamins A and E, with the latter comprising tocopherols and tocotrienols. Dietary sources of vitamin E include nuts, almonds, plant oils (especially olive oil), and sprouts [ 59 ]. Although there is no available research indicating the anti-cancer effects of vitamin E on HCC development or progression, its anti-inflammatory properties are utilized in the treatment of liver steatosis and inflammation.…”
Section: Vitamins and Trace Elements As Supportive Elements In The Pr...mentioning
Hepatocellular carcinoma (HCC) is diagnosed annually in nearly a million people worldwide, with approximately half of them being diagnosed at an advanced stage of the disease. Non-infectious risk factors for the development of HCC include an unbalanced lifestyle, including poor dietary choices characterized by a low intake of antioxidants, such as vitamins E and C, selenium, and polyphenols, as well as an excessive consumption of energy and harmful substances. Repeated bad dietary choices that contribute to an unbalanced lifestyle lead to the accumulation of fatty substances in the liver and to it entering an inflammatory state, which, without intervention, results in cirrhosis, the main cause of HCC. This review of the English language literature aims to present the food components that, when included in the daily diet, reduce the risk of developing HCC, as well as identifying foods that may have a carcinogenic effect on liver cells.
“…When discussing fat-soluble vitamins, we should also mention vitamins A and E, with the latter comprising tocopherols and tocotrienols. Dietary sources of vitamin E include nuts, almonds, plant oils (especially olive oil), and sprouts [ 59 ]. Although there is no available research indicating the anti-cancer effects of vitamin E on HCC development or progression, its anti-inflammatory properties are utilized in the treatment of liver steatosis and inflammation.…”
Section: Vitamins and Trace Elements As Supportive Elements In The Pr...mentioning
Hepatocellular carcinoma (HCC) is diagnosed annually in nearly a million people worldwide, with approximately half of them being diagnosed at an advanced stage of the disease. Non-infectious risk factors for the development of HCC include an unbalanced lifestyle, including poor dietary choices characterized by a low intake of antioxidants, such as vitamins E and C, selenium, and polyphenols, as well as an excessive consumption of energy and harmful substances. Repeated bad dietary choices that contribute to an unbalanced lifestyle lead to the accumulation of fatty substances in the liver and to it entering an inflammatory state, which, without intervention, results in cirrhosis, the main cause of HCC. This review of the English language literature aims to present the food components that, when included in the daily diet, reduce the risk of developing HCC, as well as identifying foods that may have a carcinogenic effect on liver cells.
“…The growth and resilience of chickens to oxidative stress are influenced by the antioxidant properties of riboflavin and its role in protein synthesis. Numerous investigations have shown that riboflavin is required for optimum hatchability ( Ciudad-Mulero et al, 2023 ; Mahmudiono and Haliman, 2023 ). The coenzymes flavin adenine dinucleotide and flavin mononucleotide, which are required for numerous redox actions in significant metabolic processes like the mechanism of the antioxidant system and the production of energy, require riboflavin ( Lienhart et al, 2013 ; Kanwal et al, 2024 ).…”
Section: Introductionmentioning
confidence: 99%
“…Riboflavin plays an essential part in the antioxidant system. Its involvement in aerobic cell oxidation processes is particularly significant ( Ciudad-Mulero et al, 2023 ). Glutathione disulfide is converted to reduced glutathione ( GSH ) by the enzyme glutathione reductase, which relies on flavin adenine dinucleotides.…”
OBJECTIVE: This study aimed to investigate the effects of six weeks of continuous training and Nutrition Bio-shield (NBS) Superfood Supplementation on the state of oxidative stress by the expression of Nrf2, NOX4, superoxide dismutase, and malondialdehyde genes in the lungs of rats after methamphetamine withdrawal. METHODS: Forty male Wistar rats were randomly divided into five groups (n = 8, per group), undergoing methamphetamine administration (six weeks, 5 mg/kg ip, and once per day) followed by a 21-day withdrawal period. The rats were supplemented NBS superfood at a dosage of 25 g/kg per day for six weeks. The training protocol was 30 minutes of daily continuous training (treadmill running), five days a week for six weeks. The regimen escalated from a pace of 3 m/min for the initial 5 minutes, to 5 m/min for the following 5 minutes, culminating at 8 m/min for the remainder of the session, all at a 0° incline. A one-way analysis of variance was performed to analyze the gene expression of Nrf2, NOX4, MDA, and SOD in the lungs tissue of rats. RESULTS: The results indicated that, in the experimental groups which underwent continuous training and NBS Superfood supplementation, the expression of the Nrf2 gene exhibited a significant elevation compared to the control group (P < 0.05), while the NOX4, MDA, and SOD genes expression exhibited a significant decline in comparison to the control group (P < 0.05). CONCLUSION: In general, both exercise interventions and NBS superfood supplementation, when employed separately or in combination after methamphetamine withdrawal, can enhance the state of oxidative stress in the lung.
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