A review of dosimetric impact of implementation of model-based dose calculation algorithms (MBDCAs) for HDR brachytherapy

Yousif, Yousif; Osman, Alexander F. I.; Halato, Mohammed A.

doi:10.1007/s13246-021-01029-8

Cited by 2 publications

(2 citation statements)

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“…Several authors have investigated how the TG-186 model would influence dose calculation [ 7 , 8 ] in order to understand clinical impact. As reported by Boman et al .…”

Section: Purposementioning

confidence: 99%

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Dosimetric impact of applying a model-based dose calculation algorithm for skin cancer brachytherapy (interventional radiotherapy)

Placidi,

Fionda,

Rosa

et al. 2023

jcb

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Purpose Brachytherapy (BT, interventional radiotherapy) is a well-established radiotherapy technique capable of delivering high doses to tumors while sparing organs at risk (OARs). Currently, the clinically accepted dose calculation algorithm used is TG-43. In the TG-186 report, new model-based dose calculation algorithms (MBDCA), such as Elekta’s advanced collapsed cone engine (ACE), have been introduced, although their clinical application is yet to be fully realized. This study aimed to investigate two aspects of TG-186: firstly, a comparison of dose distributions calculated with TG-43 and TG-186 for skin tumors; and secondly, an exploration of the impact of using a water bolus on the coverage of clinical target volume (CTV) and OARs. Material and methods Ten treatment plans for high-dose-rate IRT were developed. All plans were initially calculated using the TG-43 algorithm, and were subsequently re-calculated with TG-186. In addition, one of the treatment plans was assessed with both TG-43 and TG-186, using 10 different water bolus thicknesses ranging from 0 to 5 cm. To assess dose variations, the following dose-volume histogram (DVH) parameters were compared: D 2cc and D 0.01cc for OARs, and V 150 , V 100 , V 95 and V 90 for CTV coverage. Results and conclusions The average dosimetric results for CTV and OARs, as calculated by both algorithms, revealed statistically significant lower values for TG-186 when compared with TG-43. The presence of a bolus was observed to enhance CTV coverage for the TG-186 algorithm, with a bolus thickness of 2 cm being the point at which ACE calculations matched those of TG-43. This study identified significant differences in dosimetric parameters for skin tumors when comparing the TG-43 and TG-186 algorithms. Moreover, it was demonstrated that the inclusion of a water bolus increased CTV coverage in TG-186 calculations.

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“…Several authors have investigated how the TG-186 model would influence dose calculation [ 7 , 8 ] in order to understand clinical impact. As reported by Boman et al .…”

Section: Purposementioning

confidence: 99%

“…Several authors have investigated how the TG-186 model would influence dose calculation [7,8] in order to understand clinical impact. As reported by Boman et al [9], TG-43 dosimetry formalism cannot model surface mold treatments in the absence of full scatter conditions within 5% for loading areas larger than approximately 5 × 5 cm 2 .…”

Section: Purposementioning

confidence: 99%