A review of developments and applications of thin‐film microextraction coupled to surface‐enhanced Raman scattering

Abstract

Surface‐enhanced Raman scattering (SERS) greatly expands the applications of Raman spectroscopy and is a promising technique for food safety, environmental analysis, and public safety. Thin‐film microextraction (TFME) provides an efficient sample preparation method for SERS to improve its selectivity and detection efficiency. This review comprehensively describes the development and applications of SERS and TFME, including the history, mechanisim, and active substrate of SERS and the theory, device, forms, and practical applications of TFME. The applications of TFME‐SERS in food safety and environment monitoring are discussed, which could improve their advantages. TFME extracts and enriches the target analytes to eliminate the interfering substance, providing a facial way for SERS to analyze the target analytes in complex matrices. The development of TFME‐SERS technology not only expands the application range of TFME, but greatly improves the anti‐interference ability and detection sensitivity of SERS. Thus, the established methods are fast, convenient, and highly sensitive. This technology is potential to be applied in the on‐site and real‐time detection.

Towards practical and sustainable SERS: a review of recent developments in the construction of multifunctional enhancing substrates

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Silver Nanoparticle-Based Surface-Enhanced Raman Spectroscopy for the Rapid and Selective Detection of Trace Tropane Alkaloids in Food

“…(2) Quantitative identification of trace target in complicated matrix in a high selective and fast manner. Recently, practical applications of SERS are blossoming, and most of them claimed the characteristics of being fast, highly sensitive, highly selective, stable, and easily accessible. − We pointed out previously that in order to realize fast detection, sample pretreatment is normally indispensable, whereas little or no extraction was needed in some cases depending on the nature of the target molecules and the complexity of the sample matrix. Up to now, most of the sample pretreatments for SERS measurement of real samples in aqueous solution simply adopted or modified the one for GC/LC-MS where organic solution is preferred.…”

Functionalized gold nanoparticles for sensing of pesticides: A review

“…Surface-enhanced Raman scattering (SERS) is based on a significant enhancement of Raman signal, typically up to 6 orders of magnitude, from a rough metal surface owing to the electromagnetic and chemical enhancement [ 130 ]. Nanostructured surfaces of gold, silver, or copper are the most common SERS-active substrates.…”