A review of detection methods for the early diagnosis of lung cancer

Davies, Dean F.

doi:10.1016/0021-9681(66)90002-6

Cited by 35 publications

(11 citation statements)

References 70 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…16 False positive and false-negative rates up to 8% and 10%, respectively, have been reported. [18][19][20] The diagnostic accuracy approaches 95% when five sequential samples are submitted, 1 and no significant benefit is seen from additional samples. 1 The sensitivity of PBS is reported to be 35%.…”

Section: Exfoliative Cytology Samplesmentioning

confidence: 99%

“…The optimal number is three samples for the diagnosis of cancer and five samples to exclude cancer. [18][19][20] The diagnostic accuracy approaches 95% when five sequential samples are submitted, 1 and no significant benefit is seen from additional samples. 21 Specimen should be stores at 248C and transferred to the lab immediately b.…”

Section: Exfoliative Cytology Samplesmentioning

confidence: 99%

See 1 more Smart Citation

Committee I: Indications for pulmonary cytology sampling methods

Michael

Hoda

Saqi

et al. 2016

Diagnostic Cytopathology

View full text Add to dashboard Cite

The Papanicolaou Society of Cytopathology has developed a set of guidelines for pulmonary cytology including indications for bronchial brushings, washings and endobronchial ultrasound-guided fine needle aspiration, technical recommendations for cytologic sampling, recommended terminology and classification scheme, recommendations for ancillary testing and recommendations for postcytologic diagnosis management and follow-up. All recommendation documents are based on the expertise of the authors, extensive literature review and feedback from presentations at national and international conferences. This document selectively presents the results of these discussions. The present document summarizes the recommendations for clinical and imaging evaluation of pulmonary lesions along with the indications for cytologic studies regarding these abnormalities. Preprocedural requirements regarding brushing, washing and needle aspiration procedures are discussed also. Diagn. Cytopathol. 2016;44:1010-1023. © 2016 Wiley Periodicals, Inc.

show abstract

Section: Exfoliative Cytology Samplesmentioning

confidence: 99%

Section: Exfoliative Cytology Samplesmentioning

confidence: 99%

Committee I: Indications for pulmonary cytology sampling methods

Michael

Hoda

Saqi

et al. 2016

Diagnostic Cytopathology

View full text Add to dashboard Cite

show abstract

“…Perhaps in order to ensure accuracy in analysis most published reports have included only patients in whom the diagnosis of primary lung cancer has been confirmed by other means, mainly by bronchoscopy or thoracotomy. Davies (1966) lists such data from 25 series extending from the classic paper of Dudgeon and Wrigley (1935) up to 1963, the rates of positivity varying from 42-8 % to 92-7% of the patients examined. Grunze (1960) reviewed 29 similar series with 40% to 90% positives, giving his own figure of 51 % for 3,662 patients tested.…”

Section: Radiological Appearancesmentioning

confidence: 99%

The diagnosis of primary lung cancer with special reference to sputum cytology

Oswald¹,

Hinson²,

Canti³

et al. 1971

Thorax

View full text Add to dashboard Cite

Of 2,545 in-patients with primary lung cancer, pathological proof of the diagnosis was obtained by sputum cytology in 48%, by bronchoscopy in 32%, by biopsy from miscellaneous sites in 12%, and at thoracotomy or necropsy only in 19%. The diagnosis was made solely on clinical and radiological evidence in 8%.One or more satisfactory specimens of sputum from 2,035 patients gave a positivity rate of 59%. When three specimens of sputum were tested the positivity rate was 69% and when four or more were tested, 85%. The maximum false positivity rate was 0-7%. Agreement between the types of malignant cells found in the sputum and in resected or necropsy specimens occurred in 84%. The pathological diagnosis was based solely on sputum cytology in 40% of the patients in whom malignant cells were found in the sputum.The total work of the sputum laboratories was analysed for one year (1967); sputum was examined from 1,598 patients, of whom 266 (17%) had positive results.Of 1,518 patients who had a bronchoscopy, the positivity rate was 53%, and of 524 patients with biopsies from miscellaneous sites the rate was 64%.Sputum cytology, as practised at present, is a very valuable method of diagnosis, but its demands on time and expertise make it unsuitable for general application outside large medical centres. Bartholomew's Hospital and 29 from Brompton Hospital could not be traced.Notes from a total of 2,545 patients were available for study, 913 from St. Bartholomew's and 1,632 from Brompton. There were 2,176 males and 369 (14%) females. One or more specimens of sputum were submitted for cytological investigation from 2,035 (80%) of the patients, bronchoscopy was performed in 1,518 (60%), and biopsies were taken from other sites in 524 (21%). Lung resection was performed in 1,002 (39%) and a further 199 (8%) (1-1%)The miscellaneous group included 10 bronchiolo-623 on 9 May 2018 by guest. Protected by copyright.

show abstract

“…3 In fact, the true incidence of false-positive specimens in this topographic area is difficult to determine because of nonuniform reporting practices. [4][5][6][7][8][9][10] Nevertheless, we believe that no laboratory that aims to make definitive diagnoses can be spared from false-positive results. In this review, we present our personal experiences with that problem, and we review the pertinent literature on false-positive pulmonary cytologic diagnoses.…”

mentioning

confidence: 99%

False‐positive interpretations in respiratory cytopathology: Exemplary cases and literature review

Policarpio‐Nicolas

Wick

2007

Diagnostic Cytopathology

View full text Add to dashboard Cite

Pulmonary cytology has progressed over the past decades because of advancement in imaging studies and increased confidence of pathologists in cytomorphologic diagnosis. It has an overall sensitivity and specificity ranging from *60 to 96%. However, even with the most conscientious laboratories, falsepositive diagnoses of malignancy do occur in respiratory specimens, potentially resulting in unnecessary treatment and morbidity. Selected respiratory cytopathology cases with false-positive diagnoses are presented here, along with a review of pertinent literature and a discussion of possible steps to minimize the problem being considered. Diagn. Cytopathol. 2008;36:13-19. ' 2007 Wiley-Liss, Inc.

show abstract

A review of detection methods for the early diagnosis of lung cancer

Cited by 35 publications

References 70 publications

Committee I: Indications for pulmonary cytology sampling methods

Committee I: Indications for pulmonary cytology sampling methods

The diagnosis of primary lung cancer with special reference to sputum cytology

False‐positive interpretations in respiratory cytopathology: Exemplary cases and literature review

Contact Info

Product

Resources

About