A Review of Destructive Effect of Nano Silver on Human Health, Environment and Animals

Gavanji, Shahin; Larki, Behrouz; Mehrasa, Mohammad

doi:10.12983/ijsres-2013-p231-239

Cited by 4 publications

(4 citation statements)

References 44 publications

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“…Human health effects from AgNP exposure have been reported following dermal or oral administration (Gavanji et al 2013); however, to the best of our knowledge, there are currently no published peer-reviewed studies that discuss the effects of AgNP inhalation in humans. Inhalation studies with animals demonstrated deposition of Ag in the lung and translocation of these nanoparticles to other organs (Anderson et al 2015; Braakhuis et al 2014; Genter et al 2012; Ji et al 2007; Sung et al 2009).…”

Section: Introductionmentioning

confidence: 99%

Size-Dependent Deposition, Translocation, and Microglial Activation of Inhaled Silver Nanoparticles in the Rodent Nose and Brain

Patchin¹,

Anderson²,

Silva³

et al. 2016

Environ Health Perspect

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Background:Silver nanoparticles (AgNP) are present in personal, commercial, and industrial products, which are often aerosolized. Current understanding of the deposition, translocation, and health-related impacts of AgNP inhalation is limited.Objectives:We determined a) the deposition and retention of inhaled Ag in the nasal cavity from nose-only exposure; b) the timing for Ag translocation to and retention/clearance in the olfactory bulb (OB); and c) whether the presence of Ag in the OB affects microglial activity.Methods:Male Sprague-Dawley rats were exposed nose-only to citrate-buffered 20- or 110-nm AgNP (C20 or C110, respectively) or citrate buffer alone for 6 hr. The nasal cavity and OB were examined for the presence of Ag and for biological responses up to 56 days post-exposure (8 weeks).Results:The highest nasal Ag deposition was observed on Day 0 for both AgNP sizes. Inhalation of aerosolized C20 resulted in rapid translocation of Ag to the OB and in microglial activation at Days 0, 1, and 7. In contrast, inhalation of C110 resulted in a gradual but progressive transport of Ag to and retention in the OB, with a trend for microglial activation to variably be above control.Conclusions:The results of this study show that after rats experienced a 6-hr inhalation exposure to 20- and 110-nm AgNP at a single point in time, Ag deposition in the nose, the rate of translocation to the brain, and subsequent microglial activation in the OB differed depending on AgNP size and time since exposure.Citation:Patchin ES, Anderson DS, Silva RM, Uyeminami DL, Scott GM, Guo T, Van Winkle LS, Pinkerton KE. 2016. Size-dependent deposition, translocation, and microglial activation of inhaled silver nanoparticles in the rodent nose and brain. Environ Health Perspect 124:1870–1875; http://dx.doi.org/10.1289/EHP234

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Section: Introductionmentioning

confidence: 99%

Size-Dependent Deposition, Translocation, and Microglial Activation of Inhaled Silver Nanoparticles in the Rodent Nose and Brain

Patchin¹,

Anderson²,

Silva³

et al. 2016

Environ Health Perspect

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“…It is well known established that silver metal is characterized by antibacterial activity, but the mode of its potency to inhibit or delay the bacterial growth was just recently discussed. This antibacterial activity of silver may be due to its ability to entering the microbial cell, causing damage through its binding with the thiol groups (-SH) of the enzymes of microorganisms which can deactivate them [46]. Further inhibitory effect of silver as antibacterial agent increases as its particle size is reduced, since the contact surface area of silver particles with bacteria increased by 10 9 times with the decrease of the particle size from 10 mm to 10 nm [47].…”

Section: Mechanical Propertiesmentioning

confidence: 99%

Synthesis, characterization and in-vitro antimicrobial evaluation of thermally and photostable Schiff base-modified PVC/nanocomposites

Rabie¹,

Ali²,

Khaireldin³

et al. 2020

Egypt. J. Chem.

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Two Schiff base derivatives, 4-[(2, 5-dimethoxy phenylimino)-methyl] phenol, SB1 and 4-[(2-hydroxy benzylidine)-amino] phenolSB2, have been prepared and used as modifiers for polyvinyl chloride (PVC). Chemical modification of PVC was performed using these Schiff base sin presence ofAgNO3to obtain two modified PVC nanocomposite,PVC-SB1/AgNPs and PVC-SB2/AgNPs, and their chemical structures were confirmed by FTIR, 1 H-NMR, 13 C NMR and Mass spectroscopy. Scanning and transmission electron microscopy were performed for the modified polymer nanocomposites. The SEM and TEM micrographs of PVC-SB/AgNPs showed homogeneous surface polymeric matrix with uniform distribution of AgNPs, and their diameters are in the nanoscale. Moreover, thermal and photostabilities as well as mechanical properties of the modified polymer nanocomposites were also investigated. Moreover, mechanical properties of PVC-SB/AgNPs were also investigated. Antimicrobial activity of the modified PVC was evaluated against two Gram +ve bacteria (Bacillus subtitles and Staphylococcus aurous) and two Gram -ve bacteria (Escherichia coli and Pseudomonas aeruginosa) as well as Candida albicans as fungus.

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“…This oil is rich in unsaturated fatty acids and contains omega‐3, omega‐6, omega‐7, and omega‐9. The seven predominant fatty acids of ostrich oil are oleic, palmitic, palmitoleic, linoleic, stearic, alpha‐linolenic, and gamma‐linolenic acids (Basuny et al, 2017 ; Dalvi & Daraei, 2012 ; Gavanji et al, 2013 ; Horbańczuk et al, 2004 ).…”

Section: Introductionmentioning

confidence: 99%

Ostrich oil as a fat substitute in milk‐based infant formula

Dalvi‐Isfahan

Moammernezhad

Tavakoli

2023

Food Science & Nutrition

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In this study, the possibility of replacing vegetable fats with ostrich oil in infant formula (IF) production was investigated. The fatty acid profile, the positional distribution of fatty acids in the triacylglycerols, the cholesterol content, and the physicochemical properties of ostrich oil were determined and compared with breast milk fat and vegetable oils. In the next step, two infant formulas were produced using ostrich oil and vegetable oils and the physicochemical properties, rheological properties, color parameters, and sensory analysis of the resultant powders were compared. The results showed that the predominant fatty acids in ostrich oil are palmitic acid, oleic acid, and linoleic acid which is similar to breast milk fat and vegetable oils. The presence of appropriate cholesterol content in ostrich oil makes it more similar to breast milk fat compared to vegetable fats. Palmitic acid was located at sn‐2 position in 15% triacylglycerol from ostrich fat, which was equal to the amount reported for vegetable fats. The incorporation of ostrich oil in infant formula production showed that there is no statistically significant difference between quality attributes of powder formulated with ostrich oil or vegetable oils. Therefore, ostrich oil can be introduced as a new source of edible oil, and addition of ostrich oil is an effective way to reduce the gap between the composition of breast milk and infant formula.

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A Review of Destructive Effect of Nano Silver on Human Health, Environment and Animals

Cited by 4 publications

References 44 publications

Size-Dependent Deposition, Translocation, and Microglial Activation of Inhaled Silver Nanoparticles in the Rodent Nose and Brain

Size-Dependent Deposition, Translocation, and Microglial Activation of Inhaled Silver Nanoparticles in the Rodent Nose and Brain

Synthesis, characterization and in-vitro antimicrobial evaluation of thermally and photostable Schiff base-modified PVC/nanocomposites

Ostrich oil as a fat substitute in milk‐based infant formula

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