A Review of Cordocentesis: Percutaneous Umbilical Cord Blood Sampling

Peddi, Nikhil Chowdary; Avanthika, Chaithanya; Vuppalapati, Sravya; Balasubramanian, R; Kaur, Jaskaranpreet; N, Chaithanya Datta

doi:10.7759/cureus.16423

Cited by 5 publications

(2 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Cordocentesis is even more invasive than amniocentesis and is associated with more serious fetal risks, including umbilical cord hematoma, fetal bleeding, fetal bradycardia, and fetal death. 8 Red blood cell antigen genotyping in the partner would be inexpensive and would help to prevent unnecessary harms to the pregnant person, including blood draws, time off from work, face-to-face visits for serial ultrasonograms, and invasive fetal blood sampling.…”

Section: Pregnant Peoplementioning

confidence: 99%

An Ethical Argument for Health Insurance Coverage of Paternal Prenatal Genetic Testing

Nguyen

Campo‐Engelstein

Lee

et al. 2022

Obstetrics &Amp; Gynecology

View full text Add to dashboard Cite

Despite evidence-based recommendations from the American College of Obstetricians and Gynecologists and the American College of Medical Genetics to offer prenatal genetic carrier screening for reproductive partners, partner carrier screening or genetic testing is inconsistently covered by pregnant patients' health insurance plans. Health policies that exclude reproductive partners from insurance coverage for prenatal carrier screening or genetic testing contradict multiple ethical principles and can even contribute to adverse maternal–child health outcomes. Incomplete or missing information regarding partner carrier status can lead to costly, invasive, and potentially risky interventions for the pregnant patient that can be avoided by a simple and less expensive blood test in the reproductive partner. Lack of information regarding carrier status also harms the neonate by obviating an opportunity for early detection and treatment of potential medical complications. Insurance policies that exclude coverage for paternal genetic testing perpetuate the disproportionate burdens of pregnancy care and risk shouldered by pregnant people. To rectify these ethical dilemmas, partner carrier screening and genetic testing should be considered and covered as routine components of obstetric health care that are covered by health insurance.

show abstract

Section: Pregnant Peoplementioning

confidence: 99%

An Ethical Argument for Health Insurance Coverage of Paternal Prenatal Genetic Testing

Nguyen

Campo‐Engelstein

Lee

et al. 2022

Obstetrics &Amp; Gynecology

View full text Add to dashboard Cite

show abstract

“…The histological evaluation of the placenta, umbilical cord, and fetal membranes showed no signs of inflammation or pathology. It is useful to perform cordocentesis to determine the values of fetal hemoglobin and reticulocyte count, and, after evaluating the findings, to prescribe the most appropriate treatment method [ 3 , 38 ].…”

Section: Discussionmentioning

confidence: 99%

Parvovirus (B19) Infection during Pregnancy: Possible Effect on the Course of Pregnancy and Rare Fetal Outcomes. A Case Report and Literature Review

Kielaite

Paliulytė

2022

Medicina

View full text Add to dashboard Cite

Infection caused by human parvovirus B19 (B19) often has mild yet wide-ranging clinical signs, with the course of disease usually defined as benign. Particularly prevalent in the population of young children, the virus is commonly transmitted to the parents, especially to susceptible mothers. During pregnancy, particularly the first and second trimesters, parvovirus infection can lead to pathology of the fetus: anemia, heart failure, hydrops, and disorders of physical and neurological development. In severe cases, the disease can result in fetal demise. This article presents a rare case of manifestation of B19 infection during pregnancy. At the 27th week of gestation, a sudden change in fetal movement occurred in a previously healthy pregnancy. The examination of both fetus and the mother revealed newly formed fetal subdural hematoma of unknown etiology and ventriculomegaly. Following extensive examination to ascertain the origin of fetal pathology, a maternal B19 infection was detected. Due to worsening fetal condition, a planned cesarean section was performed to terminate the pregnancy at 31 weeks of gestation. A preterm male newborn was delivered in a critical condition with congenital B19 infection, hydrocephalus, and severe progressive encephalopathy. The manifestation and the origin of the fetal condition remain partially unclear. The transplacental transmission of maternal B19 infection to the fetus occurs in approximately 30% of cases. The main method for diagnosing B19 infection is Polymerase Chain Reaction (PCR) performed on blood serum. In the absence of clinical manifestations, the early diagnosis of B19 infection is rarely achieved. As a result, the disease left untreated can progress inconspicuously and cause serious complications. Treatment strategies are limited and depend on the condition of the pregnant woman and the fetus. When applicable, intrauterine blood transfusion reduces the risk of fetal mortality. It is crucial to assess the predisposing factors of the infection and evaluate signs of early manifestation, as this may help prevent the progression and poor outcomes of the disease.

show abstract

Autopsy findings in a fetus with monosomy 20 mosaicism

Milicevic,

Tadic,

Krasic

et al. 2024

Srp Arh Celok Lek

View full text Add to dashboard Cite

Introduction. Mosaic monosomy 20 is a rare chromosomal aberration, without characteristic clinical features. We present a case of a fetus with monosomy 20 mosaicism revealed after prenatal ultrasound detection of anhydramnios and multiple anomalies. Case outline. The second pregnancy of a 33 years old woman, was terminated at 23rd gestational week, because of the multiple fetal anomalies and anhydramnios, detected by ultrasound. The autopsy of a female fetus revealed multiple congenital anomalies: ventriculomegaly, bilateral choroid plexus cysts, perivascular gliosis in periventricular region of cerebri, hydropericardium, severe cardiomegaly, severe myocardial hypertrophy, hydrothorax, glandular/canalicular stage of fetal lung development, bilateral renal and ureter agenesis (Potter syndrome), bladder aplasia, agenesis of the uterus, fallopian tubes and proximal vagina and valgus deformity of left foot (pes valgus). Fetal growth was adequate for gestational age with no craniofacial dysmorphy or radiographically visible anomalies of the skeleton, without signs of infection. The umbilical cord was too much length for gestational age-48cm. Analysis of fetal karyotype from fetal blood sampling revealed monosomy of chromosome 20 in 10% of analyzed cells in metaphase. Conclusion. Revealing the genetic basis of fetal anomalies is at outmost importance not only for further evaluation of pregnancy, but also for proper genetic informing of patients.

show abstract

A Review of Cordocentesis: Percutaneous Umbilical Cord Blood Sampling

Cited by 5 publications

References 13 publications

An Ethical Argument for Health Insurance Coverage of Paternal Prenatal Genetic Testing

An Ethical Argument for Health Insurance Coverage of Paternal Prenatal Genetic Testing

Parvovirus (B19) Infection during Pregnancy: Possible Effect on the Course of Pregnancy and Rare Fetal Outcomes. A Case Report and Literature Review

Autopsy findings in a fetus with monosomy 20 mosaicism

Contact Info

Product

Resources

About