A Review of Computational Methods to Predict the Risk of Rupture of Abdominal Aortic Aneurysms

Canchi, Tejas; Kumar, Srinivasan Dinesh; Ng, E. Y. K.; Narayanan, Sriram

doi:10.1155/2015/861627

Cited by 40 publications

(19 citation statements)

References 79 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Examples include prior segmentation of the TOF and/or ASL dataset to enhance the vessel-to-background contrast, centerline and bifurcation prediction of the vessels, automated detection of impaired flow behavior (e.g. in stenosis) and risk of rupture in aneurysms [20][21][22][23][24]. Additionally, databases of normal vascular images as well as normal flow behavior can be used to early detect pathological changes.…”

Section: Discussionmentioning

confidence: 99%

Time-Resolved High-Resolution Angiography Combining Arterial Spin Labeling and Time-of-Flight Imaging

2020

View full text Add to dashboard Cite

A strategy to combine two non-contrast-enhanced magnetic resonance angiography techniques is presented. It is based on arterial spin-labeled magnetic resonance imaging to visualize the arterial system at different time points to obtain information about hemodynamic properties in conjunction with a high-resolution time-of-flight angiography acquisition. The temporal information obtained by arterial spin labeling (ASL) is combined with the highly spatial resolved time-of-flight image to obtain information about blood flow. Extracting the information of ASL and time-of-flight-imaging leads to images with high spatial resolution which also give information about the temporal course of blood through the intracerebral vasculature. Furthermore, owing to the properties of ASL, visible venous flow in the time-of-flight images can be suppressed. The behavior of vascular filling (i.e. signal changes in the ASL) is investigated and used for further interpretation of the data. Furthermore, the ASL data were down-sampled to find a minimally needed spatial resolution to combine both image types. Up to 1.6 mm isotropic resolution still showed satisfying results rated by two independent readers. In conclusion, a combination of these two different vascular imaging modalities allows to obtain highly spatial and time-resolved images.

show abstract

Section: Discussionmentioning

confidence: 99%

Time-Resolved High-Resolution Angiography Combining Arterial Spin Labeling and Time-of-Flight Imaging

2020

View full text Add to dashboard Cite

show abstract

“…Recent works suggest that simulations can be used to better predict rupture risk when incorporating WSS compared to a diameter only metric, as the interaction between AAA hemodynamics and vascular biomechanics has a stronger influence on eventual rupture (Taylor and Steinman, 2010;Canchi et al, 2015) (Figures 2I-L). A study using an in vitro model showed that AAA WSS was negatively influenced by intimal thickness (Bonert et al, 2003); the inverse correlation between WSS and wall thickness increases the risk of the rupture.…”

Section: Abdominal Aortic Aneurysmsmentioning

confidence: 99%

Computational Hemodynamic Modeling of Arterial Aneurysms: A Mini-Review

et al. 2020

View full text Add to dashboard Cite

Arterial aneurysms are pathological dilations of blood vessels, which can be of clinical concern due to thrombosis, dissection, or rupture. Aneurysms can form throughout the arterial system, including intracranial, thoracic, abdominal, visceral, peripheral, or coronary arteries. Currently, aneurysm diameter and expansion rates are the most commonly used metrics to assess rupture risk. Surgical or endovascular interventions are clinical treatment options, but are invasive and associated with risk for the patient. For aneurysms in locations where thrombosis is the primary concern, diameter is also used to determine the level of therapeutic anticoagulation, a treatment that increases the possibility of internal bleeding. Since simple diameter is often insufficient to reliably determine rupture and thrombosis risk, computational hemodynamic simulations are being developed to help assess when an intervention is warranted. Created from subjectspecific data, computational models have the potential to be used to predict growth, dissection, rupture, and thrombus-formation risk based on hemodynamic parameters, including wall shear stress, oscillatory shear index, residence time, and anomalous blood flow patterns. Generally, endothelial damage and flow stagnation within aneurysms can lead to coagulation, inflammation, and the release of proteases, which alter extracellular matrix composition, increasing risk of rupture. In this review, we highlight recent work that investigates aneurysm geometry, model parameter assumptions, and other specific considerations that influence computational aneurysm simulations. By highlighting modeling validation and verification approaches, we hope to inspire future computational efforts aimed at improving our understanding of aneurysm pathology and treatment risk stratification.

show abstract

“…Most of the studies regarding renal artery aneurysm (RAA) are in the likes of retrospective studies (Barros et al 2014;Gates et al 2017;Wang et al 2018) or case studies (Canyiğit M et al 2015;Chandra et al 2014;Hwang et al 2011;Maughan et al 2015;Sousa et al 2017;Sultan et al 2016). The FSI study is important to understand the mechanism of rupture of aneurysm at renal artery especially in the case of wide-neck aneurysm (Canchi et al 2015). Relying solely on the diameter of the aneurysm for rupture risk assessment is not sufficient as it been claimed by many researches in other aneurysm conditions (Canchi et al 2015;Farotto et al, 2018;Rissland et al, 2009;Sharzehee et al 2018;Stergiou et al 2019).…”

Section: Introductionmentioning

confidence: 99%

“…The FSI study is important to understand the mechanism of rupture of aneurysm at renal artery especially in the case of wide-neck aneurysm (Canchi et al 2015). Relying solely on the diameter of the aneurysm for rupture risk assessment is not sufficient as it been claimed by many researches in other aneurysm conditions (Canchi et al 2015;Farotto et al, 2018;Rissland et al, 2009;Sharzehee et al 2018;Stergiou et al 2019).…”

Section: Introductionmentioning

confidence: 99%

Stent Porosity Efficiency in Treating Wide-Neck Saccular Renal Artery Aneurysm

Bakar¹,

Abas²,

Razak³

2020

JAFM

View full text Add to dashboard Cite

Renal arteries are the arteries that supply blood to the kidneys. Renal arteries are the arteries that supply blood to the kidneys. Renal artery aneurysm (RAA) is the second most common visceral aneurysm to occur, which accounts for 22% of the visceral aneurysm. In general population, RAA rate of occurrence was only 0.1%. However, due to the extensive used of angiography technique, RAA has been discovered more frequently. Some claimed that the previous rate of incidence should be higher now because of the capability of angiography. The rupture of this aneurysm could result in haemorrhage, kidney lost and mortality. The size of the renal artery which is different compared to other types of arteries such as the abdominal aorta could produce different flow condition when the artery is inflicted with RAA condition. Thus, a thorough analysis is desired as RAA studies are very limited compared to other aneurysm conditions. In this study, the efficiency of the stent porosity was investigated in treating the RAA. Fluid-structure interaction (FSI) simulations and particle image velocimetry (PIV) experiments were the approaches taken to investigate the flow patterns of the blood when the stent of different porosities was placed in the aneurysm entrance. The effect of wall shear stress (WSS), the deformation of the artery and von Mises stress were also observed in determining the possibility of aneurysm rupture. The study found that the placement of stent of different porosities succeeds in providing an obstruction to the blood from circulating inside the aneurysm sac. This in turns reduced the WSS experienced by the aneurysm sac up a significant value of 96%. This reduction is crucial in order to prevent the aneurysm from rupture. Moreover, the placement of the stent provided support to the renal artery and preventing it from experiencing buckling failure. The maximum deformation of the artery reduced by 42% with stent was placed in the renal artery. In fact, the von Mises stress decreased below the threshold limit of 0.5 MPa with the presence of the stent. In addition, the study found that the stent of porosity 80% has a similar impact to the stent of lower porosity in the case of RAA at main renal artery.

show abstract

A Review of Computational Methods to Predict the Risk of Rupture of Abdominal Aortic Aneurysms

Cited by 40 publications

References 79 publications

Time-Resolved High-Resolution Angiography Combining Arterial Spin Labeling and Time-of-Flight Imaging

Time-Resolved High-Resolution Angiography Combining Arterial Spin Labeling and Time-of-Flight Imaging

Computational Hemodynamic Modeling of Arterial Aneurysms: A Mini-Review

Stent Porosity Efficiency in Treating Wide-Neck Saccular Renal Artery Aneurysm

Contact Info

Product

Resources

About