A Review of CO2 Laser-Mediated Therapy for Oral Mucosal Lesions

Abstract

(1) Background: Several studies investigating the clinical outcomes of potentially premalignant oral epithelial lesions treated with CO2 lasers have been published over the last decades. (2) Methods: A systematic research review was performed for studies published between 2011 and 2021 in the PubMed, Science Direct, and Google Scholar databases. (3) Results: Initially, the search identified 52 relevant articles. The primary analysis of the titles and abstracts eliminated 22 articles, leaving 30 articles whose full texts were examined. A total of 22 articles met the inclusion criteria. The studies were classified into 3 categories. (4) Conclusions: After evaluating the results of all the studies included in this review, an initial general statement can be made, namely that CO2 lasers are a treatment option worth taking into consideration when approaching oral mucosal lesions. When compared to other types of lasers used in dental practice, the CO2 laser stands out due to its many advantages.

Laser therapy decreases oral leukoplakia recurrence and boosts patient comfort: a network meta-analysis and systematic review

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CO2 laser vaporisation in treating oral lichen planus: A split‐mouth randomised clinical trial

“…Therefore, there is a need to develop safer and more effective therapies to manage OLP (Alsubhi et al, 2020;Eisen et al, 2005). CO 2 laser is considered the preferred treatment option for superficial mucosal lesions of the oral cavity (Condor et al, 2021;Huang et al, 2015). Due to the high water content in the oral tissue and the ideal absorption of the CO 2 beam by H 2 O molecules, photothermal vaporisation of the tissue occurs with minimal lateral thermal damage (Convissar, 2015).…”

Neuropsychiatric Systemic Lupus Erythematosus: Molecules Involved in Its Imunopathogenesis, Clinical Features, and Treatment

“…Laser treatment/phototherapy: This technique uses light energy to stimulate tissue healing, reduce inflammation, and modulate pain. Laser treatment/phototherapy may be useful for NPSLE patients with skin lesions and oral ulcers [ 200 ]. Collagen is a protein that is essential for wound healing and tissue repair.…”