A Review of Brief Medication-Adherence Instruments Used in Patients with Schizophrenia and Bipolar Disorder

Pomykacz, Brian; Mao, Melissa; Weiss, Roger D.; Teter, Christian J.

doi:10.1080/10673220701650383

Cited by 14 publications

(10 citation statements)

References 18 publications

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“…Precise evaluation and assessment of treatment adherence is difficult in patients with bipolar disorder (Sajatovic et al, 2004). This difficulty is further exacerbated by the lack of agreement about how best to measure adherence (Pomykacz et al, 2007).…”

Section: Resultsmentioning

confidence: 99%

Enhancing medication adherence in patients with bipolar disorder

Berk

Hallam

Colom

et al. 2009

Human Psychopharmacology

123

119

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Enhancement of treatment adherence in bipolar patients is a necessary and promising management component as an adjunct to pharmacotherapy. The current literature on psychosocial interventions that target medication adherence in bipolar disorder points to the possibility of refining the concept of non-adherence and adapting psycho-education to the needs of certain subgroups of people with bipolar disorder. Large scale randomized controlled trials of briefer or more condensed interventions are needed that can inform clinical practice.

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Section: Resultsmentioning

confidence: 99%

Enhancing medication adherence in patients with bipolar disorder

Berk

Hallam

Colom

et al. 2009

Human Psychopharmacology

123

119

View full text Add to dashboard Cite

show abstract

“…Patients in our study were categorized as having a positive (total score ≥ 0) or negative (total score <0) view toward psychiatric medications, consistent with the original scoring method used among patients with schizophrenia (Hogan and Awad, 2000). When used in psychiatric populations, the reliability and validity of the DAI has been shown to be similar to or greater than other commonly used brief medication adherence screening instruments (Pomykacz et al, 2007). …”

Section: Methodsmentioning

confidence: 99%

Medication adherence and attitudes in patients with bipolar disorder and current versus past substance use disorder

Teter

Falone

Bakaian

et al. 2011

Psychiatry Research

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We examined the impact of substance use disorder (SUD) history among patients with bipolar I disorder (BD) in regards to medication-taking behaviors and attitudes. Interviews were conducted with inpatients hospitalized for BD, which included diagnostic instruments and measures of attitudes concerning psychiatric medications. We compared patients with BD and no history of SUD (BD-NH), BD and past history of SUD (BD-PH), and BD and current SUD (BD-C). The primary outcome variable was a standardized medication adherence ratio (SMAR) of [medication taken]/[medication prescribed]. Fifty-four patients with a BD diagnosis participated, which included BD-NH (n=26), BD-PH (n=19), and BD-C (n=9). The SMAR was significantly different among the three groups; post-hoc analyses revealed the SMAR was significantly lower among BD-C (M=0.70) compared to BD-NH (M=0.90) and BD-PH (M=0.97) patients. This finding remained significant after controlling for numerous patient characteristics. Attitudes regarding medications, measured by Drug Attitude Inventory (DAI), were positive among a significantly higher percentage of BD-PH (89.47%) and BD-NH (65.38%) compared to BD-C (44.44%) patients. In conclusion, patients with BD-C demonstrated poor medication adherence and attitudes concerning medication management. Helping patients with BD achieve remission from SUD may lead to a more successful course of BD pharmacotherapy.

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“…Pomykacz et al [ 20 ] reviewed the literature for the presence of structured instruments that have been used in schizophrenic populations. They selected instruments that could be self-administered or used by a clinician with no training required and minimal time commitment.…”

Section: Monitoring Nonadherent Behaviorsmentioning

confidence: 99%

“…Although several scales are available [ 20 ], in reality, most take too much time. What is needed is a short (requiring just a few minutes) assessment tool that requires limited clinical expertise and rater training, such as the BARS [ 21•• ].…”

Section: Monitoring Nonadherent Behaviorsmentioning

confidence: 99%

Tactics and technologies to manage nonadherence in patients with schizophrenia

Glazer

Byerly²

2008

Curr Psychiatry Rep

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The occurrence of treatment nonadherence among patients with schizophrenia is clinically significant. However, studies show that clinicians do not make systematic efforts to identify and monitor it over time. This paper reviews the various tactics for identifying and monitoring adherence behavior. A comprehensive review of published studies comparing typical and atypical antipsychotics in terms of medication adherence yields mixed results at best. Changing forces in the delivery of health care in the United States will promote efforts to improve the recognition of nonadherence in patients with schizophrenia and develop strategies and tactics to decrease the current rates of nonadherence. Such tactics are described in this paper, and emerging best practices are identified. Ultimately, if nonadherence rates are to decrease, it will be necessary to align the incentives of the treater and the treated.

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A Review of Brief Medication-Adherence Instruments Used in Patients with Schizophrenia and Bipolar Disorder

Cited by 14 publications

References 18 publications

Enhancing medication adherence in patients with bipolar disorder

Enhancing medication adherence in patients with bipolar disorder

Medication adherence and attitudes in patients with bipolar disorder and current versus past substance use disorder

Tactics and technologies to manage nonadherence in patients with schizophrenia

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