A review of biomolecules conjugated lanthanide up-conversion nanoparticles-based fluorescence probes in food safety and quality monitoring applications

Sharma, Arumugam Selva; Marimuthu, Murugavelu; Varghese, Amal Wilson; Jizong, Wu; Xu, Jing; Luo, X.; Devaraj, Sabarinathan; Yang, Lan; Li, Huanhuan; Chen, Quansheng

doi:10.1080/10408398.2022.2163975

Cited by 7 publications

(3 citation statements)

References 159 publications

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“…Several recent reviews have comprehensively summarized the research progress of UCNPs, encompassing various aspects such as synthesis and surface modification, [8,13] medical imaging and therapy, [28,29] environmental and food safety detection, [30,31] and so forth. Based on these considerations, this study provides a concise review of the luminescence mechanism of UCNPs, followed by a focused exploration of the optimized design strategies for UCNPs-based sensing systems.…”

Section: Introductionmentioning

confidence: 99%

Upconversion Nanoparticles Based Sensing: From Design to Point‐of‐Care Testing

Wu,

Wei

et al. 2024

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Rare earth‐doped upconversion nanoparticles (UCNPs) have achieved a wide range of applications in the sensing field due to their unique anti‐Stokes luminescence property, minimized background interference, excellent biocompatibility, and stable physicochemical properties. However, UCNPs‐based sensing platforms still face several challenges, including inherent limitations from UCNPs such as low quantum yields and narrow absorption cross–sections, as well as constraints related to energy transfer efficiencies in sensing systems. Therefore, the construction of high‐performance UCNPs‐based sensing platforms is an important cornerstone for conducting relevant research. This work begins by providing a brief overview of the upconversion luminescence mechanism in UCNPs. Subsequently, it offers a comprehensive summary of the sensors’ types, design principles, and optimized design strategies for UCNPs sensing platforms. More cost‐effective and promising point‐of‐care testing applications implemented based on UCNPs sensing systems are also summarized. Finally, this work addresses the future challenges and prospects for UCNPs‐based sensing platforms.

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Section: Introductionmentioning

confidence: 99%

Upconversion Nanoparticles Based Sensing: From Design to Point‐of‐Care Testing

Wu,

Wei

et al. 2024

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“…For instance, Selva Sharma et al placed significant emphasis on the recent trends and progress in the preparation strategies of bioconjugated UCNPs and their potential applications in food safety research. However, they have given little attention to the synthesis methods of UCNPs and have not provided a detailed discussion on the sensing principle of UCNP sensors (Selva Sharma et al, 2022). Abdul Hakeem et al conducted a critical review of recent advancements in rare earth iondoped UCNPs for food safety research.…”

Section: Introductionmentioning

confidence: 99%

Recent advances in rare earth ion‐doped upconversion nanomaterials: From design to their applications in food safety analysis

Li,

Sheng,

Haruna

et al. 2023

Comp Rev Food Sci Food Safe

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The misuse of chemicals in agricultural systems and food production leads to an increase in contaminants in food, which ultimately has adverse effects on human health. This situation has prompted a demand for sophisticated detection technologies with rapid and sensitive features, as concerns over food safety and quality have grown around the globe. The rare earth ion‐doped upconversion nanoparticle (UCNP)‐based sensor has emerged as an innovative and promising approach for detecting and analyzing food contaminants due to its superior photophysical properties, including low autofluorescence background, deep penetration of light, low toxicity, and minimal photodamage to the biological samples. The aim of this review was to discuss an outline of the applications of UCNPs to detect contaminants in food matrices, with particular attention on the determination of heavy metals, pesticides, pathogenic bacteria, mycotoxins, and antibiotics. The review briefly discusses the mechanism of upconversion (UC) luminescence, the synthesis, modification, functionality of UCNPs, as well as the detection principles for the design of UC biosensors. Furthermore, because current UCNP research on food safety detection is still at an early stage, this review identifies several bottlenecks that must be overcome in UCNPs and discusses the future prospects for its application in the field of food analysis.

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“…Compared to these fluorescence donors, upconversion nanoparticles (UCNPs), as a new type of fluorescence material, possess more stable optical properties, longer fluorescence lifetime, less toxicity, and are less prone to photobleaching [15]. Recently, a couple of strategies based on UCNPs have been applied to food safety monitoring, including foodborne bacteria, heavy metals, antibiotics, and pesticide residues [16][17][18][19]. In addition, some novel UCNPs fluorescence biosensors have been developed for foodborne hazardous substances in foodstuff.…”

Section: Introductionmentioning

confidence: 99%

A Novel Nanoplatform Based on Biofunctionalized MNPs@UCNPs for Sensitive and Rapid Detection of Shigella

et al. 2023

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Shigella, a typical and fatal foodborne pathogen with strong infectivity and survivability in foodstuff, demands a simple and sensitive detecting method. In this study, we reported a novel nanoplatform based on biofunctionalized magnetic nanoparticles (MNPs) modified upconversion nanoparticles (UCNPs) for rapid and specific determination of Shigella. Due to base pairing, Shigella aptamer-functionalized horseradish peroxidase (HRP) combined with complementary strand-modified MNPs@UCNPs. In the absence of Shigella, HRP associated with MNPs@UCNPs were magnetically separated, and colorless 3,3′,5,5′-tetramethylbenzidine (TMB) was oxidized into blue oxTMB. The overlap between oxTMB’s absorption peak and MNPs@UCNPs’ emission peak caused the fluorescence quenching at 545 nm. The MNPs@UCNPs fluorescence biosensor was achieved to detect Shigella in 1 h, with a limit of detection of 32 CFU/mL. This work showed a rapid and specific sensing platform and produced satisfactory chicken sample results.

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A review of biomolecules conjugated lanthanide up-conversion nanoparticles-based fluorescence probes in food safety and quality monitoring applications

Cited by 7 publications

References 159 publications

Upconversion Nanoparticles Based Sensing: From Design to Point‐of‐Care Testing

Upconversion Nanoparticles Based Sensing: From Design to Point‐of‐Care Testing

Recent advances in rare earth ion‐doped upconversion nanomaterials: From design to their applications in food safety analysis

A Novel Nanoplatform Based on Biofunctionalized MNPs@UCNPs for Sensitive and Rapid Detection of Shigella

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