“…Antibiotics have thereafter been abused, misused, overused and continually released into natural bodies through WWTPs, which are considered as sinks of major antibiotic reticulation pathways, such as households, aquaculture, healthcare facilities, antibiotic manufacturing facilities, agricultural activities, animal feedlots and slaughterhouses ( Ekwanzala et al, 2018 ; Ben et al, 2019 ; Rodriguez-Molina et al, 2019 ). Correspondingly, numerous reviews have been able to identify the most predominantly consumed or utilised antibiotic categories as: macrolides, sulfonamides, trimethoprim, quinolones, tetracyclines, due to their prevalence in WWTPs and groundwater ( Nnadozie et al, 2017 ; Wang et al, 2020 ; Noor et al, 2021 ) further reports a list of 16 antibiotic families based on their corresponding ARGs extrapolated from analysis of five continents. WWTPs have to capacity to hold, daily, phenomenal volumes of wastewater containing cocktails of chemical contaminants and organic matter, which are consistently biotransformed by denizen microorganisms (both beneficial and harmful).…”