A review of a strategic roadmapping exercise to advance clinical translation of photoacoustic imaging: From current barriers to future adoption

Assi, Hisham; Cao, Rui; Castelino, Madhura; Cox, Ben; Gilbert, Fiona J.; Gröhl, Janek; Gurusamy, Kurinchi; Hacker, Lina; Ivory, Aoife M.; Joseph, James; Knieling, Ferdinand; Leahy, Martin J.; Lilaj, Ledia; Manohar, Srirang; Meglinski, Igor; Moran, Carmel; Murray, Andrea; Oraevsky, Alexander A.; Pagel, Mark D.; Pramanik, Manojit; Raymond, Jason; Singh, Mithun Kuniyil Ajith; Vogt, William C.; Wang, Lihong; Yang, Shufan; Members of IPASC,; Bohndiek, Sarah E.

doi:10.1016/j.pacs.2023.100539

Cited by 17 publications

(5 citation statements)

References 63 publications

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“…Subsequently, these electrical signals are processed and analyzed by a computer system to reconstruct the image of the target object. Photoacoustic imaging offers several advantages over traditional imaging techniques: it enables high-resolution three-dimensional imaging, employs non-contact detection methods, utilizes nanosecond-level laser pulses, and minimizes tissue damage [ 360 ]. In 2016, Zhang et al conducted research that illustrated the superior photoacoustic conversion efficiency of Pdots at 532 nm, surpassing that of gold nanoparticles (GNPs) [ 361 ].…”

Section: Image Formationmentioning

confidence: 99%

Semiconducting polymer dots for multifunctional integrated nanomedicine carriers

Zhang,

Yu,

et al. 2024

Materials Today Bio

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Section: Image Formationmentioning

confidence: 99%

Semiconducting polymer dots for multifunctional integrated nanomedicine carriers

Zhang,

Yu,

et al. 2024

Materials Today Bio

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“…All these issues relate to the requirement for further standardisation, which is currently addressed by the International Photoacoustic Standardisation Consortium. 99 100 …”

Section: Fluoro-d-glucose-pet/ctmentioning

confidence: 99%

Metabolic and molecular imaging in inflammatory arthritis

Noversa de Sousa,

Tascilar,

Corte

et al. 2024

RMD Open

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It is known that metabolic shifts and tissue remodelling precede the development of visible inflammation and structural organ damage in inflammatory rheumatic diseases such as the inflammatory arthritides. As such, visualising and measuring metabolic tissue activity could be useful to identify biomarkers of disease activity already in a very early phase. Recent advances in imaging have led to the development of so-called ‘metabolic imaging’ tools that can detect these changes in metabolism in an increasingly accurate manner and non-invasively.Nuclear imaging techniques such as18F-D-glucose and fibroblast activation protein inhibitor-labelled positron emission tomography are increasingly used and have yielded impressing results in the visualisation (including whole-body staging) of inflammatory changes in both early and established arthritis. Furthermore, optical imaging-based bedside techniques such as multispectral optoacoustic tomography and fluorescence optical imaging are advancing our understanding of arthritis by identifying intra-articular metabolic changes that correlate with the onset of inflammation with high precision and without the need of ionising radiation.Metabolic imaging holds great potential for improving the management of patients with inflammatory arthritis by contributing to early disease interception and improving diagnostic accuracy, thereby paving the way for a more personalised approach to therapy strategies including preventive strategies. In this narrative review, we discuss state-of-the-art metabolic imaging methods used in the assessment of arthritis and inflammation, and we advocate for more extensive research endeavours to elucidate their full field of application in rheumatology.

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“…Unlike mature imaging modalities such as MRI and CT, PA imaging lacks standardized procedures and quality control measures. 121 , 124 This can introduce variability in image quality and interpretation, making it a great challenge to compare results across various studies, institutions, and devices. 7 Establishing education and training procedures for data acquisition and interpretation is imperative.…”

Section: Future and Challengesmentioning

confidence: 99%

“…The reliability, accuracy, and value of PA imaging for specific diagnosis and evaluation need to be thoroughly established through well-designed clinical trials. 124 …”

Section: Future and Challengesmentioning

confidence: 99%

Mini review of photoacoustic clinical imaging: a noninvasive tool for disease diagnosis and treatment evaluation

Liu,

Wang,

et al. 2024

J. Biomed. Opt.

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. Significance Photoacoustic (PA) imaging is an imaging modality that integrates anatomical, functional, metabolic, and histologic insights. It has been a hot topic of medical research and draws extensive attention. Aim This review aims to explore the applications of PA clinical imaging in human diseases, highlighting recent advancements. Approach A systemic survey of the literature concerning the clinical utility of PA imaging was conducted, with a particular focus on its application in tumors, autoimmune diseases, inflammatory conditions, and endocrine disorders. Results PA imaging is emerging as a valuable tool for human disease investigation. Information provided by PA imaging can be used for diagnosis, grading, and prognosis in multiple types of tumors including breast tumors, ovarian neoplasms, thyroid nodules, and cutaneous malignancies. PA imaging facilitates the monitoring of disease activity in autoimmune and inflammatory diseases such as rheumatoid arthritis, systemic sclerosis, arteritis, and inflammatory bowel disease by capturing dynamic functional alterations. Furthermore, its unique capability of visualizing vascular structure and oxygenation levels aids in assessing diabetes mellitus comorbidities and thyroid function. Conclusions Despite extant challenges, PA imaging offers a promising noninvasive tool for precision disease diagnosis, long-term evaluation, and prognosis anticipation, making it a potentially significant imaging modality for clinical practice.

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A review of a strategic roadmapping exercise to advance clinical translation of photoacoustic imaging: From current barriers to future adoption

Cited by 17 publications

References 63 publications

Semiconducting polymer dots for multifunctional integrated nanomedicine carriers

Semiconducting polymer dots for multifunctional integrated nanomedicine carriers

Metabolic and molecular imaging in inflammatory arthritis

Mini review of photoacoustic clinical imaging: a noninvasive tool for disease diagnosis and treatment evaluation

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