A Review of 3D Printing in Orthopedic Oncology

Benady, Amit; Meyer, J. Sam; Freidin, Dor; Ran, Yuval; Golden, Eran; Wong, Kwok Chuen; Dadia, Solomon

doi:10.2217/3dp-2022-0001

Cited by 8 publications

(5 citation statements)

References 77 publications

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“…In addition, our reported PEDSQL scores have shown to be lower than those of healthy children in Egypt, but similar to the mean scores of Egyptian children with chronic conditions [30]. This deviance from the healthy population emphasizes the need for the evolving advanced surgical techniques and individualized tools that are being introduced in orthopedic oncology [52,53].…”

Section: Responses and Different Characteristicssupporting

confidence: 76%

Cross-cultural adaptation and validation of a self-reporting tool to assess health-related quality of life for Egyptians with extremity bone sarcomas in childhood or adolescence.

Farid

Chun

Hassanain

et al. 2023

Preprint

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Purpose Our study pursued cross-cultural adaptation, and validation of the pediatric Toronto Extremity Salvage Score (pTESS) and Toronto Extremity Salvage Score (TESS) to assess the functional outcome for Egyptian children and adult survivors of childhood bone cancer. Mental domains were added to allow the evaluation of health-related quality of life (HRQOL) Methods The internal consistency and test-retest reliability of the studied forms were assessed. For convergent validity, correlations between scores of the generic Pediatric Quality of Life Inventory (PEDSQL 4.0) and pTESS /TESS scores were reported. Exploratory Factor Analysis (EFA) was feasible for pTESS-leg; due to the insufficient samples, only the average inter-item correlation coefficients were reported for the remaining versions. Results Out of 233 participants, 134 responded to pTESS leg, 53 to TESS-leg, 36 to pTESS-arm, and only 10 to TESS-arm. All versions showed excellent internal consistency (Cronbach’s alpha > 0.9), good test-retest reliability (Intra-class coefficients > 0.8), moderate to strong correlations with PEDSQL, and acceptable average inter-item correlation coefficients (≥ 0.3). In the EFA, all mental items were loaded on one separate factor with factor loadings exceeding 0.4. Chemotherapy, primary surgery within one year, or tibial tumors showed significantly inferior pTESS/TESS scores in lower extremities. Conclusion The Egyptian pTESS and TESS are valid and reliable self-reporting tools for assessing the functional outcome following surgeries of extremity bone sarcomas. The mental domains enabled the assessment of the overall health status in our population. Future studies should include larger sample size and evaluate the ability of pTESS/TESS to track progress over time.

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Section: Responses and Different Characteristicssupporting

confidence: 76%

Cross-cultural adaptation and validation of a self-reporting tool to assess health-related quality of life for Egyptians with extremity bone sarcomas in childhood or adolescence.

Farid

Chun

Hassanain

et al. 2023

Preprint

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“…In addition, our reported PedsQL scores have been shown to be lower than those of healthy children in Egypt but similar to the mean scores of Egyptian children with chronic conditions [ 32 ]. This deviance from the healthy population emphasizes the need for the evolving advanced surgical techniques and individualized tools that are being introduced in orthopedic oncology for the aim of enhanced outcomes [ 63 , 64 ].…”

Section: Discussionmentioning

confidence: 99%

Cross-cultural adaptation and validation of a self-reporting tool to assess health-related quality of life for Egyptians with extremity bone sarcomas in childhood or adolescence

Farid¹,

Chun²,

Hassanain³

et al. 2023

Health Qual Life Outcomes

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Background Validated self-reporting tools are required to evaluate the functional outcome and health-related quality of life (HRQOL) for those who had extremity bone sarcomas in their childhood or adolescence. Our study pursued cross-cultural adaptation and validation of the pediatric Toronto Extremity Salvage Score (pTESS) and Toronto Extremity Salvage Score (TESS) to assess the functional outcome for Egyptian children and adult survivors following surgeries of extremity bone sarcomas. In the modified versions of pTESS and TESS, mental domains were added to allow the evaluation of HRQOL using a specific instrument for childhood bone cancer. Methods The internal consistency and test–retest reliability of the studied forms were assessed with Cronbach’s alpha and Intra-class coefficients (ICC), respectively. For convergent validity, correlations between scores of the generic Pediatric Quality of Life Inventory (PedsQL 4.0) and pTESS /TESS scores were reported. Factor Analysis was feasible for pTESS-leg; due to the insufficient samples, only the average inter-item correlation coefficients were reported for the remaining versions. Results Out of 233 participants, 134 responded to pTESS-leg, 53 to TESS-leg, 36 to pTESS-arm, and only 10 to TESS-arm. All versions showed excellent internal consistency (Cronbach’s alpha >0.9), good test–retest reliability (ICC >0.8), moderate to strong correlations with PedsQL, and acceptable average inter-item correlation coefficients (≥0.3). Three factors were extracted for the pTESS-leg, in which all mental items were loaded on one separate factor with factor loadings exceeding 0.4. Active chemotherapy, less than one year from primary surgery, or tibial tumors were associated with significantly inferior pTESS/TESS scores in the lower extremity group. Conclusion The Egyptian pTESS and TESS are valid and reliable self-reporting tools for assessing the functional outcome following surgeries for extremity bone sarcomas. The modified pTESS and TESS versions, which include additional mental domains, enabled the assessment of the overall health status of our population. Future studies should include a larger sample size and evaluate the ability of pTESS/TESS to track progress over time.

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“…The second case involves designing a customized cranial implant as a virtual model for preoperative planning to mitigate potential patient issues. Adequate preoperative planning is essential for elective surgery [24][25][26][27], such as technical planning for the distal phalanx finger and the skull bone required before surgery. Computed Tomography (CT) scans create three-dimensional (3D) reconstructions of the patient's anatomy in a virtual environment.…”

Section: Introductionmentioning

confidence: 99%

Design and manufacturing of custom 3D printed bone implants

Neamah,

Al-Kindi,

Al-Kindi

2024

ETJ

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In medical surgery, a customized implant is often required to meet surgical requirements, especially in cases with complicated or traumatic deformities. The emerging techniques of additive manufacturing, e.g., 3D printing, may help provide a quick response to such needs, provided that a valid approach capturing required implant shape data is generated and processed to better suit 3D printing. Different materials, including biocompatible polymer and metal, may suit medical-surgical applications. In this paper, an investigation is conducted to assess 3D printing technology use as part of a full system, from capturing implant shape data to producing the customized implant. The investigation is supported by experimental studies of medical cases. The first case aimed to produce shatter-related finger distal phalanx implants, whereas the second aimed to design and reconstruct a suitable cranial implant for a patient with a left frontoparietal skull lesion. For these cases, the study has adopted a scenario based on CT scans to generate the required implant shape data; hence using DICOM format. The captured data from the two cases are processed using a developed systematic processing approach to generate the final design of the required customized implants. The designs are then converted into suitable manufacturing codes for 3D printed plastic and metal prototypes enabling the assessment of the technique utilizing the facilities of UrukTech Company in Baghdad, Iraq, and Sohar University in Oman. Results show that the developed approach, from data capture to 3D printed implants, has succeeded in addressing the need for customized implants. For instance, the accuracy of the cranial implant was confirmed dimensionally, aiding in restoring structures, appearance, and psychological stability. The design and manufacturing of custom 3D-printed bone implants represent a significant advancement in medical technology and orthopedics, provided that biocompatible materials are used. Therefore, the technique may be adopted in the near future to serve the medical surgery field. The developed approach in this study encompasses several key ideas, contributions, and significant results, including creating patient-specific bone implants by utilizing medical imaging and 3D printing. Hence, the developed approach enables the creation of complex implant geometries that otherwise would be challenging to manufacture.

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A Review of 3D Printing in Orthopedic Oncology

Cited by 8 publications

References 77 publications

Cross-cultural adaptation and validation of a self-reporting tool to assess health-related quality of life for Egyptians with extremity bone sarcomas in childhood or adolescence.

Cross-cultural adaptation and validation of a self-reporting tool to assess health-related quality of life for Egyptians with extremity bone sarcomas in childhood or adolescence.

Cross-cultural adaptation and validation of a self-reporting tool to assess health-related quality of life for Egyptians with extremity bone sarcomas in childhood or adolescence

Design and manufacturing of custom 3D printed bone implants

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