A Review of 244 Orbital Tumors in Japanese Patients During a 21-Year Period: Origins and Locations

Ohtsuka, Kenji; Hashimoto, Masato; Suzuki, Yasuo

doi:10.1007/s10384-004-0147-y

Cited by 139 publications

(102 citation statements)

References 8 publications

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“…2,5,9 The frequency and distribution of tumor diagnosis and their association with age is in accordance with past studies that too have demonstrated a relatively higher frequency of vascular and lacrimal gland tumors among operable orbital neoplasms. 3,5,[9][10][11][12][13] Proptosis is the commonest presentation reported in orbital tumors, and in our series the mean proptosis is quite similar to previous data. 3,14,15 In effect, our series is a universally representative sample of orbital tumors.…”

Section: Discussionsupporting

confidence: 90%

Visual function alterations in orbital tumors and factors predicting visual outcome after surgery

Singh

Pushker

Bajaj

et al. 2011

Eye

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Purpose To study the effect of orbital tumors on visual functions and highlight the factors predictive of visual outcome after surgery. Methods A prospective interventional study compared visual function parameters and fundus changes, before and after surgery, in eyes having well-defined orbital tumors with the normal fellow eye. These included visual acuity (VA), refractive error, keratometry changes, color vision, Goldmann visual field (GVF), and visual evoked response (VER). Results In total 28 cases (age range 7-56 years), of which the majority of tumors were vascular (46%) and lacrimal (18%) in origin, had a mean VA of 0.54±0.33 in the affected eye, which improved postoperatively to 0.66 ± 0.31 (P ¼ 0.002). The affected eye had a median refractive error of þ 0.00 DS (À2.00 to 5.13), which was significantly more hyperopic than the normal eye (median þ 0.00 DS; range À1.25 to þ 1.63 DS) and normalized postoperatively. Keratometry showed higher astigmatism in the involved eye (P ¼ 0.004). The fundus showed disc pallor, edema, and/or choroidal folds, of which disc edema resolved in all cases after surgery. In all, 40% of the affected eyes had a deficient color vision and this partially improved postoperatively (P ¼ 0.25). GVF had abnormalities in 10 cases, half of which normalized postoperatively (P ¼ 0.04). The VER of affected eyes had a mean amplitude of 8.91 ± 4.59 lv and latency of 116.3 ± 14.7 ms, with improvement after surgery (P ¼ 0.005 and 0.001, respectively). Conclusion Orbital tumors adversely affected visual functions. The presenting acuity depended on disc changes, color vision abnormalities, and prolonged VER latency. The postoperative VA depended on VA at presentation, amount of proptosis, degree of hyperopia, and clinically significant VER abnormalities.

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Section: Discussionsupporting

confidence: 90%

Visual function alterations in orbital tumors and factors predicting visual outcome after surgery

Singh

Pushker

Bajaj

et al. 2011

Eye

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“…It accounts for 0.01 % of all lymphomas but for 5% to 10% of all orbital tumors. 1,2 The clinical manifestations are non-specific. Radiological diagnoses are only seen in various case reports.…”

Section: Introductionmentioning

confidence: 99%

CT and MRI features of Primary Orbital Lymphoma: review of 14 cases

et al. 2011

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Objective: To assess the computed tomography (CT) imaging and magnetic resonance imaging (MRI) features of primary orbital lymphoma and to establish a differential diagnosis. Material & Methods:Fourteen patients (9 male and 5 female) suffering from primary orbital lymphoma underwent CT scanning with and without contrast. Pre-and post-contrast MRI scans were performed in 10 patients. Their ages ranged from 1.5 to 65 years (average age: 36 years). The course of diseases varied from 2 months to 16 years. Results:The diagnosis was confirmed pathologically in all cases. Lesions were bilateral in 4 cases and unilateral in 10 cases. Periorbital preseptal tissues were involved mainly in the upper lateral quadrant of the orbit. Focal masses were observed in 5 patients. Lesions that infiltrated the lacrimal gland, adjacent extraocular muscles and intraorbital tissues, along with the extraocular muscles, were found in other patients. The tumors that had advanced into intraorbital tissues and had involved extraocular muscles, displayed either a "casting sign" or a "ring sign". Isodense soft-tissue masses with clear demarcation were found on plain CT film and lesions displayed low to intermediate signal intensity on T1-weighted MRI and relatively low or high signal intensity on T2-weighted MRI. The lesions demonstrated homogeneously marked enhancement on CT and MRI with contrast medium. Conclusion:CT imaging and MRI -particularly MRI -can demonstrate the location, configuration, inner structure and characteristic manifestations of the orbital lymphomas. This may assist the pre-operative diagnosis of these lesions.

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“…Two third of the benign tumors and one third malignant tumors occur in the orbit [1]. The orbital tumor has low incidence of diagnosis and there are several complications after treatment or operation such as cosmetic problems, severe ophthalmological deficit with loss of vision and eye movement [2]. It is most important to obtain maximum information about the orbital tumor prior to deciding the appropriate treatment strategy in the order to manage post-operative complications [3][4][5].…”

Section: Introductionmentioning

confidence: 99%

Valuation of Four-Quadrant Location Method in Diagnosis and Differential Diagnosis of the Orbital Tumor by Comparison Study Combining CT and MRI with Pathology

Akter¹,

Hasan²,

Sana³

et al. 2017

J Pain Relief

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Purpose: To valuate four-quadrant location method in diagnosis and differential diagnosis of the orbital tumor by comparison study combining CT and MRI with pathology. Materials and methods:Data of 87 patients (44 female and 43 males), aged 1 to 84 years were recruited in this study, including the computed tomography(CT), Magnetic resonance imaging (MRI), and histopathology diagnosis. All orbital tumors were verified radiologically and pathologically in the Hospital of Jinggangshan University from Sep-2008 to April-2016 patients underwent CT scanning (31 Conventional CT and 18 dynamic contrast enhancements CT) and 38 patients underwent MR Imaging (35 dynamic contrast enhancement MRI and 3 conventional MRI). The clinical data were retrieved from the medical record. We classified the orbital region according to four-quadrant and eight-space (FQES) division and traditional muscleconal division with center point of optic nerve. Results:Among the 87 cases of the orbital tumors, 70 cases (80.45%) were orbital benign tumors and 17 cases (19.54%) were malignant tumors. Regarding the location of the orbit, 41 lesions (47.12%) were in superolateral, 18 lesions (20.68%) were in inferolateral, 16 lesions (18.39%) were in inferomedial, 8 lesions (9.19%) were in superomedial, 3 lesions (3.44%) were in globe, 1 lesion (1.14%) was in optic nerve. The most common tumors are hemangiomas (total 36 cases: 12 in inferolateral, 8 in inferomedial, 9 in superolateral, 7 in superomedial) and 9 cases of pleomorphic adenoma were in superolateral, 9 cases of dermoid cyst ( 7 in superolateral and in 2 inferomedial), 5 cases of inflammatory pseudotumor (4 in superolateral and 1 in inferomedial), 7 cases of lymphoma (3 in superolateral, 2 in inferolateral and 2 in inferomedial ), 3 cases of adenoid cystic carcinoma in superolateral, 3 caese solitary fibrous tumor ( 2 in suprolateral and 1 in inferomedial), 3 cases lipoma (1 in superomedial, 1 in superolateral and 1 in inferolateral), 2 cases choroidal melanoma were in globe, 1 case of metastasis in superolateral, 1 case of meningioma in optic nerve, 1 case of malignant melanoma was in superolateral. The orbital tumors appeared in orbit with mostly regular, oval and rounds shape, well defined margin. The size ranged from 0.8 mm × 4.5 cm to 4.5 cm × 2.0 cm. The CT revealed iso-density in 22, slightly high-density in 15, mixed density in 6, low density in 5 and high density in 1 lesion. Among them, 18 were contrast enhancements. On T1WI image, the MRI revealed low signal intensity in 23 cases, slightly low signal in 4 cases, iso signal intensity in 7 case, high signal intensity in 3 cases, mixed signal intensity in 1 case on T2WI, it revealed high signal intensity in 23 cases, slightly high intensity in 7 cases, low signal intensity in 4 cases, iso signal intensity in 3 cases, mixed signal intensity in 1 case. Among them, 35 contrast enhancement MRI and 3 were non contrast MRI. Benign tumor was diagnosed in 70 patients, of them 34 were male and 36 were female, and the mean age was 45.19 ...

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A Review of 244 Orbital Tumors in Japanese Patients During a 21-Year Period: Origins and Locations

Cited by 139 publications

References 8 publications

Visual function alterations in orbital tumors and factors predicting visual outcome after surgery

Visual function alterations in orbital tumors and factors predicting visual outcome after surgery

CT and MRI features of Primary Orbital Lymphoma: review of 14 cases

Valuation of Four-Quadrant Location Method in Diagnosis and Differential Diagnosis of the Orbital Tumor by Comparison Study Combining CT and MRI with Pathology

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