A Review Article of Lymphedema in Gynecologic Malignancies: A Practical Approach

Abstract

Lymphedema is an unusual and specific type of peripheral edema resulting from obstruction or disruption of lymphatic system. The present review was conducted on PubMed, UpToDate, and ClinicalKey databases before 2016. The keywords included lymphedema or leg edema AND advanced malignancy. The primary review revealed 104 full text publications, of which 24 relevant articles were selected and another 17 relevant articles from the reference list of the selected articles were added, as well. Practical points in diagnosis and treatment of lymphedema in gynecologic malignancies are presented in the below subtitles: -basic descriptions, classifications, and epidemiology; -clinical presentation and diagnostic tests; -differential diagnosis; -non-surgical management; -surgical management.