“…Estimates of pollution concentrations and personal exposures can also be obtained through physical or mechanistic modeling-based approaches, including atmospheric, indoor/outdoor/personal exposure, and hybrid models (Boothe et al, 2005;Jerrett et al, 2005;Isakov et al, 2006;McConnell et al, 2006;Isakov and Ö zkaynak, 2007;Ö zkaynak et al, 2008); spatial interpolation techniques, for example, kriging or splining methods (Jerrett et al, 2005); and empirical statistical models, such as land-use regression models (Brauer et al, 2002;Jerrett et al, 2005;Ross et al, 2006;Smith et al, 2006). However, these methods can be resource intensive and may impose a significant burden on study participants.…”