A Review (1970-1980) of 28 Presumptive Cases of Syphilitic Uveitis

Vitreitis and movement disorder associated with neurosyphilis and human immunodeficiency virus (HIV) infection: case report

“…McLeish et al also reported a patient with dense vitreitis and chorioretinal disease (2) . Similar to ours, all three patients reported by Kuo et al and the patient described by McLeish et al were HIV positive (2)(3) . Although admittedly speculative, an HIV altered immune system may result in dense vitreitis with little to no visible retinal abnormalities as opposed to the prominent chorioretinitis, seen more commonly in immunocompetent hosts.…”

“…Potential ophthalmic manifestations are many and can aid in pathogen identification; however, isolated vitreitis has rarely been described (1)(2)(3) . Although not infrequent, movement disorders are rarely the predominating abnormality in patients with neurosyphilis (4) .…”

Posterior syphilitic uveitis: clinical characteristics, co-infection with HIV, response to treatment

“…It is an uncommon cause of uveitis (estimated, from 1970 to 1980, to comprise 1.1% of cases [3]). Syphilitic uveitis can include anterior segment findings such as iridocyclitis, as well as posterior segment findings including vitritis, chorioretinitis and optic neuritis [3][4][5].…”

Neuroretinitis in secondary syphilis

“…Spector et al (1981) describe a patient with granulomatous conjunctivitis, confirmed by biopsy. Schlaegel and Kao (1982) found in 1.1% (n = 28) of their patients with uveitis that syphilis was the cause. These was an even distribution between anterior and posterior uveitis, the majority had panuveitis.…”