A retrospective study of salivary gland diseases in 179 dogs (2010–2018)

Abstract

Salivary gland diseases are well characterized in human medicine but are uncommonly reported in dogs. Herein we describe the clinical and pathologic features of 179 canine salivary gland biopsy submissions to the Athens Veterinary Diagnostic Laboratory from 2010 to 2018. The mean age of affected dogs was 8.5 y; no sex or breed predisposition was evident. The main reason for sample submission was regional swelling (107 cases; 59.7%). Extraoral (major) salivary glands were affected in 125 cases (69.8%), and oral (minor) salivary glands were affected in 43 cases (24% of cases). The location of the lesion (extraoral or oral) was not specified in 11 cases (6.1%). The diagnoses included nonspecific sialoadenitis (89 cases; 49.7%), normal salivary gland (42 cases; 23.4%), neoplasia (36 cases; 20.1%), salivary gland lipomatosis (7 cases; 3.9%), necrotizing sialometaplasia (4 cases; 2.2%), and traumatic hemorrhage (1 case; 0.5%). Most cases of sialoadenitis (63 cases), neoplasia (23 cases), and lipomatosis (5 cases), as well as all cases of necrotizing sialometaplasia and the only case of traumatic hemorrhage, affected extraoral glands. Most neoplasms (32 cases, 88.8% of the tumors) were epithelial and malignant, followed by round cell tumors (2 cases; 5.5%), a carcinosarcoma (1 case; 2.7%), and a tumor of undetermined histogenesis (1 case; 2.7%).

Imaging diagnosis: CT findings in bilateral necrotising sialometaplasia of the mandibular salivary glands in a Tibetan Terrier

“…7,9 Histopathological and clinical reports in dogs and cats have been published. 1,[3][4][5][6][7] However, to the authors' knowledge, there are no imaging descriptions of confirmed necrotising sialometaplasia in dogs or cats. 1,[3][4][5][6][7] This study reports the imaging features of cytologically confirmed necrotising sialometaplasia with documented resolution on follow-up assessment.…”

“…This case describes previously unreported computed tomography (CT) features of canine necrotising sialometaplasia, a distinct clinical entity that to date has only been described in histopathological or clinical reports in veterinary patients. [1][2][3][4][5][6][7] This condition is characterised by painful lobular necrosis, fibrosis and squamous metaplasia of the affected salivary glands. 2,8,9 Both spontaneous resolution and response to phenobarbitone treatment have been reported in veterinary patients.…”

Computed tomographic findings in two dogs with chronic unilateral parotid duct ectasia

“…Disorders of the parotid gland are uncommon in dogs and mainly affect the gland itself, rather than the duct. These disorders include hypersialosis, sialolithiasis, parotid sialocele, parotid duct rupture and secondary fistula, sialodenosis, lipomatosis, primary and secondary neoplasia, parotid duct foreign body, trauma, necrotising sialometaplasia, sialoadenitis and parotid duct stenosis with secondary ectasia 1–8 …”

Clinical outcomes of thyroid tumours with concurrent epithelial and mesenchymal components in 14 dogs (2006–2020)

“…In contrast to carcinosarcomas where both components of the tumour are neoplastic, mixed tumours are tumours with distinct concurrent epithelial and mesenchymal neoplastic populations of cells are present, though each individual component can be benign or malignant. Carcinosarcomas are rare in the dog and have been described in the thyroid gland (Buergelt, 1968 ; Fernandez et al., 2008 ; Giuliano et al., 2013 ; Grubor & Haynes, 2005 ; Johnson & Patterson, 1981 ; Mason & Wells, 1929 ; Wells, 1901 , ), mammary gland (Benjamin et al., 1999 , Rasotto et al., 2017 , Canadas et al., 2019 ), lung (Salas et al., 2002 ), eyelid (Hirai et al., 1997 ), salivary gland (Lieske & Rissi, 2020 , Pérez‐Martínez et al., 2000 ) and ceruminous gland (Moisan & Watson, 1996 ).…”