A retrospective study of potential influence factors on Helicobacter pylori infection treatment

Abstract

BackgroundThe high prevalence of Helicobacter pylori (H. pylori) infection has been associated with overcrowding, poor housing, poor sanitation and unclean water supplies in developing countries.MethodsWe assessed records of symptomatic patients attending Southwest Hospital in 2017, collected patients’ information such as age, gender, education levels, income level, number of family members, frequency of hand washing after defecation, past history of gastropathy and so on. Chi square analysis, t-test and Odds Ratio (OR) were used to evaluate the effect of potential factors on treatment effect.ResultsAge, gender, number of family members, follow-up time, type of toilet, water source and past history of gastropathy seemed to be irrelevant to H. pylori infection control. Higher education level was benefit for patients (OR 0.315, 95% CI 0.134-0.741, P=0.008). Less frequency of hands washing after defecation was harmful factors for H. pylori-positive patients’ treatment (OR=3.438, 95% CI 1.679-7.039, P=0.001). Better income status was a protective factor only in Univariate analysis (OR=0.396 95% CI 0.197-0.795, P=0.01).ConclusionA better education background and strict habits of hands washing were both helpful for H. pylori-positive patients’ treatment.