A Retrospective Study of Necrotising Fasciitis

Rekha, Arcot; Annamalai, Radha

doi:10.1177/1534734603002001008

Cited by 4 publications

(10 citation statements)

References 8 publications

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“…In the case series by Taviloglu et al (3) and Rekha and Ravi (5), 79.4% (27 of 34) and 100% (7 of 7), respectively, of mortalities had diabetes. Children and adolescents were included in three of the studies (3, 5, 6). Only Rekha and Ravi (5) delineated the exact number of patients in the pediatric age group (one male aged between 0 and 10 yr and one female aged between 11 and 20 yr), with the greatest number of patients in the 41–50 yr class interval.…”

Section: Discussionmentioning

confidence: 92%

“…Diabetes was identified as a risk factor for increased mortality in the studies outlined in the Table 1(3–6). In the case series by Taviloglu et al (3) and Rekha and Ravi (5), 79.4% (27 of 34) and 100% (7 of 7), respectively, of mortalities had diabetes. Children and adolescents were included in three of the studies (3, 5, 6).…”

Section: Discussionmentioning

confidence: 97%

“…Retrospective case series of patients with NF have reported diabetes mellitus as a comorbidity in 40–70% (3, 4, 10–13). Diabetes was identified as a risk factor for increased mortality in the studies outlined in the Table 1(3–6). In the case series by Taviloglu et al (3) and Rekha and Ravi (5), 79.4% (27 of 34) and 100% (7 of 7), respectively, of mortalities had diabetes.…”

Section: Discussionmentioning

confidence: 98%

“…High mortality rates have been described in case series of adult and pediatric patients with NF (3–6, 9). Extensive tissue damage and systemic toxicity (including multiorgan failure and shock) may occur.…”

Section: Discussionmentioning

confidence: 99%

“…In case series of NF comprising mostly adult patients, diabetes mellitus has been identified as a major risk factor and one that is associated with increased mortality (3–6). NF is much less common in childhood with no previously reported cases associated with type 1 diabetes in children or adolescents identified.…”

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confidence: 99%

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Necrotizing fasciitis in adolescents with poorly controlled type 1 diabetes mellitus: report of two cases

et al. 2007

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Necrotizing fasciitis (NF) is a potentially fatal bacterial infection of the subcutaneous soft tissues. Two cases of polymicrobial NF in adolescents with type 1 diabetes mellitus and poor glycemic control are reported. The perineal region was involved in both cases. One case was precipitated by apparently minimal trauma, the other by high-impact trauma. Diabetes mellitus has been identified as a common comorbidity and predictor of increased mortality in adult patients with NF. The associations between diabetes and the incidence or outcome of NF in children and adolescents are not known. In all cases, early identification and aggressive surgical intervention are important for limiting morbidity and mortality.

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Section: Discussionmentioning

confidence: 92%

Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

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Necrotizing fasciitis in adolescents with poorly controlled type 1 diabetes mellitus: report of two cases

et al. 2007

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Postprocedural Necrotizing Fasciitis: A 10-Year Retrospective Review

Miller

Saadai

Greenstein

et al. 2008

The American Surgeon

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Necrotizing fasciitis (NF) is a severe soft tissue infection, which has a reported 25 per cent to 60 per cent mortality rate. In addition, NF has been reported to occur after invasive procedures. We present a 10-year retrospective study on postprocedural NF and its differences with community-acquired NF. A retrospective study was conducted from 1996 to 2006. Charts were searched using International Classification of Diseases, 9th Revision codes for NF and gas gangrene. Patients who developed NF in the area of their previous procedure without any other inciting cause of the NF were deemed eligible for the study. Eleven patients met eligibility criteria. Seven patients’ initial procedures were elective, whereas four were semiemergent. The median age was 48 years (range, 24–81 years). The time between the initial procedure and operation for NF varied from 3 days to over 3 months. No single laboratory value helped in diagnosing NF. Sixteen different bacteria were isolated from the 11 patients. Ten of 11 patients required multiple débridements. There were four mortalities, three of whom had comorbidities known to predispose to infection. NF is a rare but serious complication after invasive procedures. As a result of important differences that exist between postprocedural and community-acquired NF, we propose that postprocedural NF should be classified in its own subcategory.

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Necrotizing Soft-Tissue Infections in the Feet of Patients With Diabetes: Outcome of Surgical Treatment and Factors Associated With Limb Loss and Mortality

Aragón‐Sánchez

Quintana-Marrero

Lázaro-Martínez

et al. 2009

The International Journal of Lower Extremity Wounds

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The aim of this study was to analyze the outcomes of treatment of necrotizing soft-tissue infections (NSTIs) in the feet of diabetic patients and to determine factors associated with limb salvage and mortality. A retrospective study of a consecutive series of 145 diabetic patients suffering from NSTIs treated in the Diabetic Foot Unit, La Paloma Hospital was done. NSTIs were classified as necrotizing cellulitis if it involved the subcutaneous tissue and the skin, as necrotizing fasciitis if it involved the deep fascia, and as myonecrosis in those cases where muscular necrosis was present. In the necrotizing cellulitis group (n = 109), 8 (7.3%) major amputations were performed. In the necrotizing fasciitis group (n = 25), 13 (52%) major amputations were undertaken. In the myonecrosis group (n = 11), 6 (54.5%) major amputations were performed. Predictive variables related to limb loss were fasciitis (OR = 20, 95% CI = 3.2-122.1) and myonecrosis (OR = 53.2, 95% CI = 5.1-552.4). Predictive variables of mortality were age >75 years (OR = 10.3, 95% CI = 1.9-53.6) and creatinine values >132.6 micromol/L (OR = 5.8, 95% CI = 1.1-30.2). NSTIs of the foot are an important cause of morbidity and mortality in diabetic patients.When fascia and/or muscle are involved, there are significant risks of major amputation.

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A Retrospective Study of Necrotising Fasciitis

Cited by 4 publications

References 8 publications

Necrotizing fasciitis in adolescents with poorly controlled type 1 diabetes mellitus: report of two cases

Necrotizing fasciitis in adolescents with poorly controlled type 1 diabetes mellitus: report of two cases

Postprocedural Necrotizing Fasciitis: A 10-Year Retrospective Review

Necrotizing Soft-Tissue Infections in the Feet of Patients With Diabetes: Outcome of Surgical Treatment and Factors Associated With Limb Loss and Mortality

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