A retrospective study evaluating the use of Permacol™ surgical implant in incisional and ventral hernia repair

Chand, Bipan; Indeck, Matthew; Needleman, Bradley J.; Finnegan, Matthew; Sickle, Kent R. Van; Ystgaard, Brynjulf; Gossetti, Francesco; Pullan, R. D.; Giordano, Pasquale; McKinley, Aileen

doi:10.1016/j.ijsu.2014.01.025

Cited by 36 publications

(29 citation statements)

References 19 publications

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“…Parietene™ showed the least shrinkage at 30 days after implantation (8(1‐25) per cent). Strattice™ and Omyra ® Mesh showed the least shrinkage 90 days after implantation (15 (13–20) and 15 () per cent respectively). Strattice™ showed the least shrinkage 180 days after implantation (13 (5–17) per cent).…”

Section: Resultsmentioning

confidence: 96%

Characteristics of different mesh types for abdominal wall repair in an experimental model of peritonitis

Kaufmann

Jairam

Mulder

et al. 2017

British Journal of Surgery

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This experimental study suggested that XCM Biologic was superior in terms of incorporation, macroscopic mesh infection, and histological parameters such as collagen deposition and neovascularization. There must be sufficient overlap of mesh during placement, as XCM Biologic showed a high rate of shrinkage. Surgical relevance The use of synthetic mesh to repair a potentially contaminated incisional hernia is not supported unequivocally, and may lead to a higher failure rate. A biological mesh might be considered as an alternative. There are few long-term studies, as these meshes are expensive and rarely used. This study evaluated the use of biological mesh in a contaminated environment, and investigated whether there is an ideal mesh. A new non-cross-linked biological mesh (XCM Biologic ) was evaluated in this experiment. The new non-cross-linked biological mesh XCM Biologic performed best and may be useful in patients with a potentially contaminated incisional hernia.

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Section: Resultsmentioning

confidence: 96%

Characteristics of different mesh types for abdominal wall repair in an experimental model of peritonitis

Kaufmann

Jairam

Mulder

et al. 2017

British Journal of Surgery

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“…This was the European subset analysis from a multicentre retrospective study of patients treated with Permacol TM surgical implant in CAWR [18]. Seven European centres with established practices in CAWR and use of biological mesh participated.…”

Section: Methodsmentioning

confidence: 99%

The use of an acellular porcine dermal collagen implant in the repair of complex abdominal wall defects: a European multicentre retrospective study

et al. 2015

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“…However, this improved outcome has been associated with increased morbidity, with an overall complication rate of 10-77 % [5,15]. Previously, published reports using biological mesh demonstrate improved recurrence and infective complications when compared to non-biological mesh [2,14,23]. Between the biologic graft options, it is widely accepted that the various mesh have differing success and complication profiles [24].…”

Section: Discussionmentioning

confidence: 99%

Ventral hernia repair with lateral component separation and onlay Biodesign graft

et al. 2016

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Background Ventral hernia is common, complicating up to 20 % of laparotomies. Plication of the rectus sheath with lateral component separation (LCS) provides a durable repair with acceptable functional outcomes. Additional support to the anterior abdominal wall may be provided by synthetic or biological mesh. Biological grafts invoke local tissue remodeling and result in strong fibrocollagenous tissue able to support the dynamic stressor of the anterior abdominal wall. Biodesign graft is a new graft derived from porcine smallintestine submucosa. We aim to review the use of Biodesign mesh for repair of ventral hernia with LCS. Methods Patients underwent ventral hernia repair completed with plication of the rectus sheath, LCS, and use of an onlay Biodesign graft. Data was collected retrospectively. Key outcome measures included post-operative complications and recurrence. Results Twelve patients were included for analysis. Mean age was 51.2 years, with 50 % males and a median weight of 87 kg (65-111 kg). Median operative time was 210 min (147 to 278 min) and median length of stay was 4 days. At a mean follow-up of 14.0 months, 8/12 (66 %) developed seroma, 1/12 (8 %) developed abdominal wall abscess, and 1/12 (8 %) suffered flap failure requiring vacuum dressings for closure. No patients were complicated by ventral hernia recurrence. Conclusions Our results describe an early Australian experience of onlay Biodesign graft in the context of rectus sheath plication with LCS. We report acceptable rates of postoperative complications and recurrence. Level of evidence: IV, therapeutic study.

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A retrospective study evaluating the use of Permacol™ surgical implant in incisional and ventral hernia repair

Abstract: NCT01214252 (http://www.clinicaltrials.gov).

Cited by 36 publications

References 19 publications

Characteristics of different mesh types for abdominal wall repair in an experimental model of peritonitis

Characteristics of different mesh types for abdominal wall repair in an experimental model of peritonitis

The use of an acellular porcine dermal collagen implant in the repair of complex abdominal wall defects: a European multicentre retrospective study

Ventral hernia repair with lateral component separation and onlay Biodesign graft

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