A Retrospective Study Comparing 2 Approaches to Catheter-Directed Thrombolysis for Acute Deep Venous Thrombosis

Wang, Haiyang; Qi, Xiaotong; Chen, Yikuan; Sun, Jianming

doi:10.1016/j.avsg.2017.12.026

Cited by 9 publications

(13 citation statements)

References 23 publications

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“…4,7,18 The incidence of complication in the PIVL group was significantly higher than that in NIVL group (41.62% vs. 29.13%), and it could be due to long-dwelling time of sheath, anticoagulation and thrombolysis, large amount of contrast. 9,10 The incidence of complication was consistent with other reports. 10 Chen et al 24 reported that 16 cases of right IVCS mainly occurred in the distal part of the common iliac vein and external iliac vein by internal and external artery bifurcation angles and the right external artery.…”

Section: Discussionsupporting

confidence: 90%

“…9,10 The incidence of complication was consistent with other reports. 10 Chen et al 24 reported that 16 cases of right IVCS mainly occurred in the distal part of the common iliac vein and external iliac vein by internal and external artery bifurcation angles and the right external artery. The right IVCS rate was 8% (24/300) in our study, which pathologies were consistent with the literature, and endovascular therapy was an effective method.…”

Section: Discussionsupporting

confidence: 90%

“…Secondly, the patency of the stent is closely related to the good inflow and outlet. 10,31 Xue et al 4 had found that the valvular incompetence rate was 11.5% approximate, which often results in venous blood stasis, the rate of blood slowed down, and the volume of blood flow reduced. Studies had shown that these changes might lead to intimal hyperplasia and stent thrombosis.…”

Section: Discussionmentioning

confidence: 99%

“…Then catheter-directed thrombolysis (CDT) through a 4 Fr infusion catheter (Unifuse, AgioDynamics, Latham, NY) with multiple holes was performed to cover the thrombosis segments in the affected extremity through anterior tibial vein or popliteal vein in all patients. 9,10,15 After lysis > 90%, 9 if the iliac vein stenosis was >50% by multiple angle venography, and the distal femoral popliteal vein was completely recanalization by angiography, PTA and stent implantation were performed, and the methods of PTA and stent placement were the same as NIVL group. Lastly, all filters were removed through unaffected femoral vein or right internal jugular vein approach.…”

Section: Therapeutic Methodsmentioning

confidence: 99%

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Comparing the efficacy of endovascular treatment for iliac vein compression syndrome with or without acute deep venous thrombosis: A single-center retrospective study

Nie

et al. 2021

Vascular

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Background To compare the efficacy of endovascular treatment for iliac vein compression syndrome (IVCS) with or without acute deep venous thrombosis of lower extremity. Methods This study retrospectively analyzed the clinical data of 300 IVCS patients, who received endovascular treatment between January 2013 and December 2017. According to whether IVCS was complicated by deep venous thrombosis or not, these patients were divided into non-thrombotic iliac vein lesion group (NIVL group, n = 127) and post-thrombotic iliac vein lesion group (PIVL group, n = 173). After endovascular treatment, all patients were followed up to assess the symptoms improvement and to evaluate the patency of iliac vein. Results The technical success rate was 98% (294/300), and percutaneous transluminal angioplasty with stenting was adopted in 294 cases. The incidence of perioperative complications was 36.33% (109/300), but no severe complications occurred. During a mean follow-up of 22.3 months (range 6–30 months), 9(6.82%, 9/132) patients in PIVL group had recurrence of deep venous thrombosis, but nobody had deep venous thrombosis and varicose veins recurrence in NIVL group. The effective rate of endovascular treatment in NIVL group and PIVL group was 96.88% and 90.15% ( P = 0.050), while the cumulative primary patency of iliac vein in NIVL group was significantly higher than that in PIVL group ( P = 0.008). Conclusions The endovascular treatment is an effective, feasible, safe method for treating IVCS. There is no difference in the efficacy of IVCS patients with or without deep venous thrombosis, but the medium and long-term patency of patients with deep venous thrombosis is lower than that in patients without deep venous thrombosis.

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Section: Discussionsupporting

confidence: 90%

Section: Discussionsupporting

confidence: 90%

Section: Discussionmentioning

confidence: 99%

Section: Therapeutic Methodsmentioning

confidence: 99%

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Comparing the efficacy of endovascular treatment for iliac vein compression syndrome with or without acute deep venous thrombosis: A single-center retrospective study

Nie

et al. 2021

Vascular

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“…2 Pulmoner emboli ve DVT'nin nüks riskini azaltmasından dolayı antikoagülasyon tedavi standart olmasına rağmen, sadece antikoagülan kullanan hastaların %20-50'sinde iki yıl içinde posttrombotik sendrom (PTS) gelişmektedir. 3,4 Son yıllarda, trombüsün erken dönemde uzaklaştırılması amacıyla endovasküler yöntemler önemli bir hız kazanmıştır. Kateter aracılı (catheter directed) ve direkt akım trombolitik tedavi [flow directed thrombolytic therapy (FDTT)] uygulamaları, mekanik trombektomi araçları kullanmadan, direkt trombüs içine farmakolojik trombolitik ajan uygulanmasının alt grupları olarak tanımlanmaktadır.…”

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Effificacy of Thrombolytic Therapy Applied Through Foot Veins in Lower Extremity Acute and Subacute Deep Vein Thrombosis

Arslan¹,

Çalık²

2019

Turkiye Klinikleri J Cardiovasc Sci

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Ö ÖZ ZE ET T A Am ma aç ç: : Akut dönemde mortal olabilen ve uzun vadede yaşam kalitesini etkileyen komplikasyonları nedeni ile derin ven trombozu (DVT) önemli bir sağlık sorunudur. DVT'nin tedavisinde kullanılan doku plazminojen aktivatörü (t-PA)'nün pedal venler yolu ile uygulanmasının hem akut hem subakut DVT tedavisindeki etkinliğinin sunulmasıdır. G Ge er re eç ç v ve e Y Yö ön nt te em ml le er r: : Akut ve subakut DVT tanısı alan 83 hastanın pedal venlerine 18 G yeşil branül yerleştirildi. 10 mg t-PA branülden bolus şeklinde uygulandıktan sonra 1 mg/saat dozunda 48-72 saat infüzyon olarak verildi. Kırk sekizinci saat sonunda, 3. 6. ve 12. aylarda doppler ultrasonografi (USG) çekilerek tedavi edilen derin venin akım durumu, reflü süreleri değerlendirildi. Klinik iyileşme için "venous clinical severity score (VCSS)" ve posttrombotik sendrom (PTS) açısından Villalta skorlamaları yapıldı. B Bu ul lg gu ul la ar r: Akut DVT grubunda 44 (26 erkek), subakut DVT grubunda ise 39 (24 erkek) hasta çalışmaya dâhil edildi. Akut grupta 56,4±11,3 mg t-PA 52,3±9,3 saatte, subakut grupta 71,7±14,3 mg t-PA (0,001) 60,3 ±12,1 saatte (0,012) uygulandı. Kırk sekizinci saatte total açılma oranı akut grupta %82 (36 hasta), subakut grupta %43 (19 hasta) idi. On ikinci ayda VCSS ve Villalta skorları akut grupta 3,6±1,8 ve 2,4±1,9 ve subakut grupta 5,8±2,6, 4,3±2,2 olarak hesaplandı (0,008/0,001). Subakut grupta 7 (%18), akut grupta 2 (%4,5) hastada femoropopliteal segmentte asemptomatik DVT nüksü saptandı. Toplamda 14 (%16,8) hastada ise PTS bulguları mevcuttu. S So on nu uç ç: : Anjiyografi ünitesi ve USG gerektirmemesi, kolay uygulanması ve noninvaziv olması nedeni ile bölgesel trombolitik tedavi yönteminin, seçilmiş hastalarda, DVT'nin invaziv olan trombolitik tedavilerine iyi bir alternatif olduğu düşünülmektedir. A An na ah ht ta ar r K Ke el li im me el le er r: : Derin ven trombozu; t-PA; trombolitik tedavi; posttrombotik sendrom K Ke ey yw wo or rd ds s: : Deep vein thrombosis; t-PA; thrombolytic therapy; postthrombotic syndrome Ümit ARSLAN a , Eyüp Serhat ÇALIK a a Kalp Damar Cerrahisi AD, Atatürk Üniversitesi Tıp Fakültesi, Erzurum, TÜRKİYE Re ce i ved:

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The perplexity of catheter-directed thrombolysis for deep venous thrombosis: the approaches play an important role

Qian

Chen

Lou

et al. 2020

J Thromb Thrombolysis

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A Retrospective Study Comparing 2 Approaches to Catheter-Directed Thrombolysis for Acute Deep Venous Thrombosis

Cited by 9 publications

References 23 publications

Comparing the efficacy of endovascular treatment for iliac vein compression syndrome with or without acute deep venous thrombosis: A single-center retrospective study

Comparing the efficacy of endovascular treatment for iliac vein compression syndrome with or without acute deep venous thrombosis: A single-center retrospective study

Effificacy of Thrombolytic Therapy Applied Through Foot Veins in Lower Extremity Acute and Subacute Deep Vein Thrombosis

The perplexity of catheter-directed thrombolysis for deep venous thrombosis: the approaches play an important role

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