A retrospective study analysing mortality and outcomes in the paediatric burns intensive care unit at the Chris Hani Baragwanath Academic Hospital, Johannesburg

Mashavave, N Z; Withers, A; Doedens, L.; Jugmohan, Ben; Loveland, Jerome

doi:10.7196/sajch.2020.v14i4.01724

Cited by 4 publications

(12 citation statements)

References 18 publications

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“…Multiple studies found that perinatal risk factors were most prominent, with approximately half to two‐thirds of several cohorts reporting perinatal events (Table S3). In particular, neonatal HIE, 11,32,37–42,46,53,54,59–63 kernicterus, 11,32,33,37–42,44,46,53,54,60–63 and infections 11,22,32,37–41,46,52,53,60–65 were important risk factors for CP in Africa. Cohort studies found that the proportion of children with CP at follow‐up was 15.5% among those with HIE in South Africa ( p < 0.001), 59 16.5% among those with kernicterus in Nigeria, 44 and 7.7% among those with enteroviral meningitis in Tunisia 64 …”

Section: Resultsmentioning

confidence: 99%

“…Although possible aetiologies for CP in African children ranged from antenatal through peripartum to postnatal factors, 11,19,22,32,33,37–63 the proportion of children with no identifiable risk factors was as high as 26% even in hospital‐based populations (Table S3). 11 …”

Section: Resultsmentioning

confidence: 99%

“…This association was supported by six studies on neuroimaging, which also reported that up to 76.1% of children with abnormal imaging had acquired lesions consistent with perinatal insults, such as HIE (Table 4). 33,38,50,66–68 …”

Section: Resultsmentioning

confidence: 99%

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Cerebral palsy in African paediatric populations: A scoping review

Murugasen,

Springer,

Olusanya

et al. 2024

Develop Med Child Neuro

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AimTo review the epidemiology and outcomes of African children with cerebral palsy (CP) over a 21‐year period.MethodThe PubMed, Scopus, and Web of Science online databases were searched for original research on African children with CP aged 18 years and younger published from 2000 to 2021.ResultsA total of 1811 articles underwent review against explicit criteria; 93 articles were selected for inclusion in the scoping review. The reported prevalence of CP ranged from 0.8 to 10 per 1000 children. Almost half had perinatal risk factors, but up to 26% had no identifiable risk factor. At least one‐third of children with CP had one or more comorbidities, most commonly epilepsy, intellectual disability, and malnutrition. African children with CP demonstrated excess premature mortality approximately 25 times that of the general population, predominantly from infections. Hospital‐based and younger populations had larger proportions of children with severe impairments. African children with CP had inadequate access to care and education, yet showed functional improvements compared to controls for all evaluated interventions.InterpretationThe prevalence of CP in Africa remains uncertain. African children with CP have different risk profiles, greater premature mortality, and more severe functional impairments and comorbidities compared to the Global North. Several barriers prevent access to optimal care. Larger African studies on validated and effective interventions are needed.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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Cerebral palsy in African paediatric populations: A scoping review

Murugasen,

Springer,

Olusanya

et al. 2024

Develop Med Child Neuro

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“…The latest data reported by the Perinatal Problem Identification Programme in the Saving Babies Report show that intrapartum hypoxia makes up 24.3% of all neonatal deaths where the birthweight was >500 g. [5] While accurate figures for intrapartum-related causes of CP in South Africa (SA) are not known, it is likely to follow that, with this large number of deaths owing to intrapartum hypoxia, the number of infants surviving such an insult with neurological damage will probably be substantially higher than in high-income countries. This view is supported by a retrospective study by Mahlaba et al [6] where 144 cases of CP were reviewed, of which 88 had neuroimaging reports and 42% of these showed evidence of hypoxic-ischaemic injury.…”

Section: Supplementmentioning

confidence: 88%

Cerebral Palsy and Criteria Implicating Intrapartum Hypoxia in Neonatal Encephalopathy – An Obstetric Perspective for the South African Setting

et al. 2021

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“…Additionally, a retrospective study conducted in Sudan, focusing on hospital-based data, revealed burns as the fourth most common traumatic injury type, with a mortality rate of 5.9% (Bakhiet, 2023). In South Africa, a retrospective cohort study found an overall mortality rate of 4.4% for pediatric burns, with a higher mortality rate among transferred patients compared to directly admitted cases (Mashavave, 2020). Another study in Nepal reported a prevalence of acute pediatric burns in a hospital setting to be 29.71%, with a mortality rate of 10.89% (Nakarmi, 2020).…”

Section: Discussionmentioning

confidence: 99%

Clinical Assesment of Pediatric Burns: A Retrospective Study

GÜN SOYTÜRK,

KILIÇ,

ORUÇ

2023

Sabuncuoglu Serefeddin Health Sciences

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Burn injuries represent a significant aspect of pediatric traumas, particularly prevalent during early childhood, involving a critical patient population characterized by elevated mortality and morbidity rates. This study explores burn incidents in children aged 0-6 years admitted to the Burn Unit of a tertiary hospital between January 1, 2016, and June 20, 2023, within the context of the existing literature. Additionally, it conducts an analysis of burn etiology, distribution, severity, and treatment interventions, categorizing a sample of 241 pediatric burn patients, predominantly within the 0-18 month age range. Children are categorized into three groups based on Sigmund Freud's "psychosexual development stages": 0-18 months, 18-36 months, and 36-72 months. Statistical analyses were performed using SPSS 25, with a predetermined significance level of 0.05. Burns commonly present as scalds, flames, and chemical burns, primarily falling within the 11-20% range and predominantly involving second-degree burns. Treatment approaches include a combination of dressing and medical treatment in 68% of cases, debridement under general anesthesia in 16.2%, and grafting in 15.8%. The infection rate is 10.8%, with Pseudomonas Aeruginosa emerging as the predominant pathogen, and the mortality rate reported at 0.8%. The average hospitalization duration is 9 days. Highlighting the paramount importance of meticulous planning in managing burns in children under 6 years old and emphasizing the influence of parental factors, the study advocates for educating parents on safety measures as a crucial step in mitigating burn incidence. Stressing the pivotal role of epidemiological investigations in comprehending and preventing the root causes of burns, the research suggests that more extensive age-range studies and multicenter approaches could provide more robust epidemiological insights for the effective management of burn cases.

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A retrospective study analysing mortality and outcomes in the paediatric burns intensive care unit at the Chris Hani Baragwanath Academic Hospital, Johannesburg

Cited by 4 publications

References 18 publications

Cerebral palsy in African paediatric populations: A scoping review

Cerebral palsy in African paediatric populations: A scoping review

Cerebral Palsy and Criteria Implicating Intrapartum Hypoxia in Neonatal Encephalopathy – An Obstetric Perspective for the South African Setting

Clinical Assesment of Pediatric Burns: A Retrospective Study

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