A retrospective review of 228 episodes of infective endocarditis where rheumatic valvular disease is still common

Çetinkaya, Yeşim; Akova, Murat; Akalın, Halis; Aşçıoğlu, Sibel; Hayran, M.; Uzuns, Ö; Aksöyek, Serdar; Tokgozoglu, L.; Oto, Ali̇; Kes, Sırrı; Paşaoğlu, İlhan; Ünal, Serhat

doi:10.1016/s0924-8579(01)00344-2

Cited by 29 publications

(19 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…As was true in other series from developing countries, 9,10,24 the most characteristic finding in our study was the high rate of negative blood cultures (31.4%); the negative rate in industrialized countries, by contrast, has been reported at 5% to 15%. 25,8 The common causative factors involved in the high frequency of IE negative blood cultures (in the presence of infective endocarditis) include previous antibiotic therapy, the lack of optimal conventional culture techniques, and the failure of systematic investigation for rare and fastidious microorganisms.…”

Section: Discussionsupporting

confidence: 88%

“…[8][9][10] In Western countries, the average age of such patients has shifted from 55 to 60 years in recent decades. This shift has been attributed to the dramatic decrease in the incidence of acute rheumatic disease and to increased lifespans that have given rise to more degenerative valvular lesions, to the placement of prosthetic valves, and to increased exposure to nosocomial bacteremia.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Changing Profile of Infective Endocarditis: A Clinicopathologic Study of 220 Patients in a Single Medical Center from 1998 through 2009

Li¹,

Wang²,

Wang³

et al. 2014

Texas Heart Institute Journal

View full text Add to dashboard Cite

The epidemiologic profile of infective endocarditis has changed substantially over the past few years, especially in industrialized countries. Our study evaluates the clinical and pathologic characteristics of infective endocarditis patients treated by cardiac surgery in China during a 12-year period. We retrospectively evaluated 220 surgically treated infective endocarditis patients and analyzed their changes from the beginning of 1998 through 2009. The mean age of the patients increased from 36.9 to 42.7 years during those 12 years (P=0.036). The chief predisposing disease was congenital heart disease (32.8%), rather than rheumatic heart disease (13.2%); this rate did not change significantly during the 12 years. The prevalent congenital lesion was bicuspid aortic valve, the rate of which (55.6%) increased significantly over the 3 time intervals studied (P=0.016). The frequency of infective endocarditis after non-dental surgical and nonsurgical intervention was significantly greater (23.3%) during 1998 through 2001, compared with the 2 intervals that followed (9%; P=0.019). Streptococcus viridans was the most frequent causative agent overall (25.6%). Forty-seven of the 220 patients (21.4%) carried the clinical diagnosis of some other form of heart disease before surgery, but at surgery they were found to have infective endocarditis as the fundamental disease process. Of 47 patients, 33 (70.2%) had either very small or no vegetations but had focal necrosis and inflammation of valve tissue that supported the diagnosis of infective endocarditis.

show abstract

Section: Discussionsupporting

confidence: 88%

Section: Discussionmentioning

confidence: 99%

Changing Profile of Infective Endocarditis: A Clinicopathologic Study of 220 Patients in a Single Medical Center from 1998 through 2009

Li¹,

Wang²,

Wang³

et al. 2014

Texas Heart Institute Journal

View full text Add to dashboard Cite

show abstract

“…This interest in endocarditis persisted: An additional 8 studies [37][38][39][40][41][42][43][44][45][46][47][48] from Asia were found during the preparation of the present report (Table 3). The recent studies from India, Turkey, and Lebanon all found that rheumatic heart disease was the most common underlying factor in endocarditis (range 33% to 66%), 41,44,45,47 whereas studies from Hong Kong and Thailand found rheumatic heart disease in 18% and 12% of cases, respectively, 42,46 and a study from Singapore found rheumatic heart disease in only 4% of endocarditis cases.…”

Section: Endocarditismentioning

confidence: 79%

Rheumatic Heart Disease in Asia

Carapetis

2008

Circulation

View full text Add to dashboard Cite

“…26 Overall, this range of underlying RHD in IE represents a decline from the 45-80% reported in earlier (pre-2000) LMIC studies. 10,11,13,27,28 Compared to HICs however, these findings are remarkable in that RHD is identified in only 3% of IE cases. 1 This is likely because the prevalence of RHD is disproportionately high in LMICs, 29,30 which bear 79% of the global RHD burden.…”

Section: Underlying Cardiac Conditionsmentioning

confidence: 96%

Infective Endocarditis in Low- and Middle-Income Countries

et al. 2017

View full text Add to dashboard Cite

Key Points Staphylococcus is an increasingly important cause of IE in LMICs, and is the leading cause of IE in UMICs  RHD remains the major underlying cardiac pathology of IE in LMICs, identified in almost half of reported cases  The rate of microorganism non-identification is high, reaching up to 60% of IE cases in LMICs, and hampering diagnosis and treatment  Rates of access to surgery in UMICs for complicated IE are as high as in HICs, but remain dismal in lower-middle income countries SynopsisInfective endocarditis (IE) is a rare, life-threatening disease with a mortality rate of upto 25% and significant debilitating morbidities. Although much has been reported on contemporary IE in high income countries, conclusions on the state of IE in low and middle income countries (LMICs) are based on studies conducted before the year 2000. Furthermore, unique challenges in the diagnosis and management of IE persist in LMICs. This article is a review of IE studies conducted in LMICs documenting clinical experiences from the year 2000 to present. We present the causes of IE, management of patients with IE and the prevailing challenges in diagnosis and treatment of IE in LMICs.

show abstract

A retrospective review of 228 episodes of infective endocarditis where rheumatic valvular disease is still common

Cited by 29 publications

References 26 publications

Changing Profile of Infective Endocarditis: A Clinicopathologic Study of 220 Patients in a Single Medical Center from 1998 through 2009

Changing Profile of Infective Endocarditis: A Clinicopathologic Study of 220 Patients in a Single Medical Center from 1998 through 2009

Rheumatic Heart Disease in Asia

Infective Endocarditis in Low- and Middle-Income Countries

Contact Info

Product

Resources

About