A retrospective observational study of Chlorine Dioxide effectiveness to covid19-like symptoms prophylaxis in relatives living with COVID19 patients

Abstract

To date, there is no effective prophylactic agent to prevent COVID-19. However, the development of symptoms similar to covid19 could be prevented with an aqueous solution of chlorine dioxide (ClO2). This retrospective study evaluated the effectiveness of an aqueous solution of ClO2 (CDS) as a prophylactic agent in 1,163 family members living with positive/suspected COVID19 patients. Prophylactic treatment consisted of 0.0003% chlorine dioxide solution (CDS) orally for at least fourteen days. Family members in whom no reports of the development of covid19-like symptoms were found in the medical history were considered successful cases. The efficacy of CDS in preventing covid19-like symptoms was 90.4% (1,051 of 1,163 relatives did not report any symptoms). The comorbidities, sex and severity of the illness of the sick patient did not contribute to the development of symptoms similar to covid19 (P = 0.092, P = 0.351 and P = 0.574, respectively). However, older relatives were more likely to develop covid19-like symptoms (ORa = 4.22, P = 0.002). There was no evidence of alterations in blood parameters or in the QTc interval in relatives who consumed CDS. The recent findings regarding Chlorine Dioxide justify designing clinical trials to assess its efficacy for preventing SARS-CoV-2 infection.

Can nasal irrigation with chlorine dioxide be considered as a potential alternative therapy for respiratory infectious diseases? The example of COVID-19

“…2). Aparicio-Alonso et al reported that oral administration of ClO 2 at 3 ppm in a dose of 0.3 mg/kg/ day was safe (9). Assuming the body weight of an adult is 50 kg, oral consumption of 15 mg/day ClO 2 is safe.…”

“…). Aparicio-Alonso et al orally administered ClO 2 at 3 ppm as a prophylactic agent to family members living with COVID-19 patients in Mexico(9). They found that ClO 2 was effective at preventing COVID-19, and no adverse events were reported.…”

Focusing on development of novel sampling approaches and alternative therapies for COVID-19: Are they still useful in an era after the pandemic?

“…They contend that such nasal irrigation may "wash out the nasal cavity", helping to reduce the viral load in the upper respiratory tract and thereby ameliorating COVID-19-related symptoms. Studies in Mexico even orally administered chlorine dioxide (ClO 2 ) in a low dose to prevent/treat COVID-19-related symptoms in relatives living with COVID-19 patients (7,8). iii) Alleviation of symptoms using natural products: This scenario includes a number of natural products such as Indonesian herbal compounds (9), Iran herbal medicine (10), propolis and honey (11), Indian herbs (12), essential oils (13), and traditional Chinese medicine (TCM) (14)(15)(16).…”