A Retrospective Analysis of Prevalence of Uropathogens and Antibiotic Sensitivity Pattern in Patients of Urinary Tract Infection in a Tertiary Care Teaching Hospital

Patil, Trilok; Jain, Manish

doi:10.21276/iabcr.2016.2.3.14

Cited by 4 publications

(5 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These findings are in conformity with the reports by other researchers. [ 9 11 ] According to Alzohairy and Khadri[ 9 ] and Patil and Jain,[ 1 ] Pseudomonas species was the third most common uropathogen, but this is contrary to our study, which showed that E. faecalis is the third one.…”

Section: Discussioncontrasting

confidence: 92%

“…Generally antibiotics are prescribed empirically for urinary tract infection (UTI) before the final urine culture laboratory results are available. [ 1 ] Choice of empirical antibiotic prescription depends on the knowledge of bacterial organisms that are prevalent locally and antibiotic sensitivities, rather than on universal guidelines. [ 2 3 4 ] In recent years, bacterial resistance to various antibiotics has raised dramatically, forcing physicians with few therapeutic choices.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Bacteria causing urinary tract infections and its antibiotic susceptibility pattern at tertiary hospital in Al-Baha region, Saudi Arabia: A retrospective study

2020

View full text Add to dashboard Cite

A BSTRACT Context: Clinicians face one of the most common bacterial infections in developing countries that is urinary tract infection (UTI). Current knowledge on antimicrobial susceptibility pattern is essential for selecting appropriate therapy. Aims: In this study, we investigated the various bacteria causing UTI and determined the sensitivity and resistance of antibiotics pattern against most prevalent uropathogens isolated from patients at tertiary hospital, Al-Baha, Saudi Arabia. Settings and Design: This was a retrospective study of urine culture conducted in King Fahad Hospital at Al-Baha in Saudi Arabia. Materials and Methods: Laboratory reports and patient medical files of both inpatient and outpatient were collected between June 2017 and May 2018, targeting both male and female of age above 18 years of age, who had been treated for UTI. Results: A total of 349 patients’ urine report was studied to identify the uropathogens. Escherichia coli was the main etiologic agent in community and hospital-acquired infections. The majority of the bacteria was isolated from female (60%), whereas the remaining (40%) was from male. The most common isolates were E. coli, Klebsiella pneumoniae, Enterococcus faecalis, E. coli Extended spectrum beta-lactamases , Pseudomonas , and K. pneumoniae ESBL (these represented 37.82%, 19.20%, 10.89%, 10.32%, 6.59%, and 3.72%, of isolate, respectively). UTI due to E. coli was at a higher rate during summer than during winter. This study showed that ciprofloxacin (20.29%) and cefuroxime (16.14%) are most prescribed medications, followed by ceftriaxone (12.96%) and then tazocin (8.80%). Imipenem, meropenem, amikacin, vancomycin, tigecycline, linezolid, and colistin were highly sensitive for most types of bacteria, but gram-negative bacteria were highly resistant to ampicillin. Gram-positive bacteria showed highly resistance to cefoxitin. Conclusion: The microbial culture and sensitivity of the isolates from urine samples should be carried out as a routine before starting the antimicrobial therapy. Current knowledge of the antibiotic sensitivity/resistance patterns of uropathogens at a particular geographical region is a guiding factor for choosing an appropriate empirical antimicrobial treatment rather than following universal guidelines.

show abstract

Section: Discussioncontrasting

confidence: 92%

Section: Introductionmentioning

confidence: 99%

Bacteria causing urinary tract infections and its antibiotic susceptibility pattern at tertiary hospital in Al-Baha region, Saudi Arabia: A retrospective study

2020

View full text Add to dashboard Cite

show abstract

“…The magnitude of CAUTI was higher in female (63.63%) than male patients (36.36%), which is in agreement with other studies such as Patil and Patil 21 and Nadeem R et al 22 This female predominance is due to short urethra, its proximity to the anus, and dilatation of the urethra, which makes it easier for bacteria to spread, leading to infection. Hence, in females, catheterization should be done when absolutely indicated.…”

Section: Discussionsupporting

confidence: 90%

An Observational Study from Northern India to Evaluate Catheter-associated Urinary Tract Infection in Medical Intensive Care Unit at a Tertiary Care Centre

Sharma,

Parihar,

Kinimi

et al. 2023

Indian Journal of Critical Care Medicine

View full text Add to dashboard Cite

A bstract Background Healthcare-associated infections are the leading cause of morbidity and mortality in hospitalized patients. Catheter-associated urinary tract infection (CAUTI) is a leading infection in ICU settings. This study aims to evaluate the patient and catheter-related factors contributing to the urinary tract infection as well as implementing the preventive measures ultimately curbing down the burden of healthcare-associated infections. Material and methods This is a hospital-based observational study conducted in Department of Microbiology, from October 2020 to September 2021. A total of 150 patients admitted to Medical Intensive Care Unit (MICU) with the indwelling urinary catheter were included. Urine samples were collected with proper aseptic precautions and processed within 2 hours of collection. Identification and antimicrobial susceptibility testing of the isolated pathogens was done as per CLSI guidelines 2019. Results In this study, the CAUTI rate was 9.4 per 1000 urinary catheter days, while the overall magnitude was 14.67%. It was predominantly reported in 51–70-years age group (34%), and females (63.63%) outnumbered males (36.36%), with Escherichia coli being the commonest pathogen. The highest incidence was reported in the 3rd week of catheterization with diabetes being a predominant risk factor (17.24%). Conclusion This study provides baseline data on CAUTI rate, pathogens isolated, and risk factors at our institute. The overall goal is to identify, educate, and implement best-practice measures for prevention and curbing down the incidence rates of catheter-associated urinary tract infections. How to cite this article Parihar S, Sharma R, Kinimi SV, Choudhary S. An Observational Study from Northern India to Evaluate Catheter-associated Urinary Tract Infection in Medical Intensive Care Unit at a Tertiary Care Center. Indian J Crit Care Med 2023;27(9):642–646.

show abstract

“…The most prevalent bacteria was E. coli (26.6%) which is lower than report from Arbaminch, Ethiopia (40.5%) (11), Jimma, Ethiopia (42.0%) (27), Yemen (46.3%) (28), and most parts of India (31%-38%) (15,16,18,19,24). Studies conducted in Yemen (18.5%) (28), Chhattisgarh, India(17%) (24), Maharashtra, India (16.4%) (16), and Chhattisgarh, India (24), reported low proportion of Klebsiella species unlike our study (22.2%) which is the second most prevalent bacteria.…”

Section: Ciprofloxacinmentioning

confidence: 66%

Magnitude and Factors Associated with Catheter Associated Urinary Tract Infection, and Antimicrobial Susceptibility Profile at Hawassa, Sidama Regional State, Ethiopia: A prospective Cross-sectional Study

Kefeni,

Anticho,

Tesema

et al. 2024

EMJ

View full text Add to dashboard Cite

Introduction: The use of urinary catheter benefit patients who are unable to urinate for various medical reasons. Despite its use, a urinary catheter during its application may introduce bacteria to the urinary tract and result in Urinary tract infection (UTI). Even though the burden of catheter-associated UTI is expected to be high in resource-limited countries, there is limited data. The aim of this study was to determine the magnitude of culture- confirmed catheter-associated urinary tract infection (CAUTI), associated factors, and antimicrobial susceptibility profiles of bacteria. Methods: This prospective cross-sectional study was conducted at Hawassa University Comprehensive Specialized Hospital (HUCSH), Sidama region, from May-August 2022. One hundred forty-nine catheterized patients at HUCSH were included. Socio-demographic, clinical, and laboratory data were collected using structured questionnaire. Urine specimens were cultured on blood and MacConkey agar. Culture-confirmed catheter-associated urinary tract infection was established if >1 X 105 colonies of bacteria per milliliters of urine was detected. The disc diffusion method was used for antimicrobial susceptibility testing. For data analysis, SPSS version 26 was used. Factors associated with culture-confirmed CAUTI were assessed using binary logistic regression. Results: The magnitude of culture confirmed CAUTI was 30.2% (n=45; 95% CI=22.8−37.6). The most common bacterial isolates were Escherichia coli (n=12; 26.7%), followed by Klebsiella species (n=10; 22.2%), and Staphylococcus aureus (n=6; 13.3%). Duration of catheterization (AOR=9.6, 95% CI=3.8−24.2) and comorbidities (AOR=4.1, 95% CI=1.7−9.8) were significantly associated with culture-confirmed CAUTI. Most Gram- negative bacteria were resistant to commonly prescribed antimicrobial agents. Conclusions: The magnitude of culture-confirmed CAUTI at HUCSH was high. E. coli was the leading bacteria and most of them were resistant to various types of antimicrobial agents. Duration of catheterization and comorbidities were significantly associated with culture- confirmed CAUTI.

show abstract

A Retrospective Analysis of Prevalence of Uropathogens and Antibiotic Sensitivity Pattern in Patients of Urinary Tract Infection in a Tertiary Care Teaching Hospital

Cited by 4 publications

References 0 publications

Bacteria causing urinary tract infections and its antibiotic susceptibility pattern at tertiary hospital in Al-Baha region, Saudi Arabia: A retrospective study

Bacteria causing urinary tract infections and its antibiotic susceptibility pattern at tertiary hospital in Al-Baha region, Saudi Arabia: A retrospective study

An Observational Study from Northern India to Evaluate Catheter-associated Urinary Tract Infection in Medical Intensive Care Unit at a Tertiary Care Centre

Magnitude and Factors Associated with Catheter Associated Urinary Tract Infection, and Antimicrobial Susceptibility Profile at Hawassa, Sidama Regional State, Ethiopia: A prospective Cross-sectional Study

Contact Info

Product

Resources

About