A retrospective analysis of ovarian endometriosis during pregnancy

Endometriosis in para-aortic lymph nodes during pregnancy: case report and review of literature

“…Given that endometriosis-related symptoms tend to occur after menarche and before menopause, and that multiparity decreases risk, endometriosis is expected to regress with pregnancy (1). However, a recent retrospective analysis found that to be the case in only 52% of endometriomas, and 20% were found to increase in size (14). Our patient's clinicopathologic presentation supports the idea that endometriosis is capable of more aggressive presentation, such as lymphatic spread, even during pregnancy.…”

Severe spontaneous hemoperitoneum in pregnancy may be linked to in vitro fertilization in patients with endometriosis: a systematic review

“…Among 24 ovarian endometriomas observed during pregnancy, the size of the cyst increased significantly during the second trimester in the two IVF cases. One of these subsequently ruptured, and one developed an abscess (15). Nevertheless, there remains a lack of consensus about the optimal management of endometrioma in women undergoing IVF (73).…”

“…Two maternal deaths have recently been reported due to a delay in the diagnosis of SHiP (13,14). Ueda et al (15) reported abscess formation and rupture in 2 of 25 cases with endometriomas who underwent IVF. On the other hand, assisted reproductive technology was not linked to adverse pregnancy outcome in a recent study involving 539 dichorionic-diamniotic twins (16).…”

Pregnancy affects morphology of induced endometriotic lesions in a mouse model through alteration of proliferation and angiogenesis

“…In the baboon model, D'Hooghe et al found no reduction in endometriotic lesion size during pregnancy but only by laparosopic analysis [25]. In women, Ueda et al showed a significant reduction in endometrioma size, assessed by ultrasound scan, during pregnancy [26]. A few observations of bowel [27,28] and umbilical endometriosis [29] harvested during pregnancy have been reported and confirm a decidualized stroma and polymorphic nuclei.…”