A Retrospective Analysis of Efficacy of Non-Surgical Treatment for Diabetic Chronic Osteomyelitis

Abstract

AIM & OBJECTIVE:The primary aim was to evaluate the efficacy and response rate of non-surgical treatment in diabetic Chronic Osteomyelitis. RESEARCH DESIGN & METHODS: All patients with Diabetic Chronic Osteomyelitis seen in outpatient & inpatient Orthopedic and Surgical department of tertiary care medical college hospital from January 2012 to January 2013 were evaluated. Response rate to non-surgical treatment was measured in terms of absence of infection at site of initial injury or contiguous site for a follow up period of 6 months. Patients were evaluated in terms of demographic, clinical and therapeutic variables, which included probe testing, swab culture and sensitivity and empiric antibiotic sensitivity testing. RESULTS: 100 consecutive patients aged between 30years to 70 years (mean age 60.2±4 yrs (mean ± SD)) with co-existing diabetes since last 15-20 years were included in study. CONCLUSION: Pus culture based and bone culture based antibiotic therapy was proved as primary variable leading to remission with avoidance to surgical debridement and curettage or amputation. Secondly Staphylococcus aureus followed by Pseudomonas aeruginosa along with MRSA and ESBL were major source of infection.