A retrospective analysis of 232 newly diagnosed pulmonary tuberculosis cases

Etiz, Pınar; Altunsu, Ali Tanju

doi:10.5222/tmcd.2018.117

Cited by 1 publication

(1 citation statement)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Tuberculosis (TB) remains an important health problem worldwide and the subject of ongoing research. The TB incidence rate in Turkey in 2013 was 20/100.000 with a mortality rate of 0.42 per 100.000 (1). Ethambutol is an important first-line drug used in the treatment of TB; however, the drug has an important potential side effect on the eye: the incidence of ethambutol-induced optic neuropathy has been reported to be 1-5% (2).…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the long-term effect of ethambutol usage on the retinal nerve fiber layer using spectral domain optical coherence tomography

Varan¹

2020

Beyoglu Eye J

View full text Add to dashboard Cite

The aim of this study was to use spectral-domain optical coherence tomography (SD-OCT) to evaluate the long-term effect of ethambutol on the optic nerve fiber layer. Methods: Twenty eyes of 10 patients who had been treated with ethambutol for tuberculosis were retrospectively evaluated. Retinal nerve fiber layer (RNFL) analyses performed initially and about 2 years after the end of treatment were included in the study. Data of visual acuity, fundus examination, other diseases, and drug use history of all of the participants were evaluated. Color vision was tested with the Ishihara Color Test. Superior, inferior, nasal, and temporal quadrant RNFL parameters were evaluated using SD-OCT. Results: The mean age of the 10 patients was 38.77±14.86 years. There were 6 males and 4 females in the group. The mean length of follow-up was 4.44±1.94 months (range: 2-8 months). The mean RNFL result of the analysis performed 2 years after discontinuation of ethambutol treatment was superior RNFL: 122.45±18.64 µ, inferior RNFL: 131.40±13.31 µ, temporal RNFL: 71.60±8.53 µ, and nasal RNFL: 81.70±9.73 µ. There was significant thinning in the temporal quadrant (p<0.05). Conclusion:Long-term use of ethambutol caused thinning in the RNFL. SD-OCT is useful in the follow-up of these patients.

show abstract

Section: Introductionmentioning

confidence: 99%

Evaluation of the long-term effect of ethambutol usage on the retinal nerve fiber layer using spectral domain optical coherence tomography

Varan¹

2020

Beyoglu Eye J

View full text Add to dashboard Cite

show abstract

A retrospective analysis of 232 newly diagnosed pulmonary tuberculosis cases

Cited by 1 publication

References 5 publications

Evaluation of the long-term effect of ethambutol usage on the retinal nerve fiber layer using spectral domain optical coherence tomography

Evaluation of the long-term effect of ethambutol usage on the retinal nerve fiber layer using spectral domain optical coherence tomography

Contact Info

Product

Resources

About