A restraint system for the psychophysiological study of dogs

Anderson, David E.; Daley, L. A.; Findley, Jack D.; Brady, Joseph V.

doi:10.3758/bf03209302

Cited by 26 publications

(5 citation statements)

References 2 publications

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“…The dogs were placed in a restraining harness that permitted them to lie confortably (10), and were allowed to adjust to the surroundings; their movements were monitored by closed circuit television.…”

Section: Methodsmentioning

confidence: 99%

Stability of the heart rate power spectrum over time in the conscious dog

et al. 1989

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The purpose of this experiment was to test the stability of the heart rate (HR) power spectrum over time in conscious dogs. HR was recorded for 1 h for each of six animals on 2 days. A Fast Fourier transform was used to derive the HR power spectrum for the 12 contiguous 5-min epochs comprising the 1-h recordings. Changes in frequency and amplitude of the various spectral peaks were quantitatively examined. We confirm the presence of two major concentrations of power centered around 0.02 (low frequency peak) and 0.32 Hz (high frequency peak). However, we observed variations in these spectral peaks, especially their amplitudes, both within each hour and from day 1 to day 2. The amplitudes of these two spectral peaks tended to vary reciprocally. HR power spectra based on 5 min of recorded data were also derived from an additional eight animals in both the lying and standing positions; the power spectra from these short recordings were sufficiently sensitive to detect redistributions in power due to changes in posture in all eight dogs. We conclude that: 1) data should be recorded for relatively long periods (e.g., 1 h) to characterize the HR power spectrum; 2) some variability in frequency and amplitude will persist across spectra even when based on longer data bases; 3) care should be taken to ensure that the subject's behavioral state is stable within the recording period; 4) shorter (e.g., 5 min) data bases are not suitable except for detecting relatively robust changes in the HR power spectrum.

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Section: Methodsmentioning

confidence: 99%

Stability of the heart rate power spectrum over time in the conscious dog

et al. 1989

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“…Eight mongrel dogs (five male, three female), weighing 14-30 kg, were trained to sit quietly within an isolation chamber-restraint system designed by Anderson et al (1970). The subjects were placed in the light and sound attenuated chamber for 2 hours daily (range, 5-16 days).…”

Section: Adaptationmentioning

confidence: 99%

Mechanisms mediating the coronary vascular response to behavioral stress in the dog.

Billman¹,

Randall²

1981

Circulation Research

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Left circumflex coronary blood flow (CBF) was measured in eight mongrel dogs with 8 MHz continuous wave Doppler flow transducers during classical aversive conditioning. The cardiovas-cular condition response consisted of significant (P < 0.01) increases in: (1) mean aortic pressure (16.1%), (2) d(left ventricular pressure)/dt (64.2%), and (3) heart rate (63.2%). The coronary vascular response to behavioral stress consisted of an initial late diastolic decrease in CBF (12.5%) between 5 and 10 seconds after conditional stimulus onset, followed by a significant increase in CBF (96.8%). Concurrently, late diastolic coronary vascular resistance (CVR) first significantly increased (21.9%), then significantly decreased (39.8%). The increase in CVR was attenuated by cardiac pacing and converted into a significant decrease after a-receptor blockade. The decrease in CVR was reduced either by cardiac pacing or cardioselective ^-receptor blockade and eliminated by the combination of a-and /J-receptor blockade. Thus, these data indicate that the coronary vascular response to stress consisted of two components: an initial o-adrenergic coronary vasoconstriction, followed by a more complex vasodilation which was probably mediated by metabolites released secondarily to increases in heart rate and inotropic state. Circ Res 48: 214-223, 1981 WHEN an organism faces an unpleasant or life-threatening situation, a variety of circulatory adjustments must be made to either fight or flee the danger. Important adaptations must occur at the heart, particularly the coronary vessels, so that the increased nutritive demands of the organism can be matched immediately without impairing cardiac function. Thus the survival benefits of a rapidly responding coronary vascular system cannot be un-derstated. Yet, in spite of the importance of this response system, very little information is available on the mechanism(s) mediating the coronary vas-cular response to emotional stress. Excitatory stimuli have been demonstrated to produce intense activation of the sympathetic nervous system (Cohen and Obrist, 1975). Sympathetic stimulation of the myocardium indirectly affects coronary vessel diameter by increases in the chron-otropic and inotropic state of the heart. These, in turn, increase myocardial oxygen consumption and thereby increase coronary blood flow (CBF), presumably through the release of vasodilatory me-tabolites (Rubio and Berne, 1975). The task of characterizing the direct sympathetic control of coronary vascular diameter is complicated since coronary smooth muscle contains both a-and yS-adre

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“…Five adult male dogs (two beagles and three mongrels), each weighing approximately 25 lb (11 kg), served as subjects. The animals were confined in a specially designed flexible restraint harness and experimental isolation chamber (7) which provided freedom of movement in a number of standi'ng, sitting, or lying positions. The harness served the purpose of affording protection for indwelling arterial catheters, associated strain-gage transducers, and shock electrodes.…”

mentioning

confidence: 99%