A Report of Rabbit Syndrome Who Benefited from Sigma 1 Agonist Fluvoxamine

Abstract

Rabbit Syndrome is an uncommon side effect of antipsychotic treatment. Although it is usually associated with typical antipsychotics, it can also be related to atypical antipsychotics. Anticholinergics are the most accepted treatment approach in treating Rabbit Syndrome. Fluvoxamine is a member of selective serotonin reuptake inhibitors and it is a potent agonist of sigma 1 receptors. In this article, we report a Rabbit Syndrome case who has benefited from fluvoxamine, in terms of both depressive disorder and Rabbit Syndrome; and present the data on the effects of sigma 1 agonist fluvoxamine on numerous movement disorders.

Fluoxetine-Induced “Rabbit Syndrome” in a Child With Juvenile Obsessive-Compulsive Disorder

“…6 A recent report from Turkey has described a case of rabbit syndrome alleviated by the selective serotonin reuptake inhibitor, fluvoxamine with a putative s-1 agonistic action. 7 To the best of our knowledge, this case is one of the earliest to report "rabbit syndrome" in CAP population related to selective serotonin reuptake inhibitor use. Although these reports remain scattered, prescribes should be cognizant of these unusual side effects.…”

“…6 A recent report from Turkey has described a case of rabbit syndrome alleviated by the selective serotonin reuptake inhibitor, fluvoxamine with a putative σ-1 agonistic action. 7…”