A Renal Protocol for All Ages and All Indications: Mercapto-Acetyl-Triglycine (MAG3) With Simultaneous Injection of Furosemide (MAG3-F0): A 17-Year Experience

Sfakianakis, George N.; Sfakianaki, Efrosyni; Georgiou, Mike; Serafini, Aldo N.; Ezuddin, Shabbir; Kuker, Russ; Zilleruelo, Gastón; Strauss, José; Abitbol, Carolyn; Chandar, Jayanthi; Seeherunvong, Wacharee; Bourgoignie, Jacque; Roth, David; Leveillee, Raymond J.; Bird, Vincent G.; Block, Norman L.; Gosálbez, Rafael; Labbie, Andrew; Guerra, Jorge J. Llibre; Yrizarry, Jose M.

doi:10.1053/j.semnuclmed.2008.11.001

Cited by 32 publications

(14 citation statements)

References 20 publications

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“…Additionally, diagnosis of transient hypothyroidism is important to avoid lifelong unnecessary therapy. [31][32][33][34] In the current study, the children with thyroid agenesis had higher occurrence of language deficit and lower IQ in comparison to other CH children with different etiologies, in agreement with previous studies. [35][36][37][38] A previous study conducted with 100 children with CH and 100 children without the disease, reported that children with thyroid agenesis had a higher frequency of phonological deviation compared with those with other CH etiologies.…”

Section: Discussionsupporting

confidence: 91%

Thyroid scintigraphy indications based on clinical experience

Elsayeed¹,

Ali²,

Ahmed³

et al. 2019

Egyptian Journal of Neck Surgery and Otorhinolaryngology

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Objective: Thyroid scintigraphy (TS) offers valuable information on thyroid anatomy and functional state of the gland. It is currently employed in both diagnosis and management of thyroid disorders. Data of 440 patients with thyroid disorders referred to thyroid scintigraphy at Sohag University Hospital has been analyzed in this study. Diagnostic contribution and indication of TS to thyroid disorders in adult and children have been assessed. Methods: It is a hospital-based cross-sectional descriptive study where all cases referred for TS at Sohag Institute Nuclear Medicine Unit from the 1 st of November 2015 to the 31 th of October 2018 were considered. Results: Four hundred forty patients were referred to our unit with 84% female. The mean patient's age was 43.0 years. Sixty percent of the patients were referred for thyroid scan due to primary toxic goiter (Grave's disease), the second indication was post-thyroidectomy especially in differentiated thyroid cancer to estimate residual cancer thyroid and starting radioactive iodine treatment. Conclusion: Thyroid scintigraphy is an integral part of thyroid evaluation. However, it has been shown to be of small practical use in euthyroid patients with diffuse or multinodular goiters, or adult patients with hypothyroidism. It has great diagnostic and prognostic roles in congenital hypothyroidism. This emphasizes the importance of increasing the clinicians' awareness of TS when indicated and when not necessarily needed.

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Section: Discussionsupporting

confidence: 91%

Thyroid scintigraphy indications based on clinical experience

Elsayeed¹,

Ali²,

Ahmed³

et al. 2019

Egyptian Journal of Neck Surgery and Otorhinolaryngology

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“…42–44 In addition, individuals with VACTERL association frequently have GU anomalies. 45 Physical examination may yield findings warranting further medical/surgical interventions.…”

Section: Suggested Diagnostic Approachmentioning

confidence: 99%

An Approach to the Identification of Anomalies and Etiologies in Neonates with Identified or Suspected VACTERL (Vertebral Defects, Anal Atresia, Tracheo-Esophageal Fistula with Esophageal Atresia, Cardiac Anomalies, Renal Anomalies, and Limb Anomalies) Association

Solomon¹,

Baker²,

Bear³

et al. 2014

The Journal of Pediatrics

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“…For dynamic imaging 99m Tc-mercaptoacetyltriglycine (MAG-3) and diethylenetriaminepentaacetic acid (DTPA) are the most commonly used tracers, whereas MAG-3 is going to replace DTPA because of superior extraction efficiency. It was proposed that MAG-3 scintigraphy can be useful for discrimination of AR from ATN [59]. Despite a reasonable perfusion and tracer extraction in ATN as assessed in these studies, tracer excretion rate is low, whereas one of the typical findings in AR is impaired perfusion.…”

Section: Imaging Allograft Functionmentioning

confidence: 95%

Non-Invasive Diagnosis of Acute Renal Allograft Rejection − Special Focus on Gamma Scintigraphy and Positron Emission Tomography

Grabner¹,

Kentrup²,

Schnöckel³

et al. 2013

Current Issues and Future Direction in Kidney Transplantation

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The number of patients treated for end-stage renal failure continuously increases. "ecause treatment alternatives are limited and transplants are often the first therapeutic choice, the numbers of patients joining the waiting lists in countries world-wide rises. "t present transplantation medicine is one of the most progressive fields of medicine. Gradually the half-life of renal transplants improved and the five years survival rate ranges now above % [ ]. Despite of the advances made within the last decades, acute rejection "R is still a risk for graft survival. The incidence of rejection episodes depends on several factors, e.g., the organ status , co-morbidities, medication and compliance. Thus, in different situations the incidence of "R varies between -% in the first year after transplantation [ ], and, in most cases, cellular and humoral immunity mediated rejections can be distinguished. Usually, "R proceeds substantially as an acute cellular rejection whereas humoral rejection comprises only a smaller proportion of "R [ ]. Every single episode of an "R is a negative prognostic factor, increasing the risk for development of chronic allograft deterioration and worsening long-term graft survival [ ]. Interestingly, the impact of "R on chronic renal allograft failure as the main cause for death-censored graft-loss after kidney transplantation increases, whereas the severity of the episode itself is an independent risk factor [ -]. Therefore, early detection and rapid and effective treatment of "R are essential to preserve graft`s function. Clinically established screening methods such as elevated serum creatinine, occurrence or aggravation of proteinuria, oliguria, hypertension, graft tenderness, or peripheral edema, often lack the desired sensitivity and specificity for early diagnoses of "R. Hence,a compelling need for high sensitive

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A Renal Protocol for All Ages and All Indications: Mercapto-Acetyl-Triglycine (MAG3) With Simultaneous Injection of Furosemide (MAG3-F0): A 17-Year Experience

Cited by 32 publications

References 20 publications

Thyroid scintigraphy indications based on clinical experience

Thyroid scintigraphy indications based on clinical experience

An Approach to the Identification of Anomalies and Etiologies in Neonates with Identified or Suspected VACTERL (Vertebral Defects, Anal Atresia, Tracheo-Esophageal Fistula with Esophageal Atresia, Cardiac Anomalies, Renal Anomalies, and Limb Anomalies) Association

Non-Invasive Diagnosis of Acute Renal Allograft Rejection − Special Focus on Gamma Scintigraphy and Positron Emission Tomography

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