A Reliable HPLC-UV Method for the Simultaneous Determination of Three Antiretroviral Drugs in Human Blood Plasma Applied to Therapeutic Drug Monitoring
David Jaspe Lentino,
Eder Lara Mercado,
Indira Pájaro Bolívar
et al.
Abstract:Acquired immunodeficiency syndrome is an infectious disease caused by human immunodeficiency virus (HIV). Pharmacological antiretroviral therapy, along with therapeutic monitoring of drug plasma concentrations, facilitates adequate and effective follow-up in each patient. Our main objective was to develop and validate a high-performance liquid chromatography with ultraviolet detector (HPLC-UV) bioanalytical method for the simultaneous quantification of plasma concentrations of three commonly used antiretrovira… Show more
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