A recombinant vaccine of Riemerella anatipestifer OmpA fused with duck IgY Fc and Schisandra chinensis polysaccharide adjuvant enhance protective immune response

Yang, Shifa; Dong, Wenwen; Li, Guiming; Zhao, Zengcheng; Song, Ming; Huang, Zhongli; Fu, Jing; Jia, Fengjuan; Su, Lin

doi:10.1016/j.micpath.2019.103707

Cited by 15 publications

(6 citation statements)

References 32 publications

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“…TNF-α and IL-6 cytokines play eliminate inflammation, and TNF-α can influence other cells to produce additional inflammatory cytokines that will participate in the body's immune response ( 27 , 28 ). IL-2 and IL-4 are essential regulators of cellular immune function and are secreted by the Th1 and Th2 cell subgroups, respectively ( 29 , 30 ). Increasing evidences indicated that plant-active polysaccharides could regulate the levels of cytokines, such as TNF-α, IL-2, IL-4 and IL-6.…”

Section: Discussionmentioning

confidence: 99%

Effects of Chinese yam polysaccharides on the immune function and serum biochemical indexes of broilers

Deng

Zhang²,

Chang³

et al. 2022

Front. Vet. Sci.

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The purpose of this experiment was to investigate the effects of Chinese yam polysaccharides (CYP) in diets on the immune function of broilers. A total of 360 (1-day-old, sex balance) healthy growing broilers with similar body weight (39.54 ± 0.51 g) were randomly divided into control (0.00 g/kg), CYP I (0.25 g/kg), CYP II (0.50 g/kg), and CYP III (1.00 g/kg) groups. Each group contains 3 replicates with 30 broilers in each replicate, and the feeding trial lasted 48 d. The results showed that compared with the control group, the CYP II group had higher thymus index, serum IgA, complement C3, C4, IGF-I, T3, T4, INS, GH, IL-2, IL-4, IL-6, and TNF-α levels (P < 0.05) at 28, 48 d, respectively. In addition, the spleen index, serum IgM and IgG concentrations in CYP II group were higher than those in the control group at 28 d (P < 0.05). Results indicated that 0.50 g/kg CYP supplementation improved the immune function of broilers, and the CYP has a potential biological function as a green additive in broilers.

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Section: Discussionmentioning

confidence: 99%

Effects of Chinese yam polysaccharides on the immune function and serum biochemical indexes of broilers

Deng

Zhang²,

Chang³

et al. 2022

Front. Vet. Sci.

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“…Gomisin G showed the most anti-HIV pharmacological activity with an EC 50 value of 0.006 μg/ml among all other natural dibenzocyclooctadiene lignans which have been isolated from Schisandra chinensis. 76 Yang et al 77 stated that Schisandra chinensis polysaccharide (SCP) revealed considerable potential in clinical applications because of excellent immunostimulatory effects on the ompA-Fc vaccine and promoting macrophages activity. Chung et al 78 suggested that Schisandra chinensis berry ethanol extract (SCE) has potential to consider as a novel therapeutic agent for the prevention of steatosis.…”

Section: Modern Pharmaceutical Sciencementioning

confidence: 99%

Schisandra chinensis, Five Flavor Berry, a Traditional Chinese Medicine and a Super-Fruit from North Eastern China

Sun¹,

Shahrajabian²,

Cheng³

2021

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Introduction:The aim of this review was to summarize the most important traditional and modern health benefits of Schisanda berry. Methods: We used PubMed, Science Direct and Google to search for and collect scientific publication for a full evaluation of current evidence in the literature indicating the potential role of Schisanda berry. Results: The traditional Chinese medicine (TCMs) is essential components of alternative medicines. Schisandra berry (Schisandra chinensis (Turcz.) Baill. (Magnoliaceae) or Wu-Wei-Zi, which means the fruit of five tastes is a commonly used herb in traditional Chinese medicine (TCM). The five tastes of Schisandra berry refer to its influence on the five visceral organs in the body. It is one of the oldest medicinal plants used in East of Asia, especially traditional Chinese medicine. S. chinensis is mainly distributed in provinces in northern China including Heilongjiang, Jilin and Liaoning. S. chinensis can treat lung-Qi and kidney-Yin deficiencies, relieve coughs and asthma and stop persistent diarrhea. S. chinensis has been used to treat sleep disorder in traditional Chinese medicine and a tonic for kidney and brain in traditional Chinese medicine. Its extracts may apply as a preservative and as an additive to increase the flavor, taste and nutritional value of food. The five important components of S. chinensis are Schisandrol B, Schisandrin A, γ-Schisandrin, Gomisin N and Schisandrin C. Conclusion:The most important pharmacological effects of Schisandrol B are antiallergy, liver protection and anticarcinogenic effects; Schisandrin A has role in liver protection and anti-carcinogenic effect; γ-Schisandrin has liver protection and anti-carcinogenic effect, Gomisin N has anti-proliferative, pro-apoptis HepG2 cells, anti-hepatitis, anti-HIV, anti-carcinogenic effect; and Schisandrin C has protect liver, anti-HIV, anti-catchinogenic effect and anti-hepatitis. The treatment with natural herbal medicine which are also super-fruit and non-synthetic drug is recommended.

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“…The main function of SC is to nourish the lungs and kidneys and remove dampness. [44][45][46] The medicinal value of SC is mainly reflected in antifatigue properties, prevention of mild cognitive impairment, 47,48 enhanced immunity, 49 anticancer effects, 45 amelioration and prevention of Parkinson's disease (PD), 50 amelioration of age-related muscle wasting, 51 and anti-atherosclerotic properties. 52 Schisandrin is the main effective component of SC, which was previously considered to be able to treat AD; 53 it has antitumor effects, 54 provides protection against central ischemia recurrence, 55 and treats neurodegenerative disease.…”

Section: Schisandra Chinensis (Turcz) Baillmentioning

confidence: 99%

<p>Traditional Chinese Medicine Jiuwei Zhenxin Granules in Treating Depression: An Overview</p>

Wang

2020

NDT

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Depression is known as "Yu Zheng" in traditional Chinese medicine (TCM). Jiuwei Zhenxin granules (JZG) is a type of TCM. According to TCM theory, it nourishes the heart and spleen, tonifies Qi, and tranquilizes the spirit, and may also has effects in the treatment of depression. Here, we systematically reviewed recent basic and clinical experimental studies of JZG and depression, including studies of the pharmacological mechanisms, active ingredients, and clinical applications of JZG in depression treatment. This review will deepen our understanding of the pharmacological mechanisms, drug interactions, and clinical applications of TCM prescriptions and provide a basis for the development of new drugs in the treatment of depression.

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A recombinant vaccine of Riemerella anatipestifer OmpA fused with duck IgY Fc and Schisandra chinensis polysaccharide adjuvant enhance protective immune response

Cited by 15 publications

References 32 publications

Effects of Chinese yam polysaccharides on the immune function and serum biochemical indexes of broilers

Effects of Chinese yam polysaccharides on the immune function and serum biochemical indexes of broilers

Schisandra chinensis, Five Flavor Berry, a Traditional Chinese Medicine and a Super-Fruit from North Eastern China

<p>Traditional Chinese Medicine Jiuwei Zhenxin Granules in Treating Depression: An Overview</p>

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