A recidivant primary cardiac osteosarcoma: the role of bone scans

Gomez-Rubin, Maria Carmen; Rios, Juan Carlos S.; Dobarro, David; Sánchez‐Recalde, Ángel; Bret-Zurita, Montserrat; Filgueiras, David; Moreno-Yanguela, Mar; Maté, I; Nistal, Manuel; López-Sendón, José

doi:10.1016/j.carpath.2008.07.005

Cited by 8 publications

(8 citation statements)

References 16 publications

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“…Clinical manifestations of cardiac tumors depend on their anatomical location and reflect the degree of obstruction, invasion, and embolization of specific intracardiac structures [4,16]. Most patients present with dyspnea secondary to mitral valve obstruction, although arrhythmias and pericardial tamponade are seen as well [3,4,28]. Our patient presented with heart failure, arrhythmia (atrial flutter) and valvulopathy (mitral stenosis).…”

Section: Discussionmentioning

confidence: 87%

A primary cardiac osteosarcoma: Case report and review of the literature

Aguilar

Donet

Galarreta

et al. 2013

Journal of Cardiology Cases

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Primary cardiac osteosarcoma is a rare and aggressive neoplasm that can be difficult to diagnose. We report a case of a previously healthy 49-year-old woman who presented with dyspnea, atrial flutter, and heart failure. A mass was visualized in her left atrium by echocardiography and cardiac computed tomography, and the diagnosis of cardiac myxoma was raised. The patient subsequently underwent surgical resection of the mass and atrial reconstruction. Surprisingly, histological and immunohistological analyses revealed the mass to be an osteosarcoma. The patient received chemotherapy and radiotherapy. Eight months later, she has shown evidence of local recurrence. We briefly discuss primary osteosarcomas in the cardiac cavity and their management.

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Section: Discussionmentioning

confidence: 87%

A primary cardiac osteosarcoma: Case report and review of the literature

Aguilar

Donet

Galarreta

et al. 2013

Journal of Cardiology Cases

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“…There have been only a few cases of primary cardiac osteosarcomas recorded [54]. Additionally, it is the most common bone malignant tumor.…”

Section: Primary Cardiac Sarcomamentioning

confidence: 99%

State of the art paper Sarcomas of the heart as a difficult interdisciplinary problem

Ostrowski¹,

Marcinkiewicz²,

Kośmider³

et al. 2014

aoms

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Cardiac tumors are assumed to be a rare entity. Metastases to the heart are more frequent than primary lesions. Sarcomas make up the majority of cardiac malignant neoplasms. Among them angiosarcoma is the most common and associated with the worst prognosis. Malignant fibrous histiocytoma comprises the minority of cardiac sarcomas and has uncertain etiology as well as pathogenesis. Transthoracic echocardiography remains the widely available screening examination for the initial diagnosis of a cardiac tumor. The clinical presentation is non-specific and the diagnosis is established usually at an advanced stage of the disease. Sarcomas spread preferentially through blood due to their immature vessels without endothelial lining. Surgery remains the method of choice for treatment. Radicalness of the excision is still the most valuable prognostic factor. Adjuvant therapy is unlikely to be effective. The management of cardiac sarcomas must be individualized due to their rarity and significant differences in the course of disease.

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“…Since then, a few cases have been reported with MR images, however, with no detailed description of MRI findings and no contrast-enhancement study included. According to previous reports, cardiac osteosarcomas appear to be irregularly lobulated and may have variable heterogeneous SI on T1WI and heterogeneously high SI on T2WI (2, 4, 6, 7, 9). In our case, the tumor showed mildly heterogeneous and high SI on both T1WI and T2WI.…”

Section: Discussionmentioning

confidence: 88%

“…Depending on the predominant component, osteosarcomas can be subgrouped as osteoblastic, chondroblastic, or fibroblastic (3). Macroscopically, the tumor may be well circumscribed and pseudoencapsulated, or infiltrate into the surrounding tissues and calcification, necrosis, or hemorrhage within the tumor can be seen (5, 6). The characteristic CT findings of cardiac osteosarcomas have been reported as a low attenuation mass with dense mineralization (3, 7).…”

Section: Discussionmentioning

confidence: 99%

MR Imaging Findings of a Primary Cardiac Osteosarcoma and Its Bone Metastasis with Histopathologic Correlation

et al. 2011

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An osteosarcoma of cardiac origin is extremely rare, and a comprehensive description of MR imaging (MRI) findings of cardiac osteosarcoma and its metastasis in the femur have not been reported in the literature. We present a case of cardiac osteosarcoma in a 47-year-old woman and its metastasis to the femur, focusing on the description of MRI findings of the cardiac and metastatic bony osteosarcoma with a histopathologic correlation.

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A recidivant primary cardiac osteosarcoma: the role of bone scans

Cited by 8 publications

References 16 publications

A primary cardiac osteosarcoma: Case report and review of the literature

A primary cardiac osteosarcoma: Case report and review of the literature

State of the art paper Sarcomas of the heart as a difficult interdisciplinary problem

MR Imaging Findings of a Primary Cardiac Osteosarcoma and Its Bone Metastasis with Histopathologic Correlation

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